Molecular Analysis of a Series of Israeli Families with Comèl-Netherton Syndrome

January 2014 in “ Dermatology ”

Shirli Israeli, Ofer Sarig, Ben Zion Garty, Margarita Indelman, Richard N. Bergman, Eli Sprecher, Ilan Goldberg

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Research cited in this study

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research Spink5-deficient mice mimic Netherton syndrome through degradation of desmoglein 1 by epidermal protease hyperactivity

372 citations , December 2004 in “Nature Genetics”

research Netherton's Syndrome: A Syndrome of Elevated IgE and Characteristic Skin and Hair Findings

124 citations , January 1995 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology”

Netherton's syndrome is linked to high IgE levels and unique skin and hair symptoms, and may improve with ammonium lactate lotion and allergy management.