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    Glossary Tissue Plasminogen Activator

    protein that dissolves blood clots by activating plasminogen

    Tissue Plasminogen Activator (TPA) is a protein involved in the breakdown of blood clots. It converts plasminogen, an inactive protein in the blood, into plasmin, an enzyme that dissolves clots. TPA is often used in medical treatments to quickly dissolve clots in patients experiencing heart attacks or strokes.

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    1. Anaphylactic Shock Due to Intravenous Amiodarone; Delusional Parasitosis Associated with Donepezil; Connubial Androgenetic Alopecia; Ciprofloxacin-Induced Torsade de Pointes; Postvaccination Miller Fisher Syndrome; Life-Threatening Anaphylactoid Shock Caused by Recombinant Tissue Plasminogen Activator; Thiazide-Induced Hyponatremia Hospital Pharmacy · 2012
    2. Proteomics Characterization of Primary Human Oral Epithelial Cells Using a Novel Culture Technique for Use in Tissue Regeneration MOJ proteomics & bioinformatics · 2015
    3. 644 Tumor cell adhesion as a risk factor for SLN metastasis and predictor of disease recurrence in primary cutaneous melanoma Journal of Investigative Dermatology · 2016
    4. Role of plasminogen activator inhibitor type 1 (PAI-1) in PCOS patient International journal of reproduction, contraception, obstetrics and gynecology · 2017 · 3 citations
    5. Localization of Plasminogen Activator Inhibitor Type 2 (PAI-2) in Hair and Nail: Implications for Terminal Differentiation 1998 · 42 citations
    6. Oral contraceptive pill (OCP) treatment alters the gene expression of intercellular adhesion molecule-1 (ICAM-1), tumor necrosis factor-α (TNF-α), monocyte chemoattractant protein-1 (MCP-1) and plasminogen activator inhibitor-1 (PAI-1) in polycystic ovary syndrome (PCOS) women compared to drug-naive PCOS women BMC women's health · 2023 · 2 citations
    7. Transient Ca2+ entry by plasmalogen-mediated activation of receptor potential cation channel promotes AMPK activity Frontiers in molecular biosciences · 2022 · 3 citations
    8. Urokinase is a Positive Regulator of Epidermal Proliferation In Vivo Journal of Investigative Dermatology · 1999 · 28 citations
    9. Current Concepts and Translational Uses of Platelet Rich Plasma Biotechnology InTech eBooks · 2015 · 12 citations
    10. Defining stem cell dynamics and migration during wound healing in mouse skin epidermis Nature Communications · 2017 · 363 citations
    11. Protease-Activated Receptor-1 (Thrombin Receptor) Is Expressed in Mesenchymal Portions of Human Hair Follicle Journal of Investigative Dermatology · 2003 · 7 citations
    12. Transforming growth factor-β in stem cells and tissue homeostasis Bone Research · 2018 · 245 citations
    13. Wound healing in development Birth Defects Research · 2012 · 29 citations
    14. Transcriptomic Analysis of Skin Tissue Reveals Molecular Mechanisms of Thermal Adaptation in Cold-Exposed Lambs Animals · 2025
    15. The Multifaceted Functions of TRPV4 and Calcium Oscillations in Tissue Repair International journal of molecular sciences · 2024 · 1 citations
    16. The role of nuclear hormone receptors in cutaneous wound repair Cell Biochemistry and Function · 2014 · 68 citations
    17. Extracellular Matrix Degradation Products and Low-Oxygen Conditions Enhance the Regenerative Potential of Perivascular Stem Cells Tissue Engineering Part A · 2010 · 91 citations
    18. Fibroblast Growth Factor-7 and Hair Biology: Bridging Basic Science and Therapeutic Applications Current Issues in Molecular Biology · 2026
    19. γδ17 T cell-stromal networks modulate matrix composition and vascularity in foreign body response 2026 · 1 citations
    20. Fabrication and characterization of epithelial scaffolds for hair follicle regeneration Tissue Engineering and Regenerative Medicine · 2012 · 4 citations
    21. The PDGF/PDGFR pathway as a drug target Molecular Aspects of Medicine · 2017 · 182 citations
    22. Ku80 as a Novel Receptor for Thymosin β4 That Mediates Its Intracellular Activity Different from G-actin Sequestering Journal of Biological Chemistry · 2007 · 37 citations
    23. Autologous Platelet and Extracellular Vesicle-Rich Plasma as Therapeutic Fluid: A Review International Journal of Molecular Sciences · 2023 · 3 citations
    24. Cellular senescence in tissue repair: every cloud has a silver lining The International Journal of Developmental Biology · 2018 · 33 citations
    25. Interrelation of immunity and tissue repair or regeneration Seminars in Cell & Developmental Biology · 2009 · 252 citations
    26. Surface modification and endothelialization of biomaterials as potential scaffolds for vascular tissue engineering applications Chemical Society Reviews · 2015 · 421 citations
    27. Tissue Engineering and Regenerative Medicine: Achievements, Future, and Sustainability in Asia Frontiers in Bioengineering and Biotechnology · 2020 · 119 citations
    28. Electrospun Nanofibers for Improved Angiogenesis: Promises for Tissue Engineering Applications Nanomaterials · 2020 · 70 citations
    29. Platelet-Therapeutics to Improve Tissue Regeneration and Wound Healing—Physiological Background and Methods of Preparation Biomedicines · 2021 · 14 citations
    30. Decreased lipin 1β expression in visceral adipose tissue is associated with insulin resistance in polycystic ovary syndrome European journal of endocrinology · 2008 · 20 citations