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A boy with a rare skin condition and kidney disease improved with cyclosporine after steroids failed, suggesting a new treatment approach.

Involucrin helps strengthen the inner parts of human hair.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.

The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

Mice without Vitamin D receptors have hair growth problems because of issues in the hedgehog signaling pathway.

Three new types of a skin blistering disease were found, caused by specific gene mutations.

New skin substitutes for treating severe burns and chronic wounds are being developed, but a permanent solution for deep wounds is not yet available commercially.

New gene identification techniques have improved the understanding and classification of inherited hair disorders.

A 72-year-old man had severe fatigue, weight loss, and frequent loose stools.

The study suggests that a new protease inhibitor can make hair harder to pull out, potentially reducing hair loss.

ILK is essential for skin development, pigmentation, and healing.

The top research priorities for congenital ichthyosis include long-term side effects of oral retinoids, best topical treatments, and treatments for itch and hair loss.

A 66-year-old woman with skin lesions and other symptoms improved after treatment for porphyria cutanea tarda.

Mimicking growth factors in a topical solution can prolong hair growth phase and reduce hair loss without side effects.

A woman's nail separation was likely caused by poor blood flow, and a treatment for similar conditions might help.

Human hair proteins vary by individual, body site, and ethnicity, useful for forensics.

Finasteride increases hair density in female androgenetic alopecia, but individual results may vary.

TCF/Lef1 is essential for skin barrier function by regulating lipid metabolism.

A boy's growth and immune problems were caused by a new mutation in the STAT5B gene.

The C-terminal tail of AHF/trichohyalin is essential for organizing keratin filaments in keratinocytes.

Not having enough or having too much of the protein Grainyhead-like 3 leads to various developmental problems.

A 37-year-old male with severe skin and internal issues has a rare inherited skin condition called dystrophic epidermolysis bullosa.

Targeting the skin's endocannabinoid system could help treat skin disorders.

Hormones and signaling pathways control sebaceous gland function and could help treat acne.

High glycine–tyrosine keratin-associated proteins help make hair strong and maintain its shape.

sPLA2-X is crucial for normal hair growth and follicle health.

Type I interferons play a key role in the development of various skin diseases.

Mutations in NIPAL4 cause skin issues by disrupting lipid layers, but some improvement is seen with topical treatment.