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High levels of ERK activity are key for tissue regeneration in spiny mice, and activating ERK can potentially redirect scar-forming healing towards regenerative healing in mammals.

Alopecia areata can be reversed by JAK inhibitors, promoting hair regrowth.

Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.

Enzymes play crucial roles in metabolism, health, and disease management.

There is no cure for alopecia areata, but treatments like JAK inhibitors show promise.

EGF controls hair growth by regulating hair follicles' growth phases.

Researchers found genes and microRNAs that control curly fleece in Chinese Tan sheep.

Testosterone is crucial for development, growth, and various body functions in mammals.

Targeted therapies for lung cancer are effective but require careful management of side effects to benefit patients.

Melanocyte stem cells in hair follicles are key for hair color and could help treat greying and pigment disorders.

Ephrins slow down skin and hair follicle cell growth.

VEGF stimulates hair cell growth and increases growth receptor levels through a specific signaling pathway.

New treatment with green tea polyphenols and nicotinamide improves skin problems from cancer therapy.

Applying InlB321/15 to wounds sped up healing in mice.

Ripretinib is effective and safe for treating advanced GIST in Chinese patients, particularly for non-gastric GISTs.

A man got six skin cancers within a year after a cell transplant for leukemia but was cancer-free 32 months later; skin checks are important post-transplant.

aPKCλ is essential for hair follicle stem cell maintenance and wound healing.

Skin symptoms can indicate endocrine disorders and have various treatments.

Ephrin-A3 helps increase and speed up hair growth in baby mice.

A Korean woman with complete hair loss regrew her hair after taking tofacitinib, with no side effects.

Tofacitinib, a JAK inhibitor, improved hair regrowth in most patients with severe alopecia areata and had minimal side effects.

Melanocytes produce melanin; their defects cause vitiligo and hair graying, with treatments available for vitiligo.

Drug approvals slowed in 2Q22, but notable drugs like Amvuttra, Camzyos, and Olumiant were approved.

VEGF helps hair grow and determines follicle size by increasing blood vessel growth.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

Targeted cancer therapies often cause serious skin problems that need careful management.

Cancer treatments targeting specific cells and the immune system can cause skin, mouth, hair, and nail problems, affecting patients' quality of life and treatment adherence.

Blocking JAK-STAT signaling can lead to hair growth.

EGFR inhibitors often cause skin problems and other side effects, but these are usually reversible and can be managed to keep patients comfortable.

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.