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This article discusses the various administration methods and considerations for testosterone replacement therapy, highlighting the importance of individualized therapeutic monitoring and potential adverse effects, but reports no new clinical results.

This commentary discusses the crucial role of the alternative splicing factor Esrp1 in maintaining skin barrier function and its association with skin diseases like atopic dermatitis and psoriasis, but reports no new clinical results.

This study used cryo-electron microscopy to reveal the structural mechanisms by which TRPV6 and TRPV3 ion channels open, close, and are regulated, providing insights for potential future research.

This review discusses the regulation of the MiT-TFE family transcription factors, particularly TFEB, through phosphorylation-mediated subcellular localization and reports no new clinical results.

Ets2 gene is crucial for placental development in mice.

This study found that increased intracellular expression of thymosin β4 is necessary and sufficient to induce PAI-1 gene expression in endothelial cells, potentially mediated through Ku80 as a novel receptor.

This study found that CPA-loaded nanoparticles, particularly SLN formulations, increased CPA epidermal penetration compared to a conventional cream and may reduce side effects in treating androgen-dependent conditions.

This case report describes a 53-year-old woman with a rare presentation of trichostasis spinulosa on her breast and abdomen, featuring itchy, comedo-like lesions. Dermoscopy revealed diagnostic features that may eliminate the need for a biopsy, highlighting the potential for non-invasive diagnosis in such cases.

In this study, the authors observed that testosterone therapy shortened the QTc interval and normalized T-wave morphology in men with acquired LQTS or TdP linked to hypogonadism, suggesting testosterone may be helpful in treatment.

This study found that V-ATPase plays a role in the acidification of vas deferens fluid under the influence of testosterone in orchidectomized rats.

This study found that exposure to certain pesticides may be associated with delayed sexual maturation in adolescent males.

This article lists the clinically important interactions and skin reactions of several drugs and substances, including THA, FK506, tamoxifen, tamsulosin, tartrazine, tea tree oil, temazepam, and temozolomide, but provides no new clinical results.

This study analyzed safety data for semaglutide, liraglutide, and tirzepatide from the EudraVigilance database, identifying potential safety signals not listed in current SmPCs, such as optic ischemic neuropathy and pancreatitis, underscoring the importance of ongoing pharmacovigilance.

This chapter discusses androgen receptors and protein synthesis in the prostate, reporting that DHT-dependent receptor protein translocation increases protein-synthesizing activity after androgen injection in rat models.

This study reports that TFM-4AS-1, a selective androgen receptor modulator, promoted bone and muscle growth with reduced effects on reproductive organs in ovariectomized rats.

This review examines existing research on transdermal testosterone for treating hypoactive sexual desire disorder, suggesting it improves female sexual function with minimal side effects but highlights the need for more long-term safety data.

Rat hair follicle stem cells have functional oxytocin receptors, useful for studying neuropsychiatric disorders.

In this study, patients with testicular feminization syndrome showed limited anabolic responsiveness to dihydrotestosterone, potentially due to reduced affinity of nuclear receptor sites for androgenic steroids rather than defective testosterone conversion.

This study developed and validated ultraviolet spectrophotometric and reversed phase high performance liquid chromatographic methods for simultaneously estimating Tamsulosin and Finasteride in tablet form, showing statistical validation and effectiveness in pharmaceutical analysis.

The researchers reported that thymosin beta 4 promotes hair growth in various rat and mice models by influencing follicle stem cell growth, migration, and differentiation.

A deep learning model was developed to help diagnose trichothiodystrophy by analyzing hair patterns.

This preliminary study suggests that baseline central serotonin turnover, indicated by CSF 5-HIAA levels, may influence treatment response to serotonin re-uptake inhibitors in women with trichotillomania.

This study suggests that tissue transglutaminase (TG2) may play a role in sebum production by regulating autophagy in sebaceous glands, offering potential targets for dermatological interventions.

This report describes a case of a patient with Sjogren's syndrome who experienced multiple episodes of aseptic meningitis linked to taking trimethoprim-sulfamethoxazole and trimethoprim alone.

In this study, transgenic mice overexpressing the SSAT gene were highly sensitive to polyamine analogues, leading to severe liver changes and high mortality rates after treatment.

This study suggests that KRTAP2-3 may serve as a novel biomarker to identify cells in the polyaneuploid cancer cell state, which is linked to therapy resistance and poor prognosis in prostate cancer.

In this study of a TRPS type I patient, many genes related to keratin and hair development were down-regulated in balding scalp areas, providing new insights into TRPS and hair morphogenesis.

The researchers reported two brothers with a new variant of X-linked trichothiodystrophy associated with an RNF113A gene mutation, highlighting features such as intellectual disability and growth failure, but without previously reported endocrinological or genital abnormalities, underlining the importance of genetic counseling for such variants.

This case report identifies a novel mutation in a patient with trichorhinophalangeal syndrome 1 and reduced TRPS 1 protein expression in hair follicle tissues compared to normal subjects.