Screening for Latent Infectious Disease in Patients with Alopecia Areata Before Initiating JAK Inhibitors Therapy: A Single-Center Real-World Retrospective Study

    October 2023 in “ Frontiers in medicine ”
    Jundong Huang, Zhi‐Rong Tan, Yan Tang, Wei Shi
    Studysummary This study analyzed screening data from 218 alopecia areata patients before starting Janus kinase inhibitors, revealing the importance of pre-treatment screening due to risks of infections like tuberculosis and hepatitis B, with 74.8% of patients proceeding to treatment in real-world settings.
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    Research cited in this study 12

    1. Janus Kinase Inhibitors for Alopecia Areata Journal of the American Academy of Dermatology · 2023
    2. Efficacy and Safety of Ritlecitinib in Adults and Adolescents With Alopecia Areata: A Randomised, Double-Blind, Multicentre, Phase 2b–3 Trial The Lancet · 2023
    3. Hair Follicle Immune Privilege and Its Collapse in Alopecia Areata Experimental dermatology · 2020
    4. All-Cause and Cause-Specific Mortality Risks Associated With Alopecia Areata JAMA dermatology · 2019
    5. Comorbidities in Alopecia Areata: A Systematic Review and Meta-Analysis Journal of The American Academy of Dermatology · 2018
    6. Cancer Risk by the Subtype of Alopecia Scientific Reports · 2018
    7. Cancer Risk in Patients with Alopecia Areata: A Nationwide Population-Based Matched Cohort Study Cancer Medicine · 2018
    8. Alopecia Areata: Overview and Insights from January 2018 Journal of The American Academy of Dermatology · 2017
    9. Screening Guidelines for Thyroid Function in Children With Alopecia Areata JAMA dermatology · 2017
    10. Tofacitinib for the Treatment of Severe Alopecia Areata and Variants: A Study of 90 Patients Journal of The American Academy of Dermatology · 2016
    11. Health-Related Quality of Life Among Patients With Alopecia Areata: A Systematic Review Journal of The American Academy of Dermatology · 2016
    12. Alopecia Areata: An Autoimmune Disease Causing Hair Loss The New England Journal of Medicine · 2012

    Related research 2

    1. Treatment With Oral Janus Kinase Inhibitors in Adult Patients With Alopecia Areata: A Systematic Review and Meta-Analysis Journal of the American Academy of Dermatology · 2023
    2. Inhibiting Janus Kinases to Treat Alopecia Areata Nature medicine · 2014