March 2016 in “Reactions Weekly” A woman experienced hair loss, nail changes, bone marrow suppression, and low blood protein after taking azathioprine.
44 citations
,
August 2004 in “Journal of Investigative Dermatology” A gene deletion in DSG4 causes sparse hair in some Pakistani families.
16 citations
,
June 2022 in “Agronomy” This study found that the application of plant-derived biostimulants, Trainer® and Auxym®, significantly affected various physiological traits in lettuce, but responses varied depending on the cultivar.
9 citations
,
January 2002 in “Dermatology” This study found that cutaneous myxomas showed decreased CD44 expression in follicular epithelial proliferations, which may be related to abnormal hyaluronate accumulation in these lesions.
November 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that exosomes derived from bovine colostrum, compared to those from human stem cells, significantly increased hair follicle growth and regeneration in vitro.
January 2019 in “Spectrum Research Repository (Concordia University)” This study observed that topiramate treatment in female zebrafish may impair genetic transmission to offspring, reducing expression of certain skeletal development-related genes in embryos.
8 citations
,
June 2023 in “Acta Biochimica et Biophysica Sinica” In this study, a subcutaneous injection of recombinant RSPO1 was found to activate hair follicle stem cells and enhance hair regeneration in mice by stimulating the Wnt/β-catenin signaling pathway, suggesting its potential as a treatment for hair loss.
1 citations
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February 2021 in “Animal feed science and technology” This study found that puppies fed organic selenium had better retention of selenium compared to those fed inorganic selenium, with no significant difference in coat quality or hair growth.
83 citations
,
May 2011 in “European Journal of Dermatology” This review discusses the role of corneodesmosin in skin and hair follicle integrity, with mentions of its link to hypotrichosis simplex and peeling skin disease, and reports no new results.
47 citations
,
September 2002 in “Journal of Bone and Mineral Research” This study found that a specific VDR amino acid substitution in children with hereditary vitamin D-resistant rickets disrupts ligand binding and gene activation but does not impair hair follicle development.
30 citations
,
November 1992 in “The Journal of Dermatology” This review discusses the roles of filaggrin and trichohyalin in keratinocyte differentiation and reports no new results; the authors introduce possible hybrid granules in tongue epithelia.
51 citations
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August 2021 in “Turkish Journal of Medical Sciences” This review concluded that monoclonal antibodies are currently the most effective treatment for COVID-19, with potential efficacy of high-titer convalescent plasma when used early, while multiple other drugs require further evaluation to determine their effectiveness.
12 citations
,
August 2011 in “Asian-Australasian Journal of Animal Sciences” This study found that polymorphisms in the KAP8.1 gene were significantly associated with cashmere weight, length, and guard hair length in Chinese Inner Mongolian Cashmere goats, but not with fibre diameter.
10 citations
,
November 2017 in “Journal of Investigative Dermatology” In this study, researchers identified a novel homozygous variant in the FAM83G gene responsible for autosomal recessively inherited palmoplantar keratoderma with curly hair in a consanguineous Pakistani family, suggesting FAM83G plays a crucial role in skin and hair homeostasis.
52 citations
,
February 2006 in “Archives of Dermatology” This case report describes a 25-year-old woman with widespread lichen planus who did not respond to multiple systemic treatments, including antihistamines, hydroxychloroquine sulfate, and corticosteroids.
1 citations
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August 2016 in “Dermatology - Open Journal” In this study, the researchers found that optic atrophy 1 (OPA1) is involved in the transition between filamentous and rounded mitochondria in hair follicle dermal papilla cells, potentially influencing cellular energy dynamics.
140 citations
,
August 2010 in “Pigment Cell & Melanoma Research” This article discusses mouse genetic studies to explore factors influencing melanogenesis, highlighting pH and cysteine's roles, and proposes a hypothesis for human hair color diversity; it reports no new results.
24 citations
,
September 2018 in “Journal of Materials Science: Materials in Medicine” In this study using rabbits, HA2 hydrogels made from cross-linked hyaluronic acid and polysaccharide promoted wound healing better than other treatments, reducing inflammation and scar formation.
15 citations
,
June 2019 in “eLife” This study identified Activin A and follistatin as key regulators of hair cell differentiation in the mammalian auditory sensory epithelium, with Activin A signaling influencing the timing and pattern of cell differentiation.
57 citations
,
January 1987 in “Journal of Biological Chemistry” This study identified and sequenced several keratin cDNA clones showing distinct expression patterns in mouse epithelia, with in situ hybridization highlighting differences in keratin distribution between normal and hyperproliferative tissues.
15 citations
,
April 2017 in “Cell Stem Cell” This study found that glioblastoma cancer stem cells avoid immune suppression by downregulating TLR4, and restoring TLR4 signaling may reduce tumor growth and self-renewal.
8 citations
,
April 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” This study identified biallelic variants in the LSS gene as a possible genetic cause of palmoplantar keratoderma-congenital alopecia syndrome type 2, highlighting the role of cholesterol synthesis in skin cornification.
4 citations
,
October 2014 in “Springer eBooks” This chapter reviews the roles of ethylene and auxin in seedling growth and development and reports no new experimental results; it highlights recent studies on their mechanistic crosstalk.
2 citations
,
June 2020 in “Research Square (Research Square)” This study demonstrated that the antiandrogen drug enzalutamide may reduce TMPRSS2 levels in human lung cells and mouse lungs, supporting its potential as a COVID-19 treatment option.
1 citations
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January 2021 in “Research Square (Research Square)” This study found that the antiandrogens enzalutamide and bicalutamide reduced SARS-CoV-2 entry and infection in human lung cells by lowering TMPRSS2 levels, suggesting their potential as COVID-19 treatments and supporting clinical trials.
September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” This study identified a mutation in the CST6 gene linked to a rare syndrome with symptoms affecting hair and skin, revealing cystatin M/E's role in maintaining epidermal homeostasis and hair follicle development.
October 2004 in “Kafrelsheikh Veterinary Medical Journal” In this study, buffalo calves fed only corn silage showed deficiencies in copper, zinc, selenium, and vitamin A, along with improved physiological conditions after dietary supplementation and treatment.
December 2020 in “Benha Journal of Applied Sciences” This study found that patients with acne vulgaris had significantly higher serum levels of betatrophin compared to healthy controls, suggesting it may be an independent predictor of acne severity and vulnerability.
74 citations
,
October 2012 in “The American Journal of Human Genetics” This study found that loss-of-function mutations in the HOXC13 gene cause autosomal-recessive pure hair and nail ectodermal dysplasia, emphasizing its role in hair and nail development.
37 citations
,
March 2010 in “British Journal of Dermatology” Oestrogen and thyrotropin-releasing hormone affect prolactin and its receptor in human skin and hair, suggesting new treatment options for related conditions.