research Physiological Functions of PP2A: Lessons from Genetically Modified Mice
Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.
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research The Keratins of the Human Beard Hair Medulla: The Riddle in the Middle
Human beard hair medulla contains a unique and complex mix of keratins not found in other human tissues.
research Mutant Laboratory Mice With Abnormalities in Hair Follicle Morphogenesis, Cycling, and Structure: Annotated Tables
Mutant mice help researchers understand hair growth and related genetic factors.
research Development and Progression of Alopecia in the Vitamin D Receptor Null Mouse
Mice without the vitamin D receptor gene lose hair due to disrupted hair follicle cycles.
research Tumor Regression Predicts Higher Risk of Sentinel Node Involvement in Thin Cutaneous Melanomas
Shrinking skin cancer increases the chance of cancer in nearby lymph nodes.
research Dynamic Signals for Hair Follicle Development and Regeneration
Certain signals and genes play a key role in hair growth and regeneration, and understanding these could lead to new treatments for skin regeneration.
research Age-Associated Inflammation Connects RAS-Induced Senescence to Stem Cell Dysfunction and Epidermal Malignancy
Older skin has higher cancer risk due to inflammation and stem cell issues.
research Induction of Transforming Growth Factor-Beta 1 by Androgen Is Mediated by Reactive Oxygen Species in Hair Follicle Dermal Papilla Cells
Androgens increase a growth factor in hair cells by creating reactive oxygen species, and antioxidants might help treat hair loss.
research Tcf3 Promotes Cell Migration and Wound Repair Through Regulation of Lipocalin 2
Tcf3 helps cells move and heal wounds by controlling lipocalin 2.
research The Functional Diversity of Epidermal Keratins Revealed by the Partial Rescue of the Keratin 14 Null Phenotype by Keratin 16
K16 can partially replace K14 but causes hair loss and skin issues.
research The Management of Postacne Scarring
New treatments for acne scars are safer and more effective because we understand the causes better.
research The Spectrum of Scarring in Craniofacial Wound Repair
Wounds on the face usually heal with scars, but understanding how some wounds heal without scars could lead to better treatments.
research Identification of Ectodysplasin Target Genes Reveals the Involvement of Chemokines in Hair Development
Chemokine signaling is important for hair development.
research Some Observations on Vitamin Metabolism in Germ-Free Rats
Germ-free rats need biotin for growth and have different vitamin metabolism compared to regular rats.
research Heparan Sulfate Regulates Hair Follicle and Sebaceous Gland Morphogenesis and Homeostasis
Heparan sulfate is important for hair growth, preventing new hair formation in mature skin, and controlling oil gland development.
research Effect of Topical Application of Raspberry Ketone on Dermal Production of Insulin-Like Growth Factor-I in Mice and on Hair Growth and Skin Elasticity in Humans
Raspberry ketone may help grow hair and improve skin elasticity.
research Scalp Melanoma: Distinctive High-Risk Clinical and Histological Features
Scalp melanomas are more dangerous and often missed, needing earlier detection.
research Surgical Approach to Adolescent Obesity
Bariatric surgery may help severely obese teenagers but has risks and requires careful patient selection and long-term care.
research Glucocorticoid Receptor Mutants Demonstrate Increased Motility Inside the Nucleus of Living Cells: Time of Fluorescence Recovery After Photobleaching Is an Integrated Measure of Receptor Function
Certain defective glucocorticoid receptor mutants move faster inside cell nuclei and work less effectively.
research The Hair Follicle: An Underutilized Source of Cells and Materials for Regenerative Medicine
Hair follicles are valuable for regenerative medicine and wound healing.
research Ectodysplasin Research: Where to Next?
Future research on ectodysplasin should explore its role in diseases, stem cells, and evolution, and continue developing treatments for genetic disorders like hypohidrotic ectodermal dysplasia.
research Enzyme Replacement Therapy Ameliorates Multiple Symptoms of Murine Homocystinuria
Enzyme replacement therapy improved multiple symptoms of homocystinuria in mice.
research High-Content Drug Screening for Rare Diseases
High-content screening is useful for finding new treatments for rare diseases and has led to FDA-approved drugs.
research Self-Organizing Hair Peg-Like Structures From Dissociated Skin Progenitor Cells: New Insights for Human Hair Follicle Organoid Engineering and Turing Patterning in an Asymmetric Morphogenetic Field
Researchers created early-stage hair-like structures from skin cells, showing how these cells can self-organize, but more is needed for complete hair growth.
research Loose Anagen Syndrome And Loose Anagen Hair
Loose Anagen Syndrome causes easy-to-pull, thin hair, mainly in young girls, and improves with age.
research Integrative Analysis of Methylome and Transcriptome Reveals the Regulatory Mechanisms of Hair Follicle Morphogenesis in Cashmere Goat
DNA methylation and long non-coding RNAs are key in controlling hair growth in Cashmere goats.
research Nonhuman Primate Dermatology: A Literature Review
The document concludes that veterinary dermatologists need more experience and a better approach to treating skin diseases in nonhuman primates.
research Ovarian Hormones and Adrenal Androgens During a Woman's Life Span
Women's ovarian hormones and adrenal androgens change throughout life, affecting hair loss and health.
research Symmetry Breaking of Tissue Mechanics in Wound-Induced Hair Follicle Regeneration of Laboratory and Spiny Mice
Tissue stiffness affects hair follicle regeneration, and Twist1 is a key regulator.
research Overview of Ultrasound Imaging Applications in Dermatology
Ultrasound is a useful, non-invasive tool in dermatology for diagnosing skin conditions and guiding treatments, but it has some limitations.