98 citations
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December 2003 in “The FASEB Journal” In this study, thymosin beta4 was found to stimulate hair growth in normal rats and mice by affecting key processes in the hair follicle cycle, such as stem cell migration and extracellular matrix remodeling.
This study found that testosterone enhances glucose-stimulated insulin secretion in male and female human islets through its conversion to DHT and E2, a process disrupted by 5α-reductase and aromatase inhibitors.
November 2022 in “Journal of the Endocrine Society” This case study highlighted that excessive iodide intake from the supplement TauriNac was associated with the development of hypothyroidism in a cystic fibrosis patient, which reversed upon discontinuation.
October 2023 in “BMJ Case Reports” This case report describes a man diagnosed with Hoffman syndrome, characterized by muscle hypertrophy and weakness due to severe hypothyroidism, who had an excellent response to thyroid hormone replacement.
January 2008 in “Springer eBooks” Thyroid disease can cause hair loss and treating thyroid problems might help with hair disorders.
January 2025 in “Advances in Clinical Medicine” This article discusses the clinical and basic research on the use of traditional Chinese medicine external treatments for Hashimoto thyroiditis, highlighting accumulated experience despite not detailing specific study results.
13 citations
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January 2014 in “Journal of Veterinary Internal Medicine” This case study reports an instance of adult-onset primary hypothyroidism with goiter in a cat, suggesting potential causes such as dietary iodine imbalance, chronic exposure to thyrotoxic substances, or a congenital form with late manifestation.
12 citations
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January 1999 in “Journal of Animal Science” This study observed that combined treatment with thyroxine and hydrocortisone increased lipid accretion and fat cell development in hypophysectomized fetal pigs, suggesting a key role of these hormones in fetal adipogenesis.
January 2021 in “Acta Scientiae Veterinariae” In this study, researchers observed that administering the minimum dose of levothyroxine to a hypothyroid Dalmatian effectively restored normal skin condition and hormonal levels, suggesting levothyroxine's potential effectiveness in managing skin changes caused by hypothyroidism in dogs.
1 citations
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January 2013 in “INTAS POLIVET” In this case study, a Labrador dog diagnosed with hypothyroidism and treated with Thyroxine sodium, along with other supportive therapies, recovered completely from a generalized skin infection and alopecia within three months.
July 2025 in “International Journal of Homoeopathic Sciences” In this report, a 47-year-old woman with subclinical hypothyroidism experienced significant symptom relief and normalized TSH levels after six months of individualized homeopathic treatment with Sepia 1M, targeted to her symptom profile.
October 2012 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Thymic peptides can either promote or inhibit human hair growth.
April 2024 in “DAHUDER Medical journal” This study examined the relationship between thyroid autoimmunity and alopecia areata in patients aged 2-65 and found no statistically significant association, despite a notable correlation between anti-TPO levels and disease duration.
January 2022 in “Clinical Cases in Dermatology” This paper reviews treatment options for alopecia in hypothyroidism, noting that while hormone replacement can restore hair growth, additional treatments like PRP and oral minoxidil may help, though further research is needed.
2 citations
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May 2018 in “Journal of The American Academy of Dermatology” This study examined 15 female patients with hypothyroidism to investigate the characterization of their alopecia and ruled out other causes, using medical histories, and clinical, trichoscopic, and histologic findings.
26 citations
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October 2002 in “Journal of Investigative Dermatology” This study identifies a mutation in the hairless gene that may impact thyroid receptor interaction, contributing to alopecia universalis congenita in an Arab Israeli patient.
5 citations
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November 2021 in “Pediatrics in review” This review addresses the physiology, diagnosis, and management of thyroid dysfunction in children, focusing on conditions like hypothyroidism and hyperthyroidism, but presents no new clinical results.
12 citations
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July 1957 in “Journal of Investigative Dermatology” This historical observation found that parathyroid extract treatment in newborn rats led to a condition resembling scleroderma, characterized by skin hardening, calcium deposition, and possible necrosis.
February 2024 in “Folia Medica” In this study, PRP therapy showed effectiveness in treating mild to moderate alopecia areata in patients with normal antithyroid antibodies, while those with severe forms or elevated antibodies did not experience significant benefits.
1 citations
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October 2016 in “The American Journal of Gastroenterology” This case report highlights that celiac disease may cause levothyroxine malabsorption in patients with Hashimoto's thyroiditis, and a gluten-free diet can lead to improvement in thyroid hormone absorption.
284 citations
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May 2002 in “Proceedings of the National Academy of Sciences” In vitro, this study suggests that CRH may act as an autocrine hormone in human sebocytes, influencing lipid synthesis and potentially impacting skin disorders related to alterations in sebaceous lipid formation.
March 2026 in “Indian journal of veterinary and animal sciences research.” This case study found that treating a dog with primary hypothyroidism using oral levothyroxine sodium led to significant clinical improvement within six weeks.
November 2021 in “World Family Medicine Journal /Middle East Journal of Family Medicine” In this study, levothyroxine therapy showed no significant effect on blood sugar level changes in children with growth hormone deficiency in Saudi Arabia.
1 citations
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June 2021 in “Disease and Diagnosis” This case report describes a rare instance of Hashimoto thyroiditis evolving into Graves' disease, emphasizing the potential for such transitions and the importance of early diagnosis and treatment.
58 citations
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December 1992 in “British Journal of Dermatology” In this study, insulin-like growth factor-1 did not impact hair follicle elongation in rat pelage hair follicles, while transforming growth factor-beta 1 inhibited both elongation and thymidine uptake.
10 citations
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February 2017 in “International Journal of Rheumatic Diseases” This study observed that among rheumatoid arthritis patients, 22% had thyroid dysfunction, with hypothyroidism as the most common, and weight gain and cold intolerance were significant predictors.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this case study, a 41-year-old woman with a solitary thyroid nodule was found to have a benign colloid goiter after biopsy, and she successfully underwent right hemithyroidectomy with good postoperative recovery and management of symptoms using various supportive medications.
April 2023 in “Journal of Investigative Dermatology” Trichohyalin in hair can trigger immune attacks in alopecia areata.
November 2021 in “International Journal of Immunology and Microbiology” This study reported that treating alopecia patients with thyroxin tablets to reduce TSH levels, along with hair growth therapies, improved hair follicle growth and hair structure.
November 2023 in “Ibrahim Cardiac Medical Journal” This study observed that patients with alopecia areata have a significantly higher prevalence of thyroid disorders and elevated levels of thyroid-stimulating hormone and thyroid auto-antibodies compared to healthy individuals, with a 4.7 times greater risk of thyroid dysfunction among alopecia areata patients.