118 citations
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August 2010 in “Developmental Cell” MIM is crucial for hair follicle formation and regeneration by controlling cilia formation and hedgehog signaling through its interaction with Cortactin and Src.
40 citations
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April 2014 in “Genes & Development” Hormones during pregnancy and lactation keep skin stem cells inactive, preventing hair growth.
44 citations
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April 2017 in “Genes & development” Scientists found cells in hair that are key for growth and color.
179 citations
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July 2016 in “Nature Reviews Molecular Cell Biology” Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.
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March 2013 in “ISRN Stem Cells (Online)” Skin stem cells were turned into heart cells using a chemical, suggesting a new way to treat heart attacks.
130 citations
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September 2018 in “Cell Reports” Macrophages help heal nerves by aiding the maturation of Schwann cells and are important for nerve repair.
72 citations
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December 2012 in “Journal of Investigative Dermatology” Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.
33 citations
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February 1999 in “The journal of investigative dermatology/Journal of investigative dermatology” IGF-1 increases whisker growth in transgenic mice.
3 citations
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October 2022 in “PloS one” Scientists have developed a method to keep chicken feather follicles alive and structurally intact in a lab for up to a week.
January 2024 in “Aging” New insights into cell communication in psoriasis suggest innovative drug treatments.
November 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Disrupted cholesterol production impairs hair follicle stem cells, leading to hair loss.
77 citations
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August 2009 in “British Journal of Dermatology” Aromatase gene variation may increase female hair loss risk.
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January 2018 in “Dermatologic Clinics” New techniques improve hair restoration success.
10 citations
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October 2008 in “Andrologia” Finasteride changes antioxidant enzyme expression, possibly affecting sperm protection in rats.
December 2023 in “Aggregate” Scientists are using clumps of special stem cells to improve organ repair.
258 citations
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July 2005 in “Journal of lipid research” DGAT1 enzyme helps make diacylglycerols, waxes, and retinyl esters.
48 citations
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May 2019 in “Genome Biology” Researchers found that certain RNA circles in the brain are linked to disease risk, but their exact role in disease is still unknown.
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July 2019 in “Journal of Cellular Biochemistry” Wnt7a protein is crucial for development and tissue maintenance and plays varying roles in diseases and potential treatments.
September 2023 in “Membranes” 3D-printed membranes with smart sensors can greatly improve tissue healing and have many medical applications.
40 citations
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March 2019 in “Nature Communications” CRAC channels are crucial for the development and function of specialized immune cells, preventing severe inflammation and autoimmune diseases.
1 citations
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December 2022 in “Frontiers in Immunology” Tissue environment greatly affects the unique epigenetic makeup of regulatory T cells, which could impact autoimmune disease treatment.
33 citations
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January 2018 in “The International Journal of Developmental Biology” Cell aging can be both good and bad for tissue repair.
41 citations
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June 2013 in “PLOS ONE” Engineered skin substitutes can grow hair but have limitations like missing sebaceous glands and hair not breaking through the skin naturally.
7 citations
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February 2018 in “InTech eBooks” Biomaterials combined with stem cells show promise for improving tissue repair and medical treatments.
12 citations
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December 2020 in “Archives animal breeding/Archiv für Tierzucht” EDA and EDAR are important for hair follicle development in cashmere goats and affect other related genes.
2 citations
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January 2023 in “Applied Science and Convergence Technology” 3D bioprinting is useful for making tissues, testing drugs, and delivering drugs, but needs better materials, resolution, and scalability.
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October 2020 in “Frontiers in cell and developmental biology” WWOX deficiency in mice causes skin and fat tissue problems due to disrupted cell survival signals.
January 2018 in “Stem cells in clinical applications” Exosomes show promise for tissue repair and regeneration with advantages over traditional cell therapies.
658 citations
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June 2003 in “Endocrine reviews” Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.
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January 2019 in “Biochimica et Biophysica Acta (BBA) - Molecular Cell Research” Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.