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research Captopril and alopecia: A case report and review of known cutaneous reactions in captopril use
Captopril may cause hair loss, as shown by a woman's hair regrowing after stopping the medication.
research Enzalutamide/finasteride/goserelin/zoledronic-acid
research Relation of 24-Hour Urinary Aldosterone Levels with Nondipper Blood Pressure Pattern in Normotensive Individuals
This study found that individuals with a nondipper blood pressure pattern had significantly higher 24-hour urinary aldosterone levels than those with a dipper pattern.
research Repurposing of approved cardiovascular drugs
This review discusses the drug repurposing of cardiovascular medications like aspirin and statins for new uses, including potential anti-tumor effects, noting promising experimental outcomes but less conclusive clinical trials, particularly in the field of cancer treatment.
research Adrenaline Infiltration in The Recipient Area During Follicular Unit Extraction Using the Implanter Technique: A Prospective Observational Study
This study found that infiltrating dilute adrenaline into the recipient area during implanter-based FUE hair transplantation significantly reduced intraoperative bleeding, improving graft precision and visualization, without major safety concerns among the 50 patients observed.
research Nurses' Drug Alert
Some drugs can cause serious side effects, like hypoglycemia from mix-ups, skin reactions, or depression, and while penicillamine may help rheumatoid arthritis more than auranofin, it has more severe side effects.
research A INFLUÊNCIA DA BAIXA ESCOLARIDADE E DA BAIXA RENDA NA NÃO ADESÃO AO TRATAMENTO DA HIPERTENSÃO ARTERIAL SISTÊMICA: REVISÃO DE LITERATURA
This collection reviews interdisciplinary research from Brazilian institutions on social development issues, with no new study results reported; it highlights the importance of these discussions for improving quality of life.
research Fast-tracked innovation: orforglipron approval under the FDA’s National Priority Voucher program
This study highlights the approval of orforglipron under the FDA's National Priority Voucher program, emphasizing its significance as a convenient oral treatment option with beneficial effects on glycemic and lipid profiles for diabetes and obesity management.
research A comparative, open-label, randomised study; evaluating efficacy of a hand-held device using a combination of vibration and cold, versus only vibration; in reducing the pain sensation of multiple local anaesthesia injections during hair transplant
This study found that the Leni wand device, which combines cold and vibration, was more effective at reducing pain from local anesthesia injections during hair transplant surgery than a device using only vibration, although results were obtained solely from a male participant group.
research Recurrent Priapism after Initiation of Oral Minoxidil
In this case report, a patient with end stage renal disease and sickle cell trait experienced recurrent priapism episodes after starting oral minoxidil for hypertension, which resolved after discontinuing the medication, suggesting minoxidil as a potential trigger in susceptible individuals.
research Recipient Site Anesthesia and Hemostasis
This abstract discusses the challenges and considerations of hair restoration surgery related to the skin's rich neuro-vascular supply and does not report new clinical results.
research Effective strategies to reduce pain during platelet-rich plasma scalp injections: A randomized split-scalp study
This study observed that using ice pack compression or a vibration anesthesia device reduced pain during inactivated PRP scalp injections in patients with alopecia, suggesting both as inexpensive and accessible pain-relief options.
research Modulation of the 6-position of benzopyran derivatives and inhibitory effects on the insulin releasing process
This study identified certain benzopyran derivatives with a bulky tert-butyloxycarbonylamino group as effective KATP channel openers that inhibit insulin secretion in rat pancreatic islets.
research Emerging medications
research Alleviation of Mechanical Allodynia by 14,15-Epoxyeicosatrienoic Acid in a Central Poststroke Pain Model: Possible Role of Allopregnanolone and δ-Subunit-Containing Gamma-Aminobutyric Acid A Receptors
This study found that in a rat model, 14,15-EET may alleviate central poststroke pain by enhancing thalamic inhibition through neurosteroid signaling, potentially outperforming gabapentin in early-stage treatment.
