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    Glossary Transforming Growth Factor

    proteins regulating cell growth, differentiation, and immune responses

    Transforming Growth Factor (TGF) refers to a group of proteins that play crucial roles in regulating cell growth, differentiation, and immune responses. There are two main types, TGF-α and TGF-β, with TGF-β being particularly important in processes like wound healing, fibrosis, and the regulation of the immune system. These factors are significant in both normal physiological processes and in the development of diseases such as cancer and fibrosis.

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    1. Transforming growth factor-β in stem cells and tissue homeostasis Bone Research · 2018 · 245 citations
    2. Differential Expression of Fibromodulin, a Transforming Growth Factor-β Modulator, in Fetal Skin Development and Scarless Repair American Journal of Pathology · 2000 · 168 citations
    3. Transforming Growth Factor-β Receptor Type I and Type II Expression During Murine Hair Follicle Development and Cycling Journal of Investigative Dermatology · 1997 · 148 citations
    4. Ontogenetic Transition in Fetal Wound Transforming Growth Factor-β Regulation Correlates with Collagen Organization American Journal of Pathology · 2003 · 109 citations
    5. Age-Related Loss of Innate Immune Antimicrobial Function of Dermal Fat Is Mediated by Transforming Growth Factor Beta Immunity · 2018 · 96 citations
    6. Towards Dissecting the Pathogenesis of Retinoid-Induced Hair Loss: All-Trans Retinoic Acid Induces Premature Hair Follicle Regression (Catagen) by Upregulation of Transforming Growth Factor-β2 in the Dermal Papilla Journal of Investigative Dermatology · 2005 · 92 citations
    7. Control of Human Hair Growth by Neurotrophins: Brain-Derived Neurotrophic Factor Inhibits Hair Shaft Elongation, Induces Catagen, and Stimulates Follicular Transforming Growth Factor β2 Expression Journal of Investigative Dermatology · 2005 · 64 citations
    8. Differential effects of caffeine on hair shaft elongation, matrix and outer root sheath keratinocyte proliferation, and transforming growth factor‐β2/insulin‐like growth factor‐1‐mediated regulation of the hair cycle in male and female human hair follicles<i>in vitro</i> British Journal of Dermatology · 2014 · 60 citations
    9. Induction of transforming growth factor-beta 1 by androgen is mediated by reactive oxygen species in hair follicle dermal papilla cells Journal of Biochemistry and Molecular Biology · 2013 · 56 citations
    10. Fibromodulin-Deficiency Alters Temporospatial Expression Patterns of Transforming Growth Factor-β Ligands and Receptors during Adult Mouse Skin Wound Healing PLOS ONE · 2014 · 32 citations
    11. P311 induces the transdifferentiation of epidermal stem cells to myofibroblast-like cells by stimulating transforming growth factor β1 expression Stem Cell Research & Therapy · 2016 · 24 citations
    12. Ginsenoside F2 Reduces Hair Loss by Controlling Apoptosis through the Sterol Regulatory Element-Binding Protein Cleavage Activating Protein and Transforming Growth Factor-β Pathways in a Dihydrotestosterone-Induced Mouse Model Biological & Pharmaceutical Bulletin · 2014 · 22 citations
    13. Human hair follicle stem cell differentiation into contractile smooth muscle cells is induced by transforming growth factor-β1 and platelet-derived growth factor BB Molecular Medicine Reports · 2013 · 19 citations
    14. An investigation of crosstalk between Wnt/β-catenin and transforming growth factor-β signaling in androgenetic alopecia Medicine · 2016 · 18 citations
    15. Transforming Growth Factor-??, Smad, and Collagen Expression Patterns in Fetal and Adult Keratinocytes Plastic and Reconstructive Surgery · 2007 · 16 citations
    16. Protopanaxatirol type ginsenoside Re promotes cyclic growth of hair follicles via inhibiting transforming growth factor β signaling cascades Biochemical and Biophysical Research Communications · 2016 · 14 citations
    17. Expression of transforming growth factor-beta (TGF-beta 1) and insulin-like growth factor II (IGF-II) messenger RNA in the developing subcutaneous tissue (SQ) of the fetal pig. PubMed · 1992 · 11 citations
    18. trans-3,4'-Dimethyl-3-hydroxyflavanone, a Hair Growth Enhancing Active Component, Decreases Active Transforming Growth Factor .BETA.2 (TGF-.BETA.2) through Control of Urokinase-Type Plasminogen Activator (uPA) on the Surface of Keratinocytes Biological and Pharmaceutical Bulletin · 2008 · 10 citations
    19. Expression Patterns of Gli-1, Pleckstrin Homology-Like Domain, Family A, Member 1, Transforming Growth Factor-β1/β2, and p63 in Sebaceous and Follicular Tumors Annals of Dermatology · 2014 · 8 citations
    20. Discovery of 7-Methoxy-6-[4-(4-methyl-1,3-thiazol-2-yl)-1<i>H</i>-imidazol-5-yl]-1,3-benzothiazole (TASP0382088): A Potent and Selective Transforming Growth Factor-β Type I Receptor Inhibitor as a Topical Drug for Alopecia 2013 · 6 citations
    21. Transforming growth factor-alpha immunoreactivity during induced hair follicle growth cycles in sheep and ferrets. 1996 · 6 citations
    22. Expression of Long Noncoding RNA, HOTAIR, and MicroRNA-205 and Their Relation to Transforming Growth Factor β1 in Patients with Alopecia Areata Skin Appendage Disorders · 2023 · 4 citations
    23. Growth Differentiation Factor 11 (GDF11)/Transforming Growth Factor - β (TGF - β)/Mesenchymal Stem Cells (MSCs) Balance: A Complicated Partnership in Skin Rejuvenation Journal of Embryology & Stem Cell Research · 2019 · 1 citations
    24. Perbandingan Kadar Transforming Growth Factor-Beta 1 pada Platelet Rich Plasma dengan Metode Pure dan Buffy Coat pada Populasi Individu Sehat Intisari Sains Medis · 2025
    25. 484 Transforming growth factor-β signaling-mediated wound healing is required hair follicle neogenesis Journal of Investigative Dermatology · 2024
    26. Serum Levels of Transforming Growth Factor Beta1 (TGF β1) in Patients with Alopecia Areata. Benha Medical Journal · 2020
    27. Effect of freeze-drying process of collagen-activated platelet-rich plasma on transforming growth factor-β1 level Majalah Kedokteran Gigi Indonesia · 2020
    28. Alopesi areata hastalarında serum interferon-gama, tümör nekrozis faktör-alfa, interlökin-13, interlökin-17 ve transforming growth faktör-beta düzeylerinin değerlendirilmesi 2016
    29. Expression of transforming growth factor-β_1 and tumor necrosis factor-α in mice with radiationinduced pulmonary injury 2010
    30. Effects of Epidermal Growth Factor and Transforming Growth Factor on Cultured Hair Follicle Cells from Human Scalp Skin research · 1994