20 citations
,
March 2020 in “International Journal of Biological Macromolecules” Lower acetylation makes chitin nanofibers thinner and more suitable for various uses.
20 citations
,
October 2016 in “Veterinary dermatology” This study reports that generalized discoid lupus erythematosus is a recognized canine variant of cutaneous lupus erythematosus, resembling its human counterpart, with varied treatment responses and common relapses.
20 citations
,
January 2014 in “Journal of skin cancer” This study found that most completely excised basal cell carcinomas in the head and neck were nodular, with a 2.7% recurrence rate, particularly in median areas, likely due to anatomical and histopathological factors.
20 citations
,
March 2013 in “Journal of Lipid Research” This study examined the structural and biochemical mechanisms of human lipocalin prostaglandin D synthase, detailing substrate and product binding processes at the catalytic site and suggesting potential for drug delivery targeting hydrophobic molecules.
19 citations
,
August 2018 in “International Journal of Dermatology” In this study, lupus panniculitis of the scalp was associated with a high incidence of recurrence and progression to systemic lupus erythematosus, despite various treatments showing complete response within weeks.
19 citations
,
August 2011 in “Facial Plastic Surgery Clinics of North America” This article discusses the use of hair transplantation as a reconstructive method to restore hair in various areas affected by defects, highlighting its advantages in providing natural-looking restoration.
18 citations
,
January 2017 in “Dermatologic Surgery” This review examines intrinsic and extrinsic aging impacts and presents evidence-based lifestyle recommendations to complement cosmetic procedures for enhanced antiaging outcomes, but it reports no new clinical results.
18 citations
,
July 2016 in “Journal of The American Academy of Dermatology” This study reported that both primary and secondary cutaneous follicle center lymphomas can present with atypical scalp or forehead lesions, leading to potential misdiagnosis as other skin conditions.
17 citations
,
September 2019 in “Journal of Cell Biology” This study found that despite carrying an activating Hras mutation, hair follicle stem cells integrate into normal skin without causing tumors, unlike similar mutations in the epidermis, suggesting unique tumor-suppressing mechanisms in hair follicles.
17 citations
,
July 2017 in “International Journal of Behavioral Medicine” This study validated the Egyptian Arabic version of the Skindex-16 and found that skin conditions significantly impacted patients' quality of life, particularly in the emotional domain.
17 citations
,
May 2016 in “Archives of Dermatological Research” This study identified specific reflectance confocal microscopy features that help differentiate scarring from non-scarring alopecia, providing a non-invasive diagnostic tool.
17 citations
,
August 2014 in “American Journal of Physiology-gastrointestinal and Liver Physiology” This study found that finasteride significantly improved motor, EEG, and cellular changes in a rat model of thioacetamide-induced hepatic encephalopathy and prevented the development of hepatic coma.
17 citations
,
September 2012 in “Dermatologic Clinics” This review discusses histologic findings in alopecia and emphasizes the importance of understanding normal follicular anatomy and cycles in transverse sections, without reporting new results.
17 citations
,
October 2002 in “Dermatologic Surgery” This article provides a guide for surgeons on repairing poorly executed hair transplants, emphasizing meticulous techniques and optimal use of limited hair supply to achieve cosmetic improvements.
16 citations
,
September 2018 in “Clinical Biochemistry” This paper discusses the link between polycystic ovarian syndrome (PCOS) and health issues like infertility and cardiovascular diseases, caused by both genetic and environmental factors, but reports no new clinical findings.
16 citations
,
September 2008 in “Dermatologic Therapy” This review discusses the clinical features, genetics, and treatment of 21-hydroxylase deficiency, a common type of congenital adrenal hyperplasia, and reports no new research findings.
15 citations
,
July 2019 in “Lasers in surgery and medicine” This study found that 1,540 nm fractional erbium-glass laser treatment combined with topical minoxidil significantly increased hair regrowth in alopecia areata patches compared to minoxidil alone, with response rates of 60% versus 16%, though the long-term effects remain unknown.
15 citations
,
December 2013 This study found that in men with androgenic alopecia, moderate to severe cases were associated with the AA genotype of rs1160312, blood vanadium concentrations, and regular consumption of soy bean drinks.
14 citations
,
June 2021 in “Expert Opinion on Therapeutic Patents” This review discusses various Wnt pathway modulators developed between 2014 and 2020, highlighting their potential as treatments for diseases like cancer and osteoarthritis, but reports no new clinical results.
14 citations
,
January 2024 in “Theranostics” In this study involving a mouse model, researchers reported that intranasal delivery of protein-based CRISPR/dCas9 nanoparticles targeting the gene *Sirt1* reduced cerebral edema and increased survival following ischemic stroke, with no significant toxicity observed.
14 citations
,
October 2020 in “Scientific reports” This study found that ATM protein plays a crucial role in protecting human hair follicle melanocytes from oxidative stress, which is linked to the greying of hair.
14 citations
,
April 2017 in “Scientific Reports” This study demonstrated that using a perfusion culture bioreactor and 3D spheroid culture can enhance corneal endothelial cell expansion and support the construction of tissue-engineered corneal endothelial layers in vitro.
14 citations
,
July 2011 in “Clinics in plastic surgery” This review discusses the use of dermabrasion as an effective skin resurfacing technique for treating aging effects and reports no new clinical results.
14 citations
,
January 2006 in “Australasian journal of dermatology” This case report describes an atypical presentation of alopecia areata in a 53-year-old postmenopausal woman, which may resemble frontal fibrosing alopecia and complicate diagnosis.
13 citations
,
July 2019 in “Toxicology research” In this study, ethanamizuril was found to cause alopecia, biochemical changes, and organ damage at higher doses in rats, with a no-observed-adverse-effect level of 20 mg/kg over 30 days.
13 citations
,
January 1995 in “Postgraduate medicine” This article outlines common and serious causes of excessive body hair in women, noting that benign conditions like polycystic ovarian syndrome are treatable, while dangerous causes require swift medical attention; it reports no new results.
13 citations
,
June 2018 in “Current Urology Reports” This review suggests that while finasteride for male pattern hair loss was previously considered safe, there is now evidence associating 5-α reductase inhibitors with significant sexual and reproductive side effects.
13 citations
,
August 1980 in “Cancer” This study found that administering chemotherapy to premenopausal women with Stage II breast cancer significantly improved disease-free intervals and increased survival, while postmenopausal women receiving sufficient doses also saw prolonged disease-free periods.
12 citations
,
October 2012 in “International Braz J Urol” This study suggests that a low daily dose of finasteride may be effective in reducing recurrent priapism episodes in children and adolescents with sickle cell disease, though larger controlled studies are needed to confirm these findings.
12 citations
,
June 2006 in “Anais Brasileiros de Dermatologia” This study reports that scalp biopsies in white adults usually have 16.5 hair follicles, primarily in the anagen phase, with male samples showing fewer follicular units but more fibrous tracts in certain areas.