Dermatopathology Update: 2013 Advancements in Diagnosis and Treatment of Skin Diseases

    March 2013 in “ Actas Dermo-Sifiliográficas ”
    María-Teresa Fernández-Figueras, Lluís Puig
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    TLDR The document concludes that there have been significant improvements in diagnosing and treating skin diseases, including melanoma, with new techniques and therapies.
    The 2013 document highlights advancements in dermatopathology, with a focus on improved diagnostic and treatment methods for skin diseases such as melanoma. It notes the increased use of molecular biology for genetic characterization of melanoma, the use of ultrasound scans and fine-needle aspiration cytology for better diagnosis and staging of tumors, and the introduction of targeted cancer therapies. Immunohistochemistry has seen progress with new antibodies, and there have been descriptions of new melanoma types and advancements in understanding various skin diseases. The document also discusses findings in inflammatory skin conditions, the characterization of primary cutaneous CD4+ small/medium-sized pleomorphic T-cell lymphoma, and diagnostic features in alopecia, including a new biopsy technique and the identification of a "follicular triad" for frontal fibrosing alopecia. Additionally, it mentions the use of Hedgehog pathway inhibitors for basal cell carcinoma and the validation of new cancer staging systems and markers for various skin cancers.
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