February 2025 in “Clinical & Experimental Dermatology and Therapies” In this randomized trial, oral supplementation with Serenoa repens, pumpkin seed extracts, and cysteine significantly improved the clinical effectiveness of topical 5% minoxidil lotion for treating androgenic alopecia in men and women compared to minoxidil alone, with both treatments being well tolerated.
18 citations
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May 2015 in “Australasian Journal of Dermatology” This study found that topical application of Serenoa repens extract increased hair count in men with androgenetic alopecia, suggesting it could be an alternative for those unable to use standard medications.
September 2014 in “Hair transplant forum international” This article discusses the role of transplantation in hair restoration but reports no new clinical findings.
December 2024 in “Skin Appendage Disorders” Researchers reviewed 13 clinical trials on non-prescription monotherapies like procyanidin and cetirizine for androgenetic alopecia, finding potential improvements in hair density and diameter, but emphasized the need for more robust trials to confirm efficacy and safety.
This review found inconsistent evidence on the effectiveness of oral finasteride for hair loss reversal in men with androgenetic alopecia, with one study showing significant results and others not.
September 2017 in “Zenodo (CERN European Organization for Nuclear Research)” This study suggests that a topical hydroalcoholic extract of liquorice root significantly reduced sebaceous gland size in Syrian hamsters, indicating potential for use in anti-acne therapy.
1 citations
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March 2014 in “Senses and Sciences” This article describes a clinical case of a 67-year-old patient with telogen effluvium treated with a supplement containing amino acids, vitamin E, iron, and Serenoa repens, but reports no new clinical findings.
January 2015 in “Hair therapy & transplantation” This review discusses natural and botanical products examined for treating alopecia and reports no clinical results; the authors note growing research interest in these treatments.
30 citations
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September 2011 in “International Wound Journal” This study found that platelet-rich plasma therapy significantly improved wound area and depth reduction in chronic wounds compared to pre-treatment, suggesting registry data can effectively complement traditional clinical trials.
1 citations
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April 2025 in “Experimental Dermatology” This systematic review assessed the off-label use of topical Ruxolitinib cream for various skin conditions and found it effective for lichenoid and granulomatous dermatoses, though results for alopecia areata were inconsistent. The authors indicate that further research is warranted to confirm these findings.
April 2024 in “Journal of endocrinological investigation” This study found that topical minoxidil significantly enhanced facial hair growth in transgender individuals assigned female at birth undergoing gender affirming hormone therapy, with improvements most notable after six months of use.
1 citations
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July 2025 in “Journal of Cosmetic Dermatology” This case report suggests that exosome therapy may offer a promising alternative treatment for lichen planopilaris, showing potential benefits in hair regrowth, reduced inflammation, and improved scalp condition, but further studies are needed to confirm long-term efficacy and safety.
June 2023 in “Journal of cosmetic dermatology” This case report highlights a patient who developed cutaneous sarcoidal lesions at the site of platelet-rich plasma injections after COVID-19 infection and vaccination, suggesting possible immune system involvement.
19 citations
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September 2014 in “British Journal of Dermatology” This study found that topical minoxidil 5% foam was effective in promoting hair growth in both the frontal and vertex scalp for men with androgenetic alopecia.
1 citations
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January 2005 in “Side effects of drugs annual” This chapter reviews various dermatological drugs and treatments, highlighting adverse effects, with no new clinical findings reported.
December 2014 in “Turk Dermatoloji Dergisi” This study found that a hair lotion containing saw palmetto and 10% trichogen veg complex increased total hair count in male patients with androgenetic alopecia over four months, though observer assessments varied.
3 citations
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August 2021 in “Uro” This review concludes that global literature supports the lipidosterolic extract of Serenoa repens as efficacious and safe for treating lower urinary tract symptoms, with some studies showing equivalence to common pharmacologic agents.
51 citations
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October 2012 in “International Journal of Immunopathology and Pharmacology” In this study, 68% of patients treated with finasteride showed improved hair growth in male androgenetic alopecia, compared to 38% with Serenoa repens, indicating finasteride's superior efficacy.
21 citations
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June 2017 in “Journal of Dermatological Treatment” This study found that topical cetirizine 1% significantly improved hair density and diameter in patients with androgenetic alopecia, with patients tolerating the treatment well.
6 citations
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October 2012 in “Pediatrics” This case report describes an 11-year-old girl who experienced hot flashes and menarche after taking a Serenoa repens supplement for telogen effluvium, suggesting a possible but uncertain link between the supplement and hormonal changes.
3 citations
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January 2017 in “Journal of cosmetology & trichology” In this clinical trial, supplementation with Lambdapil® Anti Hair Loss capsules for 6 months significantly improved hair resistance and volume in women and increased the anagen/telogen hair ratio in men, indicating enhanced hair growth compared to the placebo group.
2 citations
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April 2016 in “Más dermatología” This study found that the dietary supplement RJ-SP4AGA significantly improved hair growth and reduced hair loss in post-menopausal women with androgenetic alopecia over 16 weeks.
2 citations
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December 2003 This article discusses Serenoa repens (Saw palmetto) for preventing and treating androgenic alopecia, highlighting its phytosterols' role and lack of side effects but reports no new clinical results.
October 2025 in “Scientific Reports” This study found that the extracts of Serenoa repens, when evaluated through chemical, biological, and in silico methods, demonstrated anti-inflammatory, pro-apoptotic, and anti-androgenic activities against prostate cancer cell lines, suggesting potential therapeutic benefits and directing future pharmaceutical development.
November 2022 in “Medicina Estética Revista Científica de la Sociedad Española de Medicina Estética (SEME)” This study aimed to evaluate the effectiveness of a hair conditioner containing Serenoa serrulata extract and tocoferol applied 3-4 times per week for 90 days against androgenic alopecia.
January 2004 in “Side effects of drugs annual” Certain skin drugs and topical agents, including some natural extracts and fragrances, can cause allergic reactions. Some hair dyes and extensions, as well as minoxidil, a hair growth treatment, can also cause allergies. Botulinum toxin A can effectively reduce sweat but may have temporary side effects.
17 citations
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November 2002 in “Australasian Journal of Dermatology” This case report describes a 24-year-old woman with androgenetic alopecia who developed sensitivity to topical minoxidil and later to saw palmetto after using a minoxidil and retinoic acid preparation.
4 citations
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February 2021 in “Journal of Cosmetic Dermatology” This study found that pumpkin seed oil significantly improved hair parameters in females with pattern hair loss, demonstrating potential as a treatment comparable to minoxidil 5% foam.
3 citations
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July 2023 in “Cells” This study found that topical application of recombinant human MG53 protein mitigated nitrogen mustard-induced skin injuries in mice by preserving epidermal integrity and hair follicle structure.
January 2003 in “American Journal of Clinical Dermatology” In 2002, various skin reactions were reported due to different drugs, including allergies, hair loss, skin lesions, and other skin conditions.