9 citations
,
May 2014 in “BMC medical genetics” In this case report, the authors suggest that a novel enhancer element's translocation near the TRPS1 gene may contribute to the TRPS phenotype, expanding understanding of the syndrome's genetic basis.
32 citations
,
January 2000 in “International Journal of Cancer” In this study, the researchers observed significant down-regulation of Transglutaminase-3 expression in esophageal cancer tissues compared to normal tissues, suggesting its alteration is a common event in esophageal cancer development.
3 citations
,
May 2024 in “Cureus” This review revisits hair-thread tourniquet syndrome, highlighting the importance of prompt diagnosis and treatment by removing the constricting hair or similar substance to prevent damage to affected body parts, aiming to raise healthcare professionals' awareness for better prevention and management.
14 citations
,
January 2011 in “The International Journal of Developmental Biology” This study showed that coexpression of TG2 and Gbx1 in the epidermis is necessary for esophagus-like mucosal transdifferentiation, with TGF-beta2 in the dermis essential for the process through epithelial-mesenchymal interaction.
April 2024 in “American Journal of Case Reports” This case study reported that endotracheal hair growth following tracheal restructuring with an autograft was associated with cigarette smoking, and was ultimately stopped by argon plasma laser-coagulation and smoking cessation.
28 citations
,
August 2005 in “Journal of Investigative Dermatology” TG5 helps maintain hair follicle health, while TG3 aids in hair shaft development.
288 citations
,
January 2001 in “Journal of Biological Chemistry” In this study, the disruption of Gh/tissue transglutaminase in mice did not affect viability but reduced thymocyte viability and fibroblast adhesion, suggesting its role in cell stabilization and extracellular matrix interactions.
October 2012 in “The American Journal of Gastroenterology” This case report details a 21-year-old female diagnosed with a massive gastric trichobezoar due to trichophagia, successfully treated with single incision laparoscopic surgery and slated for psychiatric follow-up to prevent recurrence.
8 citations
,
January 2023 in “International journal of molecular sciences” This study reveals that transglutaminase activity is widespread in integumentary structures of mammals and birds, suggesting it plays a significant role in the cornification of hard skin appendages like nails and feathers.
April 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that gap junctional communication influences feather patterning by modulating Turing-type activator-inhibitor systems in chicken skin, suggesting its role in propagating inhibitory signals crucial for pattern formation.
14 citations
,
May 1979 in “International Journal of Dermatology” In this study, trichostasis spinulosa was observed in 51 patients with lesions on the nose, where some follicles contained up to 86 hairs each, possibly influenced by endocrine factors and actinic rays.
2 citations
,
January 2014 in “Dermatology Online Journal” This article reviews hair-thread tourniquet syndrome, discussing its demographics, causes, and current treatment methods, but presents no new clinical findings.
46 citations
,
November 2007 in “Gene Expression Patterns” This study observed that Trps1 gene expression in mice is precisely regulated in skin development, particularly during hair follicle morphogenesis, with distinct localization patterns in different cell types.
7 citations
,
January 2016 in “Laboratory Investigation” TR3 is mainly found in hair follicle stem cells and may be involved in hair loss.
29 citations
,
January 2021 in “Translational Psychiatry” This study found that certain gene sets, including those involved in ligand-gated ion channel signaling and cell adhesion, are associated with Tourette syndrome, suggesting a potential neurobiological basis for the disorder.
1 citations
,
January 2020 in “Skin appendage disorders” This case study documents the co-existence of trichorhinophalangeal syndrome and loose anagen syndrome in a patient, highlighting a previously unreported association between the two conditions.
2 citations
,
November 2017 in “Case Reports” This case report describes an instance of hair thread tourniquet syndrome in an infant, successfully treated through surgical release of the constricting hair.
35 citations
,
January 2000 in “Journal of comparative neurology” This study re-examined the structure of lanceolate endings in rat vibrissae, suggesting that their apical cones may function as a transducer site for detecting hair movements.
March 2024 in “IP Indian journal of clinical and experimental dermatology” This case report highlighted the rarity and diagnostic challenges of a giant solitary trichoepithelioma occurring on the neck, noting that while typically benign, these tumors can rarely transform malignantly into basal cell carcinoma.
61 citations
,
February 1982 in “Cell and Tissue Research”
6 citations
,
January 2018 in “Acta dermatovenerologica Alpina, Pannonica et Adriatica (Tiskana izd.)” This case report describes the successful surgical removal of a trichobezoar in an 8-year-old girl, which extended from her stomach into the duodenum.
118 citations
,
June 1993 in “Journal of Biological Chemistry” This study found that mouse and human protransglutaminase 3 enzymes require calcium-regulated activation for their role in later stages of cell envelope formation in the epidermis and hair follicle.
1 citations
,
April 2020 in “medRxiv (Cold Spring Harbor Laboratory)” This study identified gene sets associated with Tourette Syndrome, implicating Ligand-gated Ion Channel Signaling, Lymphocytic, and Cell Adhesion and Trans-synaptic Signaling processes in the disorder's neurobiology.
June 2023 in “British journal of dermatology/British journal of dermatology, Supplement” In this study, two cases of cutis verticis gyrata were associated with chronic traction alopecia due to tight hairstyles, highlighting the need to consider hairstyling history in diagnosis and management.
December 2025 in “TURKDERM” This article discusses Trikostazis spinuloza (TS), a dermatological condition often misdiagnosed, and reviews its demographic, clinical, and dermoscopic features, but reports no new clinical results.
1 citations
,
April 2020 in “Asian Journal of Medicine and Biomedicine” This article reports a case of hair tourniquet syndrome in a child's toe, successfully treated surgically, and emphasizes the need for healthcare providers to be aware for early detection and treatment.
22 citations
,
August 2020 in “Cells” This review discusses the role of TGM3 in skin and hair follicle biology, human tumor pathology, and genetic abnormalities, and reports no novel results; the authors highlight its potential as a cancer diagnostic biomarker.
May 2022 in “European medical journal” This case report describes a rare instance of a patient with trichotillomania also developing a gastric trichobezoar, leading to Rapunzel syndrome.
August 2022 in “Archives of pediatric surgery” This article reviews cultural differences in the incidence of hair-thread tourniquet syndrome and finds it may be less prevalent in Iranian children compared to Europe, possibly due to social and cultural factors.
1 citations
,
January 2001 in “PubMed” This study proposes that the terminal tuft structure in sensory nerve endings, involving Schwann cell processes and axon fingers, potentially plays a role in mechano-electric transduction in rats.