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The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.

MIM is crucial for hair follicle formation and regeneration by controlling cilia formation and hedgehog signaling through its interaction with Cortactin and Src.

Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

Animals that change color with the seasons mainly do so in response to daylight changes, but climate change is causing camouflage problems that may require evolutionary changes.

Hair, teeth, and mammary glands develop similarly at first but use different genes later.

Manipulating the catagen and telogen phases of hair growth could lead to treatments for hair disorders.

UV radiation can help sterilize wounds and promote healing but requires careful use to avoid damaging cells.

A specific drug can help treat Lichen Planopilaris, a condition causing permanent hair loss.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

Newborn mouse skin cells can grow hair and this process can be recreated in adult cells to potentially help with hair loss.

Skin fat helps with body temperature control and has other active roles in health.

All-trans retinoic acid causes hair loss by increasing TGF-β2 in hair follicle cells.

The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.

Minoxidil helps hair growth by activating the β-catenin pathway.

Six new genetic regions linked to early hair loss also connect to Parkinson's disease and prostate cancer, possibly leading to new treatments.

Activating the Wnt/β-catenin pathway could lead to new hair loss treatments.

The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.

Mouse skin can produce and process serotonin, with variations depending on hair cycle, body location, and mouse strain.

Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.

Drosha and Dicer are essential for hair follicle health and preventing DNA damage in skin cells.

Skin has specialized touch receptors that can tell different sensations apart.

The tumor suppressor gene FLCN affects mitochondrial function and energy use in cells.

Muscles and nerves that cause goosebumps also help control hair growth.

Wnt10b overexpression can regenerate hair follicles, possibly helping treat hair loss and alopecia.

Dermal Papilla cells are a promising tool for evaluating hair growth treatments.

Targeting the skin's endocannabinoid system could help treat skin disorders.

The circadian clock influences the behavior and regeneration of stem cells in the body.