Primary Hypothyroidism Presenting as Pituitary Failure

    January 1973 in “ BMJ
    W. M. G. Tunbridge, JohnR. Marshall, C. W. BURKE
    Studysummary This study reported that cortisone, testosterone, and thyroxine replacement therapy increased energy and hair growth, while decreasing cold sensitivity, in the absence of tumor recurrence.
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    The document described a case of primary hypothyroidism that initially presented as pituitary failure. In this case, plasma cortisol and growth hormone levels did not increase with induced hypoglycemia but did rise following vasopressin injection. The thyroid-stimulating hormone responded to thyrotrophin-releasing hormone administration. No tumor recurrence was observed during surgery. Replacement therapy with cortisone, testosterone, and thyroxine resulted in increased energy, hair growth, and reduced cold sensitivity in the patient.
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