research Role of local application of autologous platelet-rich plasma in the management of pressure ulcers in spinal cord injury patients
research Relationship between Serum Concentrations, Hemodynamic Effects, and Cardiovascular Lesions in Dogs Treated with Minoxidil
Higher minoxidil doses in dogs cause faster heart rate, lower blood pressure, and heart issues.
research title.alternative
This study found that supraphysiological doses of testosterone alter endothelial relaxation pathways in hypertensive rats, with varied contributions from nitric oxide, prostanoids, and endothelium-derived hyperpolarizing factors, influenced by estrogen and dihydrotestosterone levels.
research Emergency Wound Infection Monitoring and Treatment Based on Wearable Electrochemical Detection and Drug Release with Conductive Hydrogel
This study developed a closed-loop system for emergency wound care that monitors infection in real-time using biomarkers and delivers amikacin-loaded liposomes for treatment, integrating a conductive hydrogel for environmental protection and antibacterial benefits.
research Mineralocorticoid Receptor Antagonists—A New Sprinkle of Salt and Youth
This study found that using mineralocorticoid receptor antagonists with glucocorticoid therapy improved wound healing in diabetic animals by enhancing keratinocyte proliferation and epithelialization.
research Multistage Transdermal Nitric Oxide Delivery System for the Efficient Treatment of Androgenic Alopecia
This study developed a nitric oxide delivery system using PVA films and HA liposomes, which enhanced hair follicle vitality and repaired blood vessels in androgenic alopecia by promoting angiogenesis and reducing inflammation through the HIF-1 signaling pathway.
research Extracellular ATP and Adenosine Signaling in Arabidopsis: Investigating Cellular Modulation
In this study, researchers using Arabidopsis thaliana found that adenosine may inhibit root hair growth and stomatal opening, suggesting it plays a signaling role in plants similar to its function in animal cells, potentially revealing a new adenosine-like receptor pathway.
research Voltammetric sensing of minoxidil using a molecularly imprinted polymer (MIP)-modified carbon paste electrode
This study developed and optimized a molecularly imprinted polymer-based electrochemical sensor, demonstrating its ability to detect minoxidil with high sensitivity and selectivity at concentrations as low as 0.3 nM, and successfully applied it for minoxidil measurement in various real sample matrices.
research MP45-10 HISTOMORPHOMETRICAL EVALUATION OF THE CORPUS CAVERNOSUM OF HYPERTENSIVE RATS TREATED WITH 5-?-REDUCTASE INHIBITORS
This study found that Sonic Hedgehog protein treatment enhanced the sprouting and regeneration of pelvic ganglia and cavernous nerves after injury, with localization of delivery affecting outcomes.
research Nitric Oxide: Physiological Functions, Delivery, and Biomedical Applications
This review discusses nitric oxide's physiological roles and the development of strategies for delivering it exogenously, without presenting new clinical results.
research AORTOCAVAL PARAGANGLIOMA IN VON HIPPEL-LINDAU DISEASE
This case report discusses a patient with VHL-associated paraganglioma, highlighting the importance of genetic testing and monitoring in those with VHL disease, due to high mutation penetrance and associated risks.
research Adenosine A2B receptor: A pathogenic factor and a therapeutic target for sensorineural hearing loss
Blocking adenosine A2B receptor may prevent or treat hearing loss.
research Use of Verteporfin with Dermal Wounding to Regenerate New Hair in Androgenetic Alopecia
In this study, two male patients with androgenetic alopecia who had previously undergone hair transplants showed increased hair regrowth after receiving verteporfin injections, with a 63% mean increase in dense donor sites, 38% in thinning areas, but no growth in bald areas.
research The Sodium Valproate: Doctor Jekyll and Mister Hyde
This study reported that sodium valproate completely stopped epilepsy in 43% of patients and reduced seizures by 50% in 22% of patients who were resistant to other anticonvulsants.