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JAK inhibitors are effective in treating various immune-related diseases, not just rheumatoid arthritis.

Tofacitinib is safe and effective for severe alopecia areata, but hair loss may return 2 months after stopping treatment.

Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.

Postpartum depression is linked to changes in brain chemicals, inflammation, stress, and certain genes, and can potentially be identified by markers like specific steroids, serotonin levels, and vitamin D levels.

Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

The article concludes that the wool follicle is a valuable model for studying tissue interactions and has potential for genetic improvements in wool production.

New single-cell analysis techniques are improving our understanding of stem cells and could help in treating diseases.

Hair loss in men treated best with early medication or transplant, new treatments researched.

Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.

TCDD speeds up skin barrier formation by increasing certain gene expressions.

Feather growth and regeneration involve complex patterns, stem cells, and evolutionary insights.

The document concludes that rapid identification, isolation, and strict infection control are crucial to manage SARS outbreaks.

White lupin uses specific genes to grow root hairs and access phosphorus when it's scarce.

The three estrogen receptor genes are highly expressed in zebrafish neuromasts during development.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

The study identified and characterized new keratin genes linked to hair follicles and epithelial tissues.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

Nanoparticles can enter the skin, potentially causing toxicity, especially in damaged skin.

Drugs targeting the JAK/STAT pathway can improve atopic dermatitis but vary in effectiveness for vitiligo and alopecia areata, with generally mild safety concerns.

Finasteride for hair loss may cause persistent sexual symptoms, depression, anxiety, and lower quality of life.

Genes and hormones cause hair loss, with four genes contributing equally.

New genes found linked to balding, may help develop future treatments.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

Male hormones, or androgens, affect women's health in areas like mood and bone density, and hormone replacement therapy using antiandrogenic progestogens can improve mood disorders and alertness in menopausal women.

The document concludes that understanding hair follicle cell cycles is crucial for hair growth and alopecia research, and recommends specific techniques and future research directions.

Ectodermal dysplasia causes various symptoms and early treatment is important for eye, dental, and skin issues.

Cysteine-rich keratins evolved independently in mammals, reptiles, and birds for hard skin structures like hair, claws, and feathers.