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The document concludes that the risk of sexual side effects from 5-alpha-reductase inhibitors is low and often temporary, but more research is needed on potential permanent effects.

Early onset hair loss linked to genetics and androgen levels.

5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.

The research identified and described a gene important for hormone conversion in endangered catfish, which varies in activity during different reproductive stages and after hormone treatment.

Using finasteride or dutasteride may cause long-lasting erectile dysfunction.

5-alpha-reductase inhibitors can lower prostate cancer risk but may increase high-grade tumors and cause sexual side effects.

Long-term use of a certain medication can worsen erectile function in aged rats by damaging penile muscle cells.

5-alpha-reductase inhibitors may cause a low incidence of erectile dysfunction that decreases over time.

Melatonin may protect inner ear cells from damage by reducing cell death and oxidative stress, potentially treating sudden hearing loss.

A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.

5 alpha-reductase inhibitors can slightly improve symptoms of enlarged prostate but have a high risk of sexual side effects.

Some treatments can stabilize Frontal Fibrosing Alopecia, but more research is needed to find effective treatments, and hair transplants often fail.

A new compound effectively inhibits human 5α-reductase 1.

Men taking 5α-reductase inhibitors for enlarged prostate have a higher chance of experiencing reduced sexual desire and erectile dysfunction.

Dutasteride effectively treats benign prostatic obstruction, improves urinary flow, reduces prostate size, and may prevent prostate cancer, but can cause sexual side effects.

The document concludes that sexual and psychiatric side effects from 5-alpha-reductase inhibitors are reported, but more high-quality research is needed to understand how often they occur.

New treatments for male hypogonadism are effective and should be personalized.

Poor sleep is linked to a higher risk of developing and worsening urinary problems in men.

Dutasteride works better than finasteride for hair loss, with both being safe to use.

Men with benign prostatic hyperplasia are more likely to have metabolic syndrome than those without it.

Different drugs can treat high male hormone levels in women, but they have various effects and some may harm a fetus.

High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.

Prostate cancer prevention includes diet changes, supplements, and medications, with more answers expected soon.

Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.

Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Finasteride, a hair loss drug, can cause sexual side effects like erectile dysfunction in 2.1%-3.8% of users, but these usually go away with time or if the drug is stopped. Despite this, its impact on sexual function is minimal for most men.

Dutasteride treatment in men with mild to moderate COVID-19 reduced viral shedding, inflammation, and recovery time without serious side effects.

Taking 5 alpha reductase inhibitor medication slightly increases the risk of depression, especially as you get older.

Compounds 4, 4b, and 4c effectively inhibit an enzyme linked to testosterone conversion without significant toxicity.