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Hormone therapy increases the risk of heart-related issues in transgender women and may affect heart health in transgender men.

Most women with PCOS have insulin resistance, especially those with phenotype B.

Older men with lower levels of available testosterone are more likely to be frail.

Sex hormone treatments can increase muscle mass in older adults but have inconsistent effects on muscle function and may carry cardiovascular risks.

Testosterone therapy can improve sexual function in women but long-term safety is unclear.

New treatments for male hypogonadism are effective and should be personalized.

Nanocarriers could improve how drugs are delivered through the skin but require more research to overcome challenges and ensure safety.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Future hormone therapy trials should match the diverse needs and priorities of the gender-diverse community.

Sarcoptes scabiei infection causes significant health and behavior changes in wombats.

Anorexia and bulimia lead to serious health problems and increased risk of death, requiring aggressive treatment.

Finasteride for hair loss may cause persistent sexual symptoms, depression, anxiety, and lower quality of life.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

The Rotterdam Study aims to understand various diseases in older adults.

Sons of mothers with polycystic ovary syndrome (PCOS) have a higher risk of obesity and insulin resistance, possibly due to certain genes and factors passed down from their mothers.

Deleting MPZL3 increases skin oil production and reduces body fat.

Micronutrient supplements significantly improved PCOS symptoms in women.

Women with PCOS have overall higher body fat, not abnormal fat placement, and more insulin resistance.

Daughters of women with PCOS generally experience normal puberty but may have more body hair and different body fat distribution.

Increased HSD11B1 enzyme expression is linked to higher body fat and insulin resistance.

Human body's immune cells are more common in the layer of fat just beneath the skin than in deeper fat layers.

Fat tissue stem cells show promise for repairing different body tissues and are being tested in clinical trials.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

Tamoxifen can cause total hair loss but its benefits outweigh this side effect.

Changes in testosterone and estrogen receptor genes can affect how men age, influencing body fat, hair patterns, and possibly leading to skin disorders.

Higher testosterone levels can increase the risk of certain diseases like type 2 diabetes in women and prostate cancer in men, but can also protect against autoimmune diseases and hair loss. It also affects body fat and bone density.

Lower lipin 1β in belly fat is linked to insulin resistance in people with polycystic ovary syndrome.