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The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

About 7% to 15% of Iranian women have polycystic ovary syndrome, depending on the criteria used to diagnose it.

Diagnosing PCOS in teenagers is challenging and should use strict criteria to avoid misdiagnosis and unnecessary worry.

EGFR inhibitors often cause skin problems and other side effects, but these are usually reversible and can be managed to keep patients comfortable.

The document concludes that hair is complex, with a detailed growth cycle, structure, and clinical importance, affecting various scientific and medical fields.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

Pregnancy can cause skin pigmentation, stretch marks, and changes in hair, nails, and sweat glands, with most resolving after birth.

PCOS is a common hormonal disorder in women, marked by symptoms like hair growth and menstrual issues, and requires personalized treatment.

Some common medications can harm male fertility, but many effects can be reversed.

Cancer can hijack the body's cell repair system to promote tumor growth, and targeting this process may improve cancer treatments.

Hidradenitis suppurativa treatment should be tailored to the individual, with quitting smoking being important.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

DHT, a testosterone byproduct, causes male pattern baldness.

AMH helps estimate ovarian reserve but doesn't predict pregnancy chances; age is more important.

HIV can cause unusual and severe skin problems that are hard to treat.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Most pregnant women experience skin darkening and hair changes, with these effects usually going away after giving birth.

Some plants used in traditional medicine may help treat cancer because they contain proteins that can inactivate ribosomes.

Bee venom might be a good alternative treatment for various skin conditions because it has many healing properties.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

Hairless mice lack fur due to a genetic mutation affecting skin response, not hormone issues.

Steroidogenic isoenzymes may help improve treatments for common hair loss.

Small changes in hormones can significantly impact health, showing the importance of sensitive testing for chemicals that disrupt hormones.

Minoxidil use during pregnancy may cause fetal harm.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

Fungal infections in lab animals can interfere with research.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

Birth control pills combined with bicalutamide are more effective at reducing excessive hair growth in women with PCOS than birth control pills alone.

The document concludes that health care providers should offer culturally competent care and more research is needed to improve health outcomes for transgender individuals.

Women with PCOS have more emotional and body image issues than healthy women.