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The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.

The vitamin D receptor helps maintain hair and bone health even without binding vitamin D.

Deleting MED1 in skin cells causes hair loss and skin changes.

The vitamin D receptor can work without its usual activating molecule.

Metabolic signals and cell shape influence how cells develop and change.

The study found that androgen receptors in skin cells mainly affect the focal adhesion pathway and control the caveolin-1 gene, with implications for new treatments for related diseases.

RNA editing significantly affects hair growth and follicle cycling in the Tianzhu white yak.

SIRT7 protein is crucial for starting hair growth in mice.

Bolandiol, a synthetic steroid, builds muscle and bone without greatly affecting sex glands, and works differently from other hormones.

PBX1 helps reduce aging and cell death in hair follicle stem cells by decreasing DNA damage, not by improving DNA repair.

New treatments targeting androgen receptors show promise for drug-resistant prostate cancer.

Vitamin D is important for bones, hair, blood pressure, and breast development.

Two rare genetic diseases cause severe rickets in children due to defects in vitamin D metabolism.

Mice without the vitamin D receptor are more prone to UV-induced skin tumors.

Involucrin gene expression is controlled by specific proteins and signaling pathways.

Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.

Hairless protein can block vitamin D activation in skin cells.

Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.

Bezafibrate treatment improved skin and spleen health in aging mice but didn't extend lifespan.

The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.

Vitamin D receptor is important for regulating hair growth and wound healing in mice.

Salvia plebeia extract can stimulate hair growth.

Testosterone can help premenopausal and postmenopausal women with low sexual desire, but its long-term safety is unclear and it's not widely approved for this use.

The vitamin D receptor helps regulate skin and hair health independently of its usual vitamin D ligand.

Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.

Mutations in the NR3C1 gene cause a rare condition that affects hormone signaling and can lead to various symptoms, with dexamethasone as a treatment option.

As skin cells mature, vitamin D receptor levels decrease while retinoid X receptor α levels increase.

The vitamin D receptor can act without its usual activating molecule, affecting hair growth and skin cancer, but its full range of actions is not well understood.

PPARγ is essential for maintaining healthy skin, controlling inflammation, and ensuring proper skin barrier function.