Search
for
Sort by
Research
450-480 / 1000+ results
research The ZIP7 Gene (Slc39a7) Encodes a Zinc Transporter Involved in Zinc Homeostasis of the Golgi Apparatus
This study shows that ZIP7 is a functional zinc transporter in mammalian cells, facilitating the movement of zinc from the Golgi apparatus to the cytoplasm.
research Preventable effect of L-threonate, an ascorbate metabolite, on androgen-driven balding via repression of dihydrotestosteroneinduced dickkopf-1 expression in human hair dermal papilla cells
In this study, L-threonate was found to inhibit DHT-induced DKK-1 expression in cultured dermal papilla cells, suggesting it could help prevent androgen-driven balding.
research A single-cell transcriptomic atlas elucidates the hair cycle and apoptosis mechanisms in goat hair follicles
This study mapped a detailed genetic profile of goat hair follicle apoptosis, identifying key genes and regulatory factors involved in the hair cycle, offering new insights into programmed cell death.
research 43336 Low-dose oral minoxidil for alopecia: a single-center retrospective review
This review evaluates the clinical experience of using low-dose oral minoxidil for treating alopecia and highlights the ongoing concerns about its potential side effects without reporting new clinical results.
research IMMEDIATE HYPERSENSITIVITY TO PERMANENT HAIR COLOR: 7
In this study, tazarotene 0.1% gel showed greater efficacy than tretinoin 0.025% gel in reducing acne lesions and demonstrated similar efficacy to adapalene 0.1% gel when used less frequently.
research Severe and Fatal Phenobarbitone Eruptions
Phenobarbitone can cause severe and sometimes fatal skin reactions.
research Molecular Analysis of a Series of Israeli Families with Comèl-Netherton Syndrome
This study identified three SPINK5 mutations, including two novel ones, in Israeli patients with Comèl-Netherton syndrome, suggesting recurring mutations that should inform future diagnostic strategies in Israel.
research Teneligliptin-induced hair loss: A case report
This case report describes a 35-year-old male with Type 2 diabetes who experienced scalp hair loss after increasing his dose of Teneligliptin without supervision, which resolved after discontinuing the medication.
research Establishment and characterization of an immortalized human dermal papilla cell line
This study successfully established an immortalized human dermal papilla cell line that maintains characteristics of original cells without malignant transformation, potentially benefiting hair research.
research Identification of the sulfotransferase iso-enzyme primarily responsible for the bio-activation of topical minoxidil.
This abstract reports that topical minoxidil is currently the only FDA-approved treatment for pattern hair loss in both men and women.
research LncRNA RP11-818O24.3 promotes hair-follicle recovery via FGF2-PI3K/Akt signal pathway
research Film-trigger applicator (FTA) for improved skin penetration of microneedle using punching force of carboxymethyl cellulose film acting as a microneedle applicator
This study found that the film-trigger applicator system enhanced drug delivery efficiency and skin penetration of dissolving microneedles compared to traditional patch systems in both lab and animal models.
research The Type I Keratin 19 Possesses Distinct and Context-dependent Assembly Properties
This study found that keratin 19, unlike keratin 14, forms less stable filaments with keratin 5, suggesting distinct assembly properties and potential unique roles in skin basal cells.
research LncRNA H19 Overexpression Activates Wnt Signaling to Maintain the Hair Follicle Regeneration Potential of Dermal Papilla Cells
This study suggests that the long noncoding RNA H19 helps dermal papilla cells maintain their hair follicle-inducing ability by activating the Wnt signaling pathway, potentially offering a therapeutic target for androgenetic alopecia.
research Innovative Approaches to the Assessment of Alopecia Areata: Incorporating the SALT Index Through Transparent Devices
research Artificial Intelligence in Patient Education for Androgenetic Alopecia: A Comparative Study of ChatGPT, Gemini, and Deepseek R1
This study found that ChatGPT 4.0 and Gemini 1.5 Flash provided more accurate and user-friendly responses to androgenetic alopecia questions than Deepseek R1, suggesting they could be effective tools for patient education with physician guidance.
research TR3 is preferentially expressed by bulge epithelial stem cells in human hair follicles
TR3 is mainly found in hair follicle stem cells and may be involved in hair loss.
research Development and Optimization of Finasteride-Cinnamon Oil-Loaded Ethanol-Free Microemulsions for Transdermal Delivery
In this study, researchers developed and optimized ethanol-free microemulsion systems for transdermal finasteride delivery, finding that the predicted formulations closely matched their physical and chemical characteristics, potentially reducing adverse effects compared to oral administration.
research The Tissue-dependent Keratin 19 Gene Transcription Is Regulated by GKLF/KLF4 and Sp1
This study found that the K19 promoter is active in certain gastrointestinal cancer cells and its activity is influenced by the interaction between GKLF and Sp1 transcription factors.
research Additional file 9 of Time-course RNA-seq analysis reveals stage-specific and melatonin-triggered gene expression patterns during the hair follicle growth cycle in Capra hircus
Melatonin affects when and how goat hair follicle genes turn on and off during growth cycles.
research Apoptotic cells represent a dynamic stem cell niche governing proliferation and tissue regeneration
In this study, researchers found that deleting Caspase-9 in hair follicle stem cells delayed apoptosis, leading to accelerated wound repair and new hair follicle regeneration by maintaining apoptotic cells as signaling centers.
research Tumor necrosis factor-alpha inhibitor associated psoriasiform alopecia (drug-induced psoriasiform alopecia)
Some drugs for inflammation may cause psoriasis-like hair loss.
research Miz1 is required for hair follicle structure and hair morphogenesis
This study found that knocking out the transactivation domain of Miz1 in mouse keratinocytes disrupted hair follicle orientation, caused irregular pigmentation, and increased keratinocyte proliferation, indicating Miz1's role in hair follicle development and morphogenesis.
research Novel DualSoftDrug Strategy Enables Developmentof Topical Androgen Receptor Antagonists with Enhanced Efficacy andOptimized Safety for Androgenetic Alopecia
This study found that the optimized AR antagonist candidate 39, in a hair-growth mouse model, achieved similar efficacy to pyrilutamide with faster onset and favorable safety, suggesting a promising approach for developing topical treatments with low systemic toxicity for androgenetic alopecia.
research Toluene Diisocyanate (TDI) Disposition and Co-Localization of Immune Cells in Hair Follicles
This study found that skin exposure to toluene diisocyanate in mice creates immune-recognition reservoirs in the skin's stratum corneum and hair follicles, potentially leading to sensitization and allergic reactions.
research Efficacy of tip cryotherapy in the treatment of idiopathic guttate hypomelanosis (IGH): a randomized, controlled, evaluator-blinded study
This study evaluated the effects of tip cryotherapy on idiopathic guttate hypomelanosis lesions, finding that 82.3% of treated lesions showed significant improvement after four months compared to only 2% of control lesions, with minimal side effects.
research Identification of 736T>A mutation of lipase H in Japanese siblings with autosomal recessive woolly hair
This study identified a specific LIPH gene mutation (736T>A) as common in Japanese patients with autosomal recessive woolly hair/hypotrichosis, potentially indicating its role in the condition's manifestation within this population.
research Telogen Effluvium
Telogen effluvium is a condition that causes temporary hair loss.
research Telogen effluvium
Telogen effluvium is a condition that causes temporary hair loss.