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This review explores the use of skin penetration enhancers like Transcutol® in various formulation systems, discussing their mechanisms and effectiveness in improving transdermal drug delivery without breaching the skin.

In this report, an 18-year-old female with trichotillomania was successfully treated using the glutamate modulator n-acetylcysteine.

This study involved using smartphone applications and low-cost trichoscopy devices to assess various hair and scalp conditions, with diagnoses confirmed through detailed imaging during remote consultations and in-person evaluations.

This study reports that daily topical application of a 0.05% tretinoin solution can eliminate the hair plugs and symptoms associated with trichostasis spinulosa.

This case report details a 28-year-old male who developed trichotillomania following a traumatic brain injury, highlighting diagnostic challenges in distinguishing overlapping psychiatric and compulsive behaviors, and underscores the importance of a comprehensive, multidisciplinary treatment approach.

Early diagnosis and treatment of TPP can prevent complications.

This article presents a case of trichostasis spinulosa, a common but often unrecognized disorder, diagnosed through dermoscopic examination of black macules revealing bundled vellus hairs, with the patient declining treatment.

In this report, researchers describe a 13-month-old with neurodevelopmental disorder NEDESBA, confirming a TRAPPC4 gene mutation as the cause after excluding biotinidase deficiency, highlighting the importance of molecular testing for accurate diagnosis in overlapping metabolic and genetic conditions.

This study provides a comprehensive review of trichotillomania, focusing on its clinical symptoms, etiology, diagnostics, and treatment methods, while also addressing serious complications like trichobezoars and Rapunzel Syndrome.

This study developed dissolving microneedles using specific polymers for transdermal delivery of rizatriptan benzoate, demonstrating improved drug skin penetration and significant alleviation of migraine symptoms in vivo compared to passive diffusion, suggesting potential advantages over conventional treatment methods for acute migraine.

This study identified a specific hemizygous intronic variant in the MBTPS2 gene associated with IFAP syndrome in a patient, revealing exon skipping and reduced normal transcript expression through long-read RNA sequencing.

This article reviews numerous drug reactions and interactions for various medications and does not present new research findings.

This review discusses treatment options for trichotillomania, focusing on cognitive-behavioral interventions and promising developments in combined pharmacotherapy and therapy approaches, but reports no new findings.

This study reported that platelet-rich plasma injections led to only temporary improvement in vellus hair characteristics in temporal triangular alopecia, suggesting it may not be an effective long-term treatment.

This review discusses trichotillomania treatments, highlighting that habit reversal training shows promise for children and adolescents, although further research is needed, as existing literature on this age group is sparse.

In this study, hair shafts from trichothiodystrophy patients with ERCC2 mutations revealed abnormal cuticle structures and protein imbalances compared to normal hair shafts.

This study found that deficiency in TLR3/TRIF signaling reduced inflammation and protected mice against postoperative ileus, suggesting potential for TLR3 antagonism as a preventive approach in humans.

This review discusses the clinical features of trichotillomania and the challenges in its diagnosis and treatment, reporting no new clinical findings while highlighting the need for specialized therapy and better therapeutic options.

This study found that hypogonadism in men can be a reversible risk factor for torsades de pointes (TdP), with testosterone replacement potentially preventing TdP recurrence.

This review outlines the phytochemical composition and pharmacological potential of Tridax procumbens, a plant traditionally used in various regions for its purported medical benefits, including antioxidant, antimicrobial, and anti-inflammatory effects, among others.

This study found that TRPV3 ion channels on human epidermal keratinocytes suppress cell proliferation, induce cell death, and trigger a proinflammatory response, suggesting a role in cutaneous inflammatory processes.

This commentary discusses the crucial role of the alternative splicing factor Esrp1 in maintaining skin barrier function and its association with skin diseases like atopic dermatitis and psoriasis, but reports no new clinical results.

Tiger tail banding and hair abnormalities are reliable indicators for diagnosing trichothiodystrophy.

This study found that intrathyroidal injection of autologous platelet-rich plasma improved thyroid function and symptoms in hypothyroidism patients, without adverse events over one year.

In this case-control study, researchers did not find genome-wide significant genetic variants for trichotillomania, but cases had higher polygenic risk for psychiatric disorders and certain neuropsychiatric-associated copy number variants.

This study evaluated the phytochemical properties and in-vitro anti-fungal activity of Tridax procumbens but reports no new clinical results.

This review explores the role of transient receptor potential vanilloid channels in the pathogenesis of osteoarthritis but reports no new clinical results.

This consensus report provides detailed recommendations for using Polynucleotides Highly Purified Technology™ in aesthetic skin rejuvenation, highlighting its potential as a biostimulatory booster for face and body revitalization.

The authors concluded that newly synthesized N-acyl-L-tryptophanyl-isoleucine amides showed high anxiolytic activity in animal models, comparable to diazepam, through interaction with the TSPO receptor.

This study found that local therapy with trichoriboside and trichosaccharide significantly increased cAMP levels in hair follicles of men with androgenic alopecia, with trichoriboside showing greater activity.