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This study identified AH01 derivatives and related compounds with high antischistosomal efficacy and reduced antiandrogenic effects, suggesting potential new directions for schistosomiasis drug development.

This study identified a novel mutation in the coproporphyrinogen oxidase gene, contributing to hereditary coproporphyria in a family, with decreased enzyme activity observed in the affected members.

This article reviews the genetic mutations causing male pseudohermaphroditism from 17 beta-HSD-3 and 5 alpha-RD-2 deficiencies and reports no new clinical findings.

This case report describes a 60-year-old woman with an ovarian Leydig cell tumor leading to elevated testosterone levels and hirsutism, highlighting the need to consider androgen-secreting tumors in similar postmenopausal cases.

This study suggests that polyamines regulate CK2 enzyme activity and its subcellular distribution, as demonstrated in mouse models and cell cultures with elevated levels of ornithine decarboxylase.

In this study, Urtica dioica extract was found to significantly downregulate 5-alpha-reductase type II gene expression in skin cells, suggesting potential usefulness against androgenic skin diseases.

This study suggests that glaucoma patients may face increased risk of optic nerve injury if prescribed medications that can lower blood pressure.

This article reports that the rise in erectile dysfunction among young men may be linked to mental health issues and societal pressures, with online communities often encouraging risky substance use like anabolic steroids and finasteride, which can exacerbate psychological and physical health problems.

This case report describes two German shepherd dogs with prostatitis that showed favorable responses to treatment with finasteride, phenazopyridine, and enrofloxacin.

This study found that breast cancer treatment with chemotherapy, radiotherapy, and/or hormonal therapy led to a significant increase in blood urea and creatinine levels, indicating nephrotoxicity among non-diabetic, non-cardiac post-menopausal patients with infiltrating ductal carcinoma.

Patients follow treatment well, but many change medicines; good information helps compliance.

This article discusses various potential causes of hair loss in women undergoing renal replacement therapy and emphasizes the importance of thorough patient evaluation, but it reports no new research findings.

In this study, researchers used cryo-electron microscopy to reveal how the natural compound osthole inhibits TRPV3 channels by binding to specific sites, changing the channel's conformation.

This study found that measuring specific steroid hormone levels can aid in diagnosing P450 oxidoreductase deficiency, a subtype of congenital adrenal hyperplasia, by distinguishing affected patients from healthy individuals.

Researchers observed that dutasteride and finasteride caused structural changes in the penises of both control and hypertensive rats, with dutasteride having a more pronounced effect on the corpus cavernosum.

This study classified dutasteride, fesoterodine, and finasteride as beneficial for older or frail elderly patients, while suggesting caution or avoidance of α-blockers and antimuscarinics in this group.

This review concludes that preoperative hormonal stimulation with testosterone or DHT may help increase penile length and glans circumference, easing hypospadias surgery and potentially reducing postoperative complications.

This study found that in semi-coarse wool sheep of the Ukrainian Carpathian Mountain breed, changes in microflora and grease composition are linked to increased felting in wool, due to wetter, more alkaline fleece conditions that promote bacterial and mold growth and alter fatty acid balances.

This report describes a complex case of postmenopausal hyperandrogenism with virilization and concurrent rare ovarian tumors, highlighting the critical role of interdisciplinary collaboration in diagnosing and managing such challenging scenarios.

This case report describes a 72-year-old woman with a steroid cell tumor of the ovary, highlighting the critical role of imaging, biochemical evaluation, and pathology in diagnosing and managing hormonally active ovarian tumors that cause virilization in postmenopausal women.

In this study, researchers analyzed spermogram data from men with diagnosed infertility in Ukraine, aiming to identify the most common sperm disorders, and they found that the study primarily involved men with primary infertility, compared to a control group of healthy men with confirmed fertility.

This study found that finasteride-induced DHT deficiency altered estrogen receptor expression in the epididymis, potentially destabilizing its function.

In this case report, the researchers described a postmenopausal woman with androgenic symptoms who was found to have a benign Leydig cell tumor of the left ovary, indicated by elevated testosterone levels and MRI findings, which was successfully treated with surgery.

This article reviews current diagnostic criteria and treatment strategies for polycystic ovary syndrome, highlighting the role and limitations of the Rotterdam criteria and anti-Müllerian hormone, but it reports no new findings.