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      research Physiological changes in the skin during pregnancy

      96 citations , January 1997 in “Clinics in Dermatology”
      This study found that G protein-coupled estrogen receptor enhances melanin synthesis in melanoma cells through cAMP-PKA-MITF-TYR signaling, suggesting its potential as a drug target for chloasma treatment.

      research PHYSIOLOGIC SKIN CHANGES ASSOCIATED WITH PREGNANCY

      64 citations , June 1992 in “International Journal of Dermatology”
      Pregnancy often causes skin changes like darkening, stretch marks, and hair growth, which may improve after childbirth.

      research Physiological dermatological changes during pregnancy: literature review

      March 2026 in “International Journal of Health Science”
      In this narrative literature review, researchers found that physiological skin changes are extremely common during pregnancy due to hormonal and circulatory adaptations, emphasizing the need for healthcare professionals to recognize these changes to provide proper guidance to pregnant women and avoid unnecessary interventions.

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