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Amenorrhea, or the absence of periods, should be evaluated by age 15 or within five years of early breast development, and is most commonly caused by conditions like polycystic ovary syndrome and hypothalamic amenorrhea.

People with pemphigus are more likely to have conditions like hypothyroidism, inflammatory bowel disease, and diabetes.

LC-MS/MS is more reliable than immunoassays for diagnosing 21-hydroxylase deficiency.

Comprehensive screening for infections is crucial before starting JAK inhibitors in alopecia areata patients.

Ashy dermatosis may be linked to atopy and thyroid disease and can be treated with topical steroids.

Doctors should actively prevent and treat skin side effects in cancer patients to keep them on the best medication and reduce discomfort.

Hormone imbalances can cause skin diseases, and understanding these links is important for diagnosis and treatment.

Stress, nutritional issues, and chronic diseases can cause hair loss, and nail changes may signal internal diseases; treatment focuses on the underlying cause.

Skin problems in older people can indicate hormonal diseases, nutritional deficiencies, or conditions like diabetes, menopause, and HIV.

A machine learning model called CATNIP can predict new uses for existing drugs, like using antidepressants for Parkinson's disease and a thyroid cancer drug for diabetes.

Vitiligo is a skin condition causing white spots, more common in women, often starts before age 20, and can affect mental health.

The conclusion is to thoroughly test for causes of cat hair loss and treat accordingly, considering medication only after serious conditions are ruled out.

Lichen planopilaris in men often involves scalp redness and itching, with some also having hair loss, mucosal lichen planus, or thyroid disease, and treatment improved symptoms in nearly half of the cases.

The document concluded that more research is needed to understand how estrogen affects the enzyme involved in hirsutism development.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

A woman with advanced eye cancer went into complete remission using a combination of immunotherapy and topical treatments.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

The document concludes that there have been significant improvements in diagnosing and treating skin diseases, including melanoma, with new techniques and therapies.

Damaged hair follicles make mice more prone to skin inflammation and skin cancer after UV exposure.

Activating Notch signaling can kill basal cell carcinoma cells.

Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.

People with myotonic dystrophy type 1 tend to develop basal cell carcinoma at a younger age but not more frequently than others.

Hedgehog pathway inhibitors used for skin cancer can cause significant hair loss, which may improve after stopping the medication.

People with Lichen planopilaris are more likely to have certain autoimmune and endocrine disorders but less likely to have conditions like allergies and diabetes.

Small hormonal imbalances can cause significant health problems, so more sensitive testing for hormone-disrupting chemicals is needed.

The study concluded that a new method can effectively assess scalp sun damage in balding men, which increases with age and sun exposure.

Changes in keratin affect skin health and can lead to skin disorders like blistering diseases and psoriasis.

Arsenic exposure from contaminated water severely damages the skin, causing hair loss, pigmentation changes, irritation, and can lead to skin cancer.

Dermoscopy is an effective tool for accurately detecting skin cancers.

Androgen suppression therapy (AST) doesn't significantly lower bladder cancer risk, but using finasteride, a type of AST, might decrease the risk. AST also lessens the chance of cancer coming back but doesn't really affect survival rates. More research is needed to understand AST's benefits for different bladder cancers.