3 citations
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February 2022 in “Canadian Medical Association Journal” This case report describes a 72-year-old man who developed symptoms of fatigue and cold intolerance after discontinuing his levothyroxine treatment for hypothyroidism six months earlier.
7 citations
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October 2020 in “Wiener medizinische Wochenschrift” This paper presents a case study of a 21-year-old male with thyroid hemiagenesis, where the left thyroid lobe and isthmus are absent, and discusses the anomaly's potential clinical consequences based on existing literature.
2 citations
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September 1993 in “PubMed” In this case report, a young man with primary hypothyroidism caused by autoimmune atrophic thyroiditis showed full recovery and normalization of metabolism after levothyroxine treatment.
29 citations
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July 2008 in “British Journal of Dermatology” This case report examines a patient with myasthenia gravis, invasive thymoma, and paraneoplastic pemphigus associated with alopecia areata, notably without the usual mucosal involvement.
October 2022 in “The American journal of gastroenterology” This case report details a patient with myasthenia gravis and a malignant thymoma whose rising liver function tests, initially thought to be related to antibiotic use, were ultimately attributed to thymoma-associated multiorgan autoimmunity.
April 2023 in “Zenodo (CERN European Organization for Nuclear Research)” In this report, a 35-year-old patient with beta thalassemia experienced thyroid dysfunction following repeated blood transfusions, highlighting that such disorders are common among transfused thalassemia patients.
February 2024 in “Internet Journal of Rheumatology and Clinical Immunology” This study examines a diagnostic case of SLE with atypical symptoms linked to thymoma-related multiorgan autoimmunity.
January 2024 in “Inflammation and regeneration” This study identified Th22 cells as key effectors in hair regeneration driven by thymosin beta 15, suggesting they could be potential targets for hair regrowth therapies.
110 citations
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April 2009 in “Cell Motility and the Cytoskeleton” This review discusses the intracellular activity of β-thymosins and their role in modulating the actin cytoskeleton, but it reports no new experimental results.
April 2023 in “World Journal of Advanced Research and Reviews” This case report describes common thyroid disorders in a β-thalassemia patient with frequent blood transfusions, emphasizing the need for monitoring thyroid function in such patients.
27 citations
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November 2000 in “Journal of Veterinary Medicine Series B” This study found that experimentally induced iodine deficiency in growing male lambs led to hypothyroidism, resulting in stunted growth, reduced wool production, and disrupted sexual maturity.
2 citations
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March 2019 in “Veterinary dermatology” The authors concluded that thymoma-associated paraneoplastic syndrome in cats may manifest as noninflammatory alopecia instead of exfoliative dermatitis, and should be considered when diagnosing multifocal noninflammatory alopecia.
May 2021 in “Journal of the Endocrine Society” In this case report, an established Hashimoto's thyroiditis patient converted to Graves disease, highlighting the need for regular monitoring and thyroid function tests to distinguish from potential levothyroxine over-replacement.
October 2016 in “Veterinary record case reports” This article describes a case of feline exfoliative dermatitis associated with a suspected thymoma, diagnosed using histopathology and imaging, and does not report new research findings beyond the case description.
July 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This case report from a pediatric setting highlighted how an 11-year-old with Hashimoto thyroiditis experienced atypical manifestations such as short stature, pubertal issues, and hair loss after starting levothyroxine therapy, underscoring the need for early diagnosis and multidisciplinary care to improve health outcomes.
2 citations
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June 2023 in “Clinical and Experimental Neuroimmunology” In this case study, the coexistence of thymoma-associated myasthenia gravis, alopecia areata, and twenty-nail dystrophy in a patient is reported, suggesting thymoma may increase the risk of developing these conditions.
October 2023 in “Journal of the Endocrine Society” In this case report, a shift from Hashimoto's thyroiditis to Graves' disease was observed in a 62-year-old woman, highlighting the rare transformation from hypothyroidism to hyperthyroidism over 20 years, possibly due to changes in antibody activity, according to the researchers.
October 2012 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Thymic peptides can either promote or inhibit human hair growth.
July 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this case report, an 11-year-old girl with hypothyroidism was found to have Hashimoto thyroiditis after presenting with hair loss, short stature, and pubertal disturbances; the study emphasizes the importance of early diagnosis and personalized thyroid hormone therapy for better outcomes.
11 citations
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January 1973 in “BMJ” This study reported that cortisone, testosterone, and thyroxine replacement therapy increased energy and hair growth, while decreasing cold sensitivity, in the absence of tumor recurrence.
13 citations
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January 2021 in “Journal of Cellular and Molecular Medicine” This review discusses the roles and mechanisms of thymosin β4 in hair follicle growth and development but reports no new experimental findings; the authors emphasize the need for further research on its molecular pathways.
July 2025 in “Journal of Investigative Dermatology” Androgens reduce THY1 in skin cells, leading to less fat, more fibrosis, and worse healing in males.
118 citations
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December 2003 in “Mechanisms of Ageing and Development” Thymosin β4 helps heal wounds, grow hair, and improve blood vessel formation.
July 2023 in “Indian Journal of Endocrinology and Metabolism” This case study reports that carbimazole therapy led to significant hair regrowth and a drop in thyrotropin receptor antibody levels in an 11-year-old girl diagnosed with alopecia areata and Graves' disease.
December 2014 in “Journal of Biomedical Research” In a mouse model of peripheral vascular disease, this study found that recombinant thymosin β4 treatment increased expression levels of certain proteins, promoting angiogenesis.
January 2010 in “The Internet Journal of Family Practice” This article reviews the clinical features, incidence, and systemic effects of hypothyroidism across different age groups and reports no new clinical findings.
35 citations
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June 2015 in “Pediatrics in Review” This article discusses hyperthyroidism in children, highlighting Graves' disease as the most common cause, and underscores the importance of timely diagnosis and intervention to mitigate morbidity; no new clinical results are reported.
October 2023 in “Pediatric blood & cancer” This report discusses a potentially underdiagnosed form of multisystem Langerhans cell histiocytosis in infants, demonstrating the use of thymic sonography for staging, highlighting a case where thymic and cutaneous involvement was confirmed, and suggesting thymic ultrasound may aid in better diagnosis and management of LCH.
June 2026 in “Journal of Investigative Dermatology” Aging weakens sweat glands due to reduced support from immune cells, but treatments may help restore function.
12 citations
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December 2022 in “Current Protein and Peptide Science” This review discusses the molecular mechanisms and clinical applications of thymosin β4, highlighting its potential benefits for inflammation, wound healing, tumor metastasis, and other medical conditions but reports no new experimental results.