Association of Insulin Resistance with Polycystic Ovary Syndrome Phenotypes and Patients’ Characteristics: A Cross-Sectional Study in Iran

November 2023 in “ Reproductive biology and endocrinology ”

Leili Rahmatnezhad, Lida Moghaddam-Banaem, Tahereh Behroozi-Lak, Atena Shiva, Javad Rasouli

insulin resistance polycystic ovary syndrome PCOS phenotype B hemoglobin levels IR

TLDR Most women with PCOS have insulin resistance, especially those with phenotype B.

This cross-sectional study in Iran assessed insulin resistance (IR) among 160 women with polycystic ovary syndrome (PCOS) and found that 74.4% had IR, with phenotype B showing the highest rate (91.9%). Significant associations were observed between IR and PCOS phenotypes, economic status, and hemoglobin levels. The study emphasizes the importance of identifying PCOS phenotypes for better management of the condition and its complications, though further research is needed.

View this study on rbej.biomedcentral.com →

Discuss this study in the Community →

Research cited in this study

7 / 7 results

research Polycystic Ovary Syndrome: Pathogenesis, Treatment, and Secondary Associated Diseases

4 citations, September 2018 in “Journal of Drug Delivery and Therapeutics”

PCOS is a common hormonal disorder in women linked to several health risks and can be managed through various treatments.

research Genetic, Hormonal, and Metabolic Aspects of PCOS: An Update

258 citations, July 2016 in “Reproductive Biology and Endocrinology”

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

research Metabolic Syndrome and Metabolic Risk Profile According to Polycystic Ovary Syndrome Phenotype

32 citations, April 2016 in “Journal of Obstetrics and Gynaecology Research”

Women with severe types of PCOS are more likely to have metabolic syndrome, and belly fat is a key predictor of this risk.

research Afamin Serum Concentrations Are Associated With Insulin Resistance and Metabolic Syndrome in Polycystic Ovary Syndrome

33 citations, September 2014 in “Reproductive Biology and Endocrinology”

High afamin levels are linked to metabolic syndrome and may predict its development in women with insulin resistance.

Consensus on Women's Health Aspects of Polycystic Ovary Syndrome: The Amsterdam ESHRE/ASRM-Sponsored 3rd PCOS Consensus Workshop Group

research Consensus on Women's Health Aspects of Polycystic Ovary Syndrome: The Amsterdam ESHRE/ASRM-Sponsored 3rd PCOS Consensus Workshop Group

1514 citations, December 2011 in “Fertility and sterility”

Experts agree that PCOS affects women's health in complex ways, but more research is needed to understand and treat it effectively.

research The Prevalence of Idiopathic Hirsutism and Polycystic Ovary Syndrome in the Tehran Lipid and Glucose Study

51 citations, November 2011 in “Reproductive Biology and Endocrinology”

About 13% of women had idiopathic hirsutism and 8.5% had polycystic ovary syndrome in a group of Iranian women.

research Revised 2003 Consensus on Diagnostic Criteria and Long-Term Health Risks Related to Polycystic Ovary Syndrome (PCOS)

4025 citations, December 2003 in “Human Reproduction”

The 2003 consensus updated PCOS diagnosis criteria and linked PCOS to higher risks of diabetes and heart problems, recommending lifestyle changes to lower these risks.

Related Community Posts Join

6 / 144 results

community Female, 30, PCOS diagnosis, MPB Norwood 2. Endo refuses to give anything other than Spironolactone. Feel like I’m at my wit’s end here.

in Female 53 upvotes 1 year ago

A 30-year-old female with PCOS and male pattern baldness is frustrated with her endocrinologist's recommendation of only Spironolactone and minoxidil, feeling that dutasteride, finasteride, and progesterone would be more effective. Other users suggest various online sources for treatments, warn against self-medicating due to potential risks, and recommend seeking a specialized endocrinologist or considering additional treatments like Inositol, Berberine, and dermaneedling.

community Why balding gets worse in every generation?

in Chat 81 upvotes 6 months ago

Balding seems to worsen with each generation, possibly due to stress, diet, and environmental factors. The user started treatments like Minoxidil and finasteride.

community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 4 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community [25, F] [RANT] Shedding since March 2020. This just isn’t fair.

in Female 42 upvotes 3 years ago

User "missbloombastic" has been experiencing hair loss since 2016 and tried min, fin, multivitamins, and spiro with mixed results. Another user shares their struggle with hair loss and its impact on self-esteem, while a third user suggests checking blood tests and confirming the cause of hair loss.

community What treatment helps diffuse hair thinning from insulin resistance?

in Treatment 1 upvotes 1 year ago

The individual is experiencing hair loss due to insulin resistance (IR) and is seeking advice. They are currently using a keto diet, supplements, exercise, and plan to add metformin to their regimen.

community ‘Long term use of fin/dut may be associated with health risks including fatty liver disease, insulin resistance, type 2 diabetes, dry eye disease and potential kidney disease.’

in Research/Science 22 upvotes 5 months ago

Long-term use of finasteride and dutasteride may be linked to health risks like fatty liver disease, insulin resistance, type 2 diabetes, dry eye disease, and potential kidney disease. Some users believe the risks are low and the medications are generally safe.

Related Research

3 / 3 results

research Current Aspects of Polycystic Ovary Syndrome: A Literature Review

15 citations, December 2016 in “Revista Da Associacao Medica Brasileira”

Polycystic ovary syndrome is a common hormonal disorder in women, linked to increased risk of metabolic and heart diseases, and needs more research for better understanding and treatment.

research Caring for Women with Polycystic Ovary Syndrome

1 citations, May 2016 in “The Nurse Practitioner”

Treating PCOS is complex, involving medication like metformin and lifestyle changes, and requires attention to mental health due to high depression and anxiety rates.

research Screening for Diabetes in Women with Polycystic Ovary Syndrome

3 citations, March 2007 in “Canadian Medical Association Journal”

Women with PCOS should have an oral glucose tolerance test for effective diabetes screening.