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Melanocytes produce melanin; their defects cause vitiligo and hair graying, with treatments available for vitiligo.

Pregnancy can cause skin changes and conditions that need correct diagnosis and treatment for the health of the mother and baby.

Inhibiting PLA2 enzymes may help treat inflammatory skin diseases like psoriasis and dermatitis.

Cornu cervi pantotrichum pharmacopuncture solution helps mice grow hair by increasing hair follicle cell growth and a growth factor important for hair development.

Skin structure complexity and variability are crucial for assessing skin toxicity in safety tests.

A man developed skin issues from cancer medication, which improved with specific treatments.

Cyclosporin A and FK506 can start new hair growth in mice, but ascomycin and rapamycin cannot.

Afatinib often causes skin problems that need proactive management.

Drugmakers are optimistic about targeting the Wnt pathway for new treatments despite past challenges.

Hirsutism treatments can slow new hair growth, but existing hair needs removal, and eflornithine helps reduce hair growth.

Bicalutamide, a drug with a good safety profile, is a promising new treatment for female pattern hair loss.

Finasteride and minoxidil are effective for hair loss, but continued research is needed for better treatments.

Exosomes are important for skin treatments and hair growth but need more research for safe and effective use.

Topical therapies show promise for hair loss and acne treatment with minimal side effects.

Minoxidil promotes hair growth but stops working when discontinued.

Nanotechnology improves minoxidil treatment for hair loss.

Lecithin-based microparticles can deliver minoxidil for hair growth effectively with less skin irritation.

Bimatoprost 0.03% solution effectively promotes eyebrow growth.

Topical treatments can deliver active molecules to skin stem cells, potentially helping treat skin and hair disorders, including skin cancers and hair loss.

Topical patidegib gel effectively treats basal cell carcinoma in Gorlin syndrome patients without causing the side effects seen with oral treatments.

Lecithin organogels could be good for applying drugs to the skin because they are stable, safe, and can improve drug absorption.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Niosomes are promising for skin drug delivery, offering benefits like improved drug penetration and stability.

Topical JAK inhibitors may help treat some skin conditions but need more research.

RTA 408 cream protects mice from radiation skin damage.

Minoxidil helps hair regrowth in alopecia areata safely.

Topical latanoprost and bimatoprost eye solutions don't help eyelash growth in people with alopecia areata.

Using minoxidil on the scalp can help grow hair for people with hereditary baldness.

Using topical minoxidil for baldness can cause heart problems, especially in those with heart disease.

Topical finasteride and flutamide reduce gland size and enzyme activity, with flutamide being more potent, potentially treating acne, seborrhea, hirsutism, and androgenic alopecia.