research Sulfatase Inhibitors: A Patent Review
The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.
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research Developmental Genetics of Color Pattern Establishment in Cats
Cat color patterns are determined early in development by gene expression and epidermal changes, with the Dickkopf 4 gene playing a crucial role.
research Expression of an Olfactomedin-Related Gene in Rat Hair Follicular Papilla Cells
FP-1 is a key protein in rat hair growth, active only during the growth phase.
research Transient Calcium Entry by Plasmalogen-Mediated Activation of Receptor Potential Cation Channel Promotes AMPK Activity
Plasmalogens activate a channel in cells that may stimulate hair growth.
research Human Hair Follicles Operate a Functional Peripheral Equivalent of the Hypothalamic-Pituitary-Somatotropic Axis Ex Vivo
Human scalp hair follicles can produce hormones and have a system similar to a brain-body communication network.
research Hairless Suppresses Vitamin D Receptor Transactivation in Human Keratinocytes
Hairless protein can block vitamin D activation in skin cells.
research Altered Dermal Fibroblasts in Systemic Sclerosis Display Podoplanin and CD90
Fibroblast changes in systemic sclerosis may help understand disease severity and treatment.
research Expression of Matrix Metalloproteinases and Tissue Inhibitor of Matrix Metalloproteinases in the Hair Cycle
MMP-2 and MMP-9 help hair grow, while their inhibitors peak when hair growth slows.
research A Pair of Transmembrane Receptors Essential for the Retention and Pigmentation of Hair
Bmpr2 and Acvr2a receptors are crucial for hair retention and color.
research Characterization of the Serotoninergic System in the C57BL/6 Mouse Skin
Mouse skin can produce and process serotonin, with variations depending on hair cycle, body location, and mouse strain.
research Sequence-Structure Based Phylogeny of GPCR Class A Rhodopsin Receptors
The research found how GPCR Class A Rhodopsin receptors are related and suggested possible substances they interact with.
research Sulphation Catalyzed by the Human Cytosolic Sulphotransferases: Chemical Defense or Molecular Terrorism?
Human enzymes can detoxify harmful substances but might also increase their cancer risk.
research Dutasteride
Dutasteride effectively treats enlarged prostate, reduces prostate cancer risk, and promotes hair regrowth with few side effects.
research Xenobiotic-Metabolizing Enzymes in the Skin of Rat, Mouse, Pig, Guinea Pig, Man, and in Human Skin Models
Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.
research Expression Profiling and Cellular Localization of Genes Associated with the Hair Cycle Induced by Wax Depilation
Researchers found new genes involved in hair growth, which could help develop new hair treatments.
research Pericardial Effusions Associated with Minoxidil
research Analysis of the Expression Pattern of the Carrier Protein Transthyretin and Its Receptor Megalin in the Human Scalp Skin and Hair Follicles: Hair Cycle-Associated Changes
The proteins transthyretin and megalin are more present in the growth phase of hair, suggesting they might affect hair health and growth.
research Psychotropic Treatment of Psychodermatologic Disorders
Psychotropic drugs can help treat skin conditions affected by mental health, but dermatologists must use them carefully due to side effects and patient concerns.
research Edible Oil-Producing Plants in the Sinja Valley, Jumla, Nepal
Traditional knowledge of edible oil-producing plants in Sinja Valley is declining due to outmigration and sociocultural changes.
research Chapter 14: Principles of Drug Metabolism
Drug metabolism affects how long a drug works, its interactions, activation, and toxicity, and is influenced by genetics, diet, illness, and other drugs.
research Quantitative Determination of Nutraceuticals in Matured Unripe Fruits of Three Edible Musa Species Using GC-MS
Unripe fruits of three banana species have many health-boosting compounds useful for medicine.
research Expert Opinion: Migraine, Psychiatric Comorbidities, and Treatment
People with migraines often have mental health conditions, and treatment should be personalized to address both issues safely.
research Hydrogel Composites for Multifunctional Biomedical Applications
Hydrogel composites have great potential in regenerative medicine, tissue engineering, and drug delivery.
research Clinical Evaluation of Cactus (Cereus Grandiflorus) Enriched Hair Oil for Hair Fall Disorders
Cactus-enriched hair oil effectively reduces hair fall and promotes hair growth with no major side effects.
research Probing the Effects of Stress Mediators on the Human Hair Follicle
Stress-related substance P may lead to hair loss and negatively affect hair growth.
research Morpho-Regulation of Ectodermal Organs
Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.
research Cystatin M/E Is a High Affinity Inhibitor of Cathepsin V and Cathepsin L by a Reactive Site Distinct from the Legumain-binding Site
Cystatin M/E strongly inhibits cathepsin V and cathepsin L, important for skin formation.
research A Role for p75 Neurotrophin Receptor in the Control of Apoptosis-Driven Hair Follicle Regression
The p75 neurotrophin receptor is important for hair follicle regression by controlling cell death.
research Olfactory Receptor OR2AT4 Regulates Human Hair Growth
A certain smell receptor in hair follicles can affect hair growth when activated by a synthetic sandalwood scent.
research Thyrotropin Releasing Hormone: A New Player in Human Hair Growth Control
TRH stimulates human hair growth and extends the hair growth phase.