research To Identify the Expression of Intracellular Toll-Like Receptors in Peripheral Blood Mononuclear Cells of Alopecia Areata
Alopecia areata patients have higher levels of certain immune receptors, suggesting new treatment possibilities.
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research The Importance of Dual 5α-Reductase Inhibition in the Treatment of Male Pattern Hair Loss: Results of a Randomized Placebo-Controlled Study of Dutasteride Versus Finasteride
Dutasteride more effective for hair growth, but has more side effects than finasteride.
research An Overview of JAK/STAT Pathways and JAK Inhibition in Alopecia Areata
Blocking JAK/STAT pathways can help treat hair loss from alopecia areata.
research Spironolactone: An Anti-Androgenic and Anti-Hypertensive Drug That May Provide Protection Against the Novel Coronavirus (SARS-CoV-2) Induced Acute Respiratory Distress Syndrome (ARDS) in COVID-19
Spironolactone might help protect against severe lung problems in COVID-19 patients.
research Characterization of Hair Lipid Images by Argon Sputter Etching-Scanning Electron Microscopy
Hair texture changes with age due to varying levels of lipids.
research Efficacy and Safety of Topical Calcipotriol 0.005% Versus Topical Clobetasol 0.05% in the Management of Alopecia Areata: An Intrasubject Pilot Study
Calcipotriol works almost as well as clobetasol for mild to moderate alopecia areata with fewer side effects.
research Oxidative Stress and Alopecia Areata
Oxidative stress may contribute to hair loss in alopecia areata and antioxidants could potentially help as a treatment.
research Artificial Hair Implantation for Hair Restoration
Artificial hair implants can quickly improve looks and life quality, but they have risks like infection and early fiber loss, so more research is needed to confirm their safety and effectiveness.
research Analysis of CTLA-4 Gene +49A/G and CT60 A/G Polymorphisms in Alopecia Areata Patients
CT60 polymorphism might increase the risk of Alopecia Areata.
research M-CSF-Stimulated CD11b+ Myeloid Cells Induce Alopecia Areata in C3H/HeJ Mice
M-CSF-stimulated myeloid cells can cause alopecia areata in mice.
research GABRA2 Alleles Moderate the Subjective Effects of Alcohol, Which Are Attenuated by Finasteride
GABRA2 gene variations impact alcohol response, and hair loss medication finasteride reduces some effects.
research The Role of Micronutrients in Alopecia Areata: A Review
People with alopecia areata often have lower levels of vitamin D, zinc, and folate, but more research is needed to understand if supplements can help treat it.
research A Model for the Turnover of Dihydrotestosterone in the Presence of the Irreversible 5α-Reductase Inhibitors GI198745 and Finasteride
Both drugs lower DHT levels, with GI198745 being more effective.
research Microneedle Arrays Combined With Nanomedicine Approaches for Transdermal Delivery of Therapeutics
Microneedle arrays with nanotechnology show promise for painless drug delivery through the skin but need more research on safety and effectiveness.
research High Auxin and High Phosphate Impact on RSL2 Expression and ROS Homeostasis Linked to Root Hair Growth in Arabidopsis Thaliana
High levels of auxin increase root hair growth by activating RSL2 and producing ROS, while high phosphate levels hinder growth by repressing RSL2.
research Predicting the Permanent Safe Donor Area for Hair Transplantation in Koreans with Male Pattern Baldness According to the Position of the Parietal Whorl
The position of the parietal whorl can predict safe donor areas for hair transplants in Korean men with male pattern baldness.
research Gut Microbiota in Alopecia Areata
The study "Gut microbiota in alopecia areata" examines the gut microbiome of 25 patients with alopecia areata (AA) and finds a disturbed microflora characterized by an overrepresentation of Firmicutes and Proteobacteria, and a reduction in Bacteroidetes, leading to a higher Firmicutes to Bacteroidetes ratio. This pattern is similar to that seen in other conditions like obesity and inflammatory bowel disease. The study also notes a loss of microbial richness and diversity in AA patients. These findings suggest a potential link between gut microbiota disturbances and AA, highlighting the need for further research to understand this relationship and its implications for treatment.
research The Effects of Finasteride on Hair Growth, Hair Cycle Stage, and Serum Testosterone and Dihydrotestosterone in Adult Male and Female Stumptail Macaques
Finasteride increases hair growth, prolongs hair cycle, and lowers dihydrotestosterone levels.
research Effects of the Anti-Androgen Finasteride on 5α-Reduction of Androgens in the Presence of Progesterone in Human Gingival Fibroblasts: Modulatory Actions of the Alkaline Phosphatase Inhibitor Levamisole
Finasteride reduces testosterone conversion, progesterone lessens this, and levamisole enhances finasteride's effect.
research Inhibition of 5α-Reductase Alters Pregnane Metabolism in the Late Pregnant Mare
Inhibiting 5α-reductase increases progesterone levels in late pregnant mares.
research A Randomized Double-Blind, Vehicle-Controlled Bilateral Comparison Study of the Efficacy and Safety of Finasteride 0.5% Solution in Combination with Intense Pulsed Light in the Treatment of Facial Hirsutism
Finasteride and intense pulsed light effectively reduce unwanted facial hair in women, but may not be cost-effective.
research Construction of Regulatory Network for Alopecia Areata Progression and Identification of Immune Monitoring Genes Based on Multiple Machine-Learning Algorithms
Researchers found four genes that could help diagnose severe alopecia areata early.
research Cytoprotective Effects of Paeoniflorin Are Associated with Translocator Protein 18 kDa
Paeoniflorin protects brain cells by involving a specific protein and neurosteroids.
research Prolonged Drug-Induced Hypersensitivity Syndrome/DRESS With Alopecia Areata and Autoimmune Thyroiditis
A severe medication reaction required long treatment and led to hair loss and thyroid issues.
research Vitamin D Status and the Effect of Oral Vitamin D Treatment in Children with Alopecia Areata
Oral vitamin D treatment can help some children with alopecia areata who have vitamin D deficiency.
research Assessing Auditory and Cochlear Function in Alopecia Areata Patients: Exploring the Link to Cochlear Melanocyte Damage
Alopecia areata may be linked to hearing problems, so patients should monitor their hearing.
research Review on Alopecia Areata in the Middle East and Africa: Landscape and Unmet Needs
The Middle East and Africa need better data, treatment consensus, and support for Alopecia Areata.
research Baldness And The Androgen Receptor: The AR Polyglycine Repeat Polymorphism Does Not Confer Susceptibility To Androgenetic Alopecia
AR polyglycine repeat doesn't cause baldness.
research Building and Crossing the Translational Bridge: 2016 Alopecia Areata Research Summit Highlights
The summit aimed to speed up finding treatments for alopecia areata.
research Complications of Cushing's Syndrome: State of the Art
Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.