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Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.

Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.

Hormone therapy and surgeries for transgender individuals affect their skin and hair, requiring specific dermatologic treatments and respectful care.

RACB in barley is crucial for cell polarity and nucleus positioning, aiding fungal infection.

Injectables can feminize or masculinize a transgender person's face, but more research is needed for best practices.

Scalp cooling can help prevent chemotherapy-induced hair loss with a 50-90% success rate and is safe for patients.

Genetically-altered adult stem cells can help in wound healing and are becoming crucial in regenerative medicine and drug design.

Researchers developed a model that shows hair follicles increase skin absorption of caffeine by 20%.

Graphene oxide and indole-3-acetic acid together inhibit root growth in Brassica napus L. by affecting multiple plant hormone pathways.

Activating Notch in adult skin causes T cells and neural crest cells to gather, leading to skin issues.

ROOT HAIR SPECIFIC 10 (RHS10) reduces the length of root hairs in Arabidopsis plants.

Hormone therapy affects hair growth in transgender individuals, with testosterone potentially causing hair loss in trans men and estrogen reducing facial/body hair in trans women; treatment options vary.

Regulatory T cells are essential for normal and improved wound healing in mice.

Meis1 is crucial for skin health and tumor development.

The document concludes that careful design of genetic fate mapping experiments is crucial for accurate cell lineage tracing in mice.

A protein called PLC2 is important for the growth and development of plant roots influenced by auxin.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

Further research is needed to improve hair regeneration using stem cells and nanomaterials.

NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.

New methods like nanoparticles and microneedles show promise for better skin drug delivery, especially for hair disorders.

Researchers found a safe and effective way to pick genetically modified skin cells with high growth potential using CD24.

Mutations in the HEPHL1 gene cause abnormal hair and cognitive issues.

Applying a special DNA plasmid to the skin can make it thicker and stronger.

The method safely and efficiently delivers genes to the skin but may not work for conditions needing high levels of gene products.

The review highlights the need for more research on transgender dermatology, the role of dermatologists in gender affirmation, and the effects of hormone therapy on skin and hair.

Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.

The transfollicular route shows promise for noninvasive, targeted drug delivery but needs more research.

Understanding how epigenetic regulation affects stem cells is key to cancer insights and new treatments.

HPV genes in mice improve ear tissue healing by speeding up skin growth and repair.

Genetic counselors should be culturally skilled and aware of transgender patients' unique health risks and needs.