The study found that conditioned medium from placental cells and sub-cultured placental tissue promoted angiogenesis in HUVECs, with early pregnancy cells showing more significant effects than those from full-term pregnancy.
May 2025 in “Indian Dermatology Online Journal” This case report highlighted two atypical childhood alopecia cases: congenital atrichia without papules and Bjornstad syndrome with alopecia areata; emphasizing diagnostic challenges, notably the absence of keratotic papules usually associated with congenital atrichia and the presence of alopecia areata in Bjornstad syndrome.
73 citations
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January 2004 in “Journal of the American Academy of Dermatology” Immunocompromised patients can develop skin and hair issues due to a virus.
205 citations
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April 2005 in “Journal of Investigative Dermatology” This study describes a system for generating hair follicles from dissociated cells in mice, suggesting that successful development requires a foundational epithelial platform.
54 citations
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November 1994 in “Differentiation” This study found that trichohyalin is expressed in various normal and pathological epithelia beyond hair follicle cells, where it is uniquely associated with filaggrin, suggesting a specific role in aggregating K6/K16-containing intermediate filaments.
7 citations
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November 2022 in “Actas Dermo-Sifiliográficas” This study reviewed the usefulness of trichoscopy in diagnosing and monitoring alopecia areata, noting that the technique identifies specific hair features like yellow and black dots, which are linked to the disease's chronic nature and treatment response.
36 citations
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January 1994 in “Cell and Tissue Research” January 2026 in “Indian Journal of Ophthalmology - Case Reports” In this study, a rare case of a trichilemmal cyst in a 6-year-old's upper eyelid was observed; it was identified through histopathological examination after excision, highlighting the importance of considering trichilemmal cysts in atypical pediatric eyelid swellings.
1 citations
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January 2018 in “Indian journal of dermatopathology and diagnostic dermatology” This review discusses the use of trichoscopy as a valuable diagnostic and prognostic tool for various hair and scalp disorders, reporting no new clinical results.
5 citations
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October 2012 in “Expert Review of Dermatology” This article reviews trichoscopic techniques for diagnosing common hair loss conditions and presents a revised algorithm for identifying specific features of cicatricial and noncicatricial alopecia, but reports no new clinical results.
March 2021 in “CRC Press eBooks” This article reviews the complexities and challenges in hair transplant procedures, emphasizing the role of micro-inflammation and the usefulness of trichoscopy for detecting complications, and reports no new clinical results.
December 2023 in “Portuguese journal of dermatology and venereology” This study found that trichoscopic examination can effectively differentiate between alopecia areata and trichotillomania, as specific features such as black dots and exclamation marks favor alopecia areata while hair breaking at various lengths and several unique patterns are exclusive to trichotillomania.
17 citations
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December 1994 in “International Journal of Dermatology” This article reports no new clinical findings but discusses two rare dermatological conditions, trichostasis spinulosa and eruptive vellus hair cysts, and their simultaneous occurrence.
May 2022 in “Experimental dermatology” In this study, hair shafts from trichothiodystrophy patients with ERCC2 mutations revealed abnormal cuticle structures and protein imbalances compared to normal hair shafts.
July 2021 in “Indian journal of dermatopathology and diagnostic dermatology” In this study, researchers documented several trichoscopic features that were statistically significant indicators of alopecia and scalp disorders compared to healthy controls.
2 citations
,
January 1993 This study found that human trichohyalin has a unique protein sequence potentially contributing to at least three important functions in hair follicle and epidermal cells.
27 citations
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May 2011 in “Journal of Investigative Dermatology” TCHHL1 is a protein important for hair growth, found in hair follicles.
1 citations
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March 2022 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia” This study found that trichoscopy is a useful tool in differentiating between alopecia areta and trichotillomania on the eyebrows based on distinct hair and follicle features.
March 2023 in “Journal of skin and stem cell” This study concluded that trichoscopy is a reliable, non-invasive, and faster diagnostic method for ambiguous cases of alopecia.
7 citations
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January 2013 in “Dermatology Research and Practice” This review discusses the usefulness of trichoscopy in diagnosing and managing scalp and hair disorders, reporting it as a valuable tool for linking clinical and histological findings.
January 2017 in “대한미용학회지” This study observed that hair follicle cuticular cells undergoing keratinization were significantly thicker than those in a normal hair shaft, due to incomplete loss of cytosol.
September 2022 in “TURKDERM” This article reports an unprecedented case of trichofolliculoma in the gluteal area, previously unreported in English literature.
35 citations
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September 2003 in “Archives of dermatology” This study proposed that the tiger tail phenomenon in trichothiodystrophy hair is caused by regular undulations of hair fibers, altering the optical properties seen under polarized light.
January 2024 in “Lecture notes in networks and systems” In this study, a system was developed utilizing advanced image processing to analyze hair and scalp conditions, aiding professionals in diagnosing diseases like alopecia and monitoring treatment by extracting and comparing key parameters from microscopic images.
This study demonstrates that the trichohyalin gene is located at chromosomal region 1q21, where several other genes related to epidermal differentiation also map.
January 2023 in “Skin appendage disorders” In this study, trichoscopy revealed hair shaft abnormalities similar to those seen in alopecia areata and chemotherapy-induced alopecia in patients over 12 months following hair restoration surgery.
108 citations
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October 2003 in “Journal of biological chemistry/The Journal of biological chemistry” This study documents that trichohyalin acts as a multi-functional cross-bridging protein in the inner root sheath of mouse hair follicles, enhancing mechanical strength by linking keratin filaments to the cell envelope.
January 2023 in “Journal of Clinical and Diagnostic Research” This study in Chennai, India, found that while some trichoscopic patterns are specific, many overlap across different scalp dermatoses, highlighting the importance of dermatologists staying informed about the latest findings.
178 citations
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December 2011 in “Journal of Dermatological Case Reports” This review discusses the application of trichoscopy in diagnosing various hair and scalp diseases and reports no new clinical results; the authors emphasize its role as a non-invasive diagnostic tool.
18 citations
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March 2009 in “Experimental Dermatology” This study suggests that pilomatricoma can differentiate towards various hair follicle structures, including hair matrix, hair cortex, follicular infundibulum, outer root sheath, and hair bulge.