August 2026 in “Cellular and Molecular Life Sciences” This study investigated the role of the glycoprotein Thy-1 in hypertrophic scar formation using a murine model, finding that Thy-1 knockdown reduced scar size and encouraged functional regeneration by influencing the p38MAPK signaling pathway under high-tension conditions.
This study observed that individuals with autoimmune thyroid disease in Georgia had significantly higher frequencies of certain symptoms and Anti-TPO levels compared to controls, with no significant difference in vitamin D levels.
54 citations
,
May 1994 in “Veterinary Pathology” This study found widespread localization of parathyroid hormone-related protein in normal and cancerous canine tissues, suggesting a potential physiological role as a paracrine or autocrine factor.
This observational study reviewed thyroid eye disease patients treated with teprotumumab at one center, reporting common side effects like fatigue and dry eye symptoms, with serious adverse events including two cases of blood clots and one pulmonary embolism.
4 citations
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January 1994 in “Current Opinion in Endocrinology & Diabetes” This review discusses multiple physiological roles of parathyroid hormone-related protein, such as cartilage mineralization and hair follicle regulation, and reports no new experimental results.
April 2020 in “Journal of the Endocrine Society” This case report describes a rare and atypical presentation of primary hypothyroidism with myxedema in a two-year-old boy, highlighting the importance of recognizing unusual symptoms for timely treatment.
November 2024 in “Neliti” This review discusses the difficulty of diagnosing hypothyroidism due to its diverse, nonspecific symptoms that can vary greatly among patients and often mimic other conditions, which may require healthcare providers to be vigilant across various specialties to recognize and diagnose the condition effectively.
October 2024 in “Journal of the Endocrine Society” This case report highlights that in severe illnesses like sepsis, myxedema coma can occur with less elevated TSH levels than typical for primary hypothyroidism, likely due to inflammatory cytokines affecting TSH secretion, even when central lesions are absent.
April 2026 in “Global Journal of Health Science” This study observed that patients with hypothyroidism-associated hair loss commonly have deficiencies in several vitamins and minerals, suggesting that these deficiencies may be linked to their condition.
50 citations
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January 1941 in “Annals of Internal Medicine” Idiopathic hypoparathyroidism is rare and can be managed with dihydrotachysterol.
January 2023 in “Radiation and Risk Bulletin of the National Radiation and Epidemiological Registry” In this study, heifers exposed to thyroid irradiation up to 30 Gy showed changes in thyroid hormone levels but tended toward recovery, without affecting immunity or productivity.
June 2023 in “British Journal of Dermatology” In this case report, researchers described a female child with total alopecia due to a mutation in the SNRPE gene, emphasizing the need for updated genetic testing as knowledge advances to avoid diagnostic delays in hereditary nonsyndromic hypotrichosis.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This case study describes a 41-year-old woman with a solitary thyroid nodule who underwent successful right hemithyroidectomy after initial suspicion of malignancy from ultrasound, later confirmed as benign colloid goiter via FNAC, highlighting the importance of thorough evaluation in thyroid conditions.
2 citations
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May 2017 in “Endocrinology, diabetes & metabolism case reports” This report describes a rare case of painless thyroiditis induced by prolonged off-label use of Lugol’s solution in a 59-year-old woman.
13 citations
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January 2021 in “Journal of Cellular and Molecular Medicine” This review discusses the roles and mechanisms of thymosin β4 in hair follicle growth and development but reports no new experimental findings; the authors emphasize the need for further research on its molecular pathways.
August 2018 in “Journal of The American Academy of Dermatology” Children with alopecia areata should only get thyroid screening if they have Down syndrome, a family history of thyroid disease, atopy, or signs of thyroid problems.
211 citations
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February 1994 in “Proceedings of the National Academy of Sciences” This study found that overexpression of parathyroid hormone-related peptide in transgenic mice skin disrupted normal hair follicle development, suggesting a role for the peptide in the early stages of follicle formation.
1 citations
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May 2021 in “Thyroid Research and Practice” This study found that low-dose radioactive iodine therapy for hyperthyroidism and thyroid cancer produced short-term adverse effects like loss of taste, xerostomia, and hair loss, which were self-limiting.
20 citations
,
September 2006 in “The Veterinary clinics of North America. Small animal practice/Veterinary clinics of North America. Small animal practice” This article reviews new drug therapies for endocrine disorders, discussing specific treatments such as trilostane for hyperadrenocorticism and various insulins for diabetes mellitus, but it reports no new clinical findings.
6 citations
,
April 1996 in “Journal of histochemistry and cytochemistry/The journal of histochemistry and cytochemistry” This study suggests that TGF-alpha may function in an autocrine or juxtacrine manner rather than promoting cell proliferation during hair growth cycles in ferrets and sheep.
35 citations
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October 2017 in “JAMA dermatology” This study recommends limiting routine thyroid function screening to children with alopecia areata who have medical histories of Down syndrome, atopy, or family histories of thyroid disease.
5 citations
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May 2019 in “Cureus” In this study, the authors reported that taking 20 mg or more of biotin can interfere with thyroid function tests, potentially leading to false diagnoses of conditions like Grave's disease.
October 2024 in “Eurasian Journal of Medicine” This study observed that among 81 children with Hashimoto's thyroiditis, girls were more affected than boys, with symptoms like neck swelling, fatigue, and hair loss frequently occurring, and most cases requiring treatment with levothyroxine.
12 citations
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December 1981 in “Journal of Endocrinology” This study found that α-melanocyte-stimulating hormone increased melanin production in hair follicles of moulting Siberian hamsters, whereas [8-arginine]-vasotocin inhibited melanin production without affecting tyrosinase activity.
31 citations
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July 2023 in “Nutrients” This article reviews evidence suggesting that vitamin D may help manage Hashimoto’s thyroiditis by affecting immune pathways and improving thyroid function, though more research is needed to fully understand its therapeutic potential.
11 citations
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March 1991 in “PubMed” This study found that in female patients with androgenic hair loss and hirsutism, complex hormonal disturbances include elevated cortisol and thyroid hormone imbalances, rather than elevated androgen levels alone.
51 citations
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December 2003 in “The FASEB Journal” This study reports that AS101 induced hair growth in mice and suggests potential for treating chemotherapy-induced alopecia in humans, which was observed in case report studies with three adolescents.
1 citations
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February 2025 in “Experimental Physiology” This study revisits the extensive contributions of Marie Krogh to thyroid physiology, highlighting her work that demonstrated resting metabolism changes in hyper- and hypothyroidism, her efforts to develop a thyroxine-like drug, and pioneering thyroid hormone research using guinea-pig models.
22 citations
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January 2013 in “International Journal of Trichology” Hair loss is often linked to thyroid problems, especially in women and older people, and screening for thyroid issues is advised for those with hair loss.
6 citations
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November 2010 in “Histochemistry and cell biology” This study found that transthyretin and megalin expression in human scalp hair follicles varies significantly with the hair growth cycle, peaking during anagen and diminishing in catagen and telogen phases.