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Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

Metformin improves hair growth and menstrual frequency in women with PCOS and hirsutism.

Apigenin, found in plants and vegetables, has many health benefits, including anti-inflammatory, antioxidant, and anticancer effects.

Deleting the Far2 gene in mice causes sebaceous gland issues and patchy hair loss.

Hidradenitis suppurativa may be related to hormones and patients often have metabolic disorders; more research is needed to understand this connection.

Polycystic ovary syndrome increases the risk of diabetes, heart disease, and endometrial cancer, and requires early treatment to manage these risks.

Acitretin is effective for severe psoriasis and can be used long-term due to no immunosuppression, but must be carefully monitored for side effects and is not for pregnant women.

Acne is an important sign of androgen excess disorders in women.

The document concludes that a high-protein, low-carb diet can lead to significant weight loss but requires caution and further research.

The guidelines suggest lifestyle changes, diet adjustments, and personalized medication to manage dyslipidemia and reduce heart disease risk.

Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.

There is no cure for myotonic dystrophy type 1, so treatment focuses on managing symptoms and complications.

NF-κB signaling is crucial in many diseases and can be targeted for new treatments.

Some skin conditions, like psoriasis and early-onset baldness, may indicate metabolic syndrome, and others are linked to diabetes risk and cardiovascular issues.

The conclusion suggests a new acne treatment that controls bacteria by reducing water in the skin's pores using sugar-like substances.

Linoleic acid (Vitamin F) can help protect against the harmful effects of acrylamide.

A man's health improved after treating his undiagnosed adrenal insufficiency, which caused fatigue and weight loss.

Cosmeceuticals may benefit skin health but need more research for efficacy and safety confirmation.

Statins may help treat PCOS by lowering androgen levels and improving cholesterol.

Isoflavone may help manage PCOS symptoms, but its effectiveness is uncertain.

Spironolactone improved blood vessel function and cholesterol levels in non-obese women with PCOS.

Coriander seed oil is safe for healthy adults at up to 600 mg per day.

High doses of Lepidium sativum seed extract are toxic and should be used with caution.

Mesenchymal stem cells could help treat aging-related diseases better than current methods.

Obesity is linked to many gastrointestinal diseases and needs more research for treatment development.

SLE and DM can coexist but are rare and need careful evaluation.

New treatments for male hypogonadism are effective and should be personalized.

The 2023 guideline for PCOS suggests using updated diagnostic criteria, assessing related health risks, and recommends lifestyle changes and specific treatments for symptoms and fertility issues.

Men with early hair loss may have higher health risks similar to women with PCOS.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.