TLDR Minoxidil may promote hair growth by mimicking a natural body process.
The document discussed the potential role of endothelium-derived relaxing factor (EDRF), identified as the nitroxide free radical (NO), in vascular physiology and its possible connection to hair growth. It suggested that minoxidil, a known vasodilator, might act as an EDRF agonist, sharing similar mechanisms by activating guanylate cyclase. This activation was thought to account for their vasodilatory properties. The document proposed that EDRF might have a separate action on hair growth, which could explain the effects of minoxidil in promoting hair growth.
January 2022 in “Wiadomości lekarskie (Warsaw Poland)” MSM reduces hair loss and promotes hair growth in male mice.
February 2020 in “The Pharmaceutical Society of Japan” 
April 2018 in “Journal of Investigative Dermatology” Minoxidil didn't significantly increase hair growth in minipigs.
14 citations
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January 2015 in “Skin appendage disorders” Minoxidil treatment for hair loss can cause scalp allergy and severe hair loss.
5 citations
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January 2015 in “Journal of clinical & experimental dermatology research” MorrF improves hair growth better than minoxidil alone.
The herbal extract CS-10-H significantly promotes hair growth in mice.
56 citations
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April 2007 in “Journal der Deutschen Dermatologischen Gesellschaft” Minoxidil works better for female hair loss than alfatradiol, both safe.
January 2007 in “Strait Pharmaceutical Journal” Water-soluble minoxidil effectively promoted hair growth in mice.
1 citations
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September 2002 in “PubMed” Minoxidil helps stimulate hair growth and reduce hair loss in women with androgenic alopecia.
