research Acne Vulgaris
Acne vulgaris is a common skin condition that can cause low self-esteem and depression, and early treatment is important to prevent scarring.
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research Retinoids
Retinoids are effective for skin conditions like severe acne and psoriasis but must be used with caution due to potential side effects and risks during pregnancy.
research Role of Stem Cells in Skin Maintenance, Regeneration, and Repair: Focus on Epidermis and Pilosebaceous Units
The document concluded that stem cells are crucial for skin repair, regeneration, and may help in developing advanced skin substitutes.
research Evaluation of Hair Follicles as a Surrogate Tissue for Pharmacodynamic Response in Xenograft Tumors
Hair follicles can be used to quickly assess drug effects in cancer treatment.
research DNA Damage, Checkpoint Responses, and Cell Cycle Control in Aging Stem Cells
Maintaining DNA integrity in stem cells is crucial to prevent aging and cancer.
research Cutaneous Signals of Immune System Disease
Skin issues can indicate immune system problems.
research Medical Questions and Answers on Dermatological and Health Conditions
The document concludes that various skin conditions have specific treatments and that adequate calcium intake may prevent osteoporosis.
research The Autoimmune Regulator (AIRE), Defective in Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy Patients, Is Expressed in Human Epidermal and Follicular Keratinocytes and Associates With the Intermediate Filament Protein Cytokeratin 17
AIRE protein, defective in APECED patients, is found in skin and hair cells and interacts with cytokeratin 17.
research Cardiovascular Features in Adult Individuals Affected with Tatton-Brown-Rahman Syndrome
Adults with Tatton-Brown-Rahman syndrome may have serious heart problems and need lifelong heart monitoring.
research Exosomal MicroRNA-Based Therapies for Skin Diseases
miRNA-based therapies show promise for treating skin diseases, including hair loss, in animals.
research Tissue Resident Foxp3+ Regulatory T Cells: Sentinels and Saboteurs in Health and Disease
Foxp3+ Regulatory T Cells are important for immunity and tolerance, affect hair growth and wound healing, and their dysfunction can contribute to obesity-related diseases and other health issues.
research Netherton's Syndrome: A Syndrome of Elevated IgE and Characteristic Skin and Hair Findings
Netherton's syndrome is linked to high IgE levels and unique skin and hair symptoms, and may improve with ammonium lactate lotion and allergy management.
research Skin Cancer: Understanding the Transformation from Conventional to Advanced Treatment Approaches
New treatments like nanotechnology show promise in improving skin cancer therapy.
research Expression of Fox-Related Genes in the Skin Follicles of Inner Mongolia Cashmere Goat
Fox genes are important for hair growth and development in cashmere goats.
research Gene-Knockout Mice With Abnormal Epidermal and Hair Follicular Development
Knocking out certain genes in mice helps understand skin and hair growth problems.
research Matriptase Expression and Zymogen Activation in Human Pilosebaceous Unit
Matriptase is highly active in hair follicles and sebaceous glands, especially during hair growth phases.
research Cyclin D3 Deficiency Inhibits Skin Tumor Development But Does Not Affect Normal Keratinocyte Proliferation
Lacking cyclin D3 reduces skin cancer growth without affecting normal skin cell growth.
research The Microbiome in Patients with Atopic Dermatitis
People with atopic dermatitis have different skin bacteria, and targeting these bacteria might help treat the condition.
research Cannabinoid Signaling in the Skin: Therapeutic Potential of the Cutaneous Cannabinoid System
Cannabinoids may help treat various skin conditions.
research Clinical and Immunological Phenotype of Patients With Primary Immunodeficiency Due to Damaging Mutations in NFKB2
Damaging mutations in NFKB2 cause a severe and distinct form of primary immunodeficiency with early-onset and often ACTH-deficiency.
research Tyrosine Kinases in Autoimmune and Inflammatory Skin Diseases
Tyrosine kinases are important in skin autoimmune diseases and could be targets for new treatments.
research Pathology of Mouse Models of Accelerated Aging
Progeroid mouse models show signs of early aging similar to humans, helping us understand aging better.
research Germline Mutation in ATR in Autosomal-Dominant Oropharyngeal Cancer Syndrome
A specific ATR gene mutation is linked to a hereditary oropharyngeal cancer syndrome.
research Role of FGFR2-Signaling in the Pathogenesis of Acne
Increased FGFR2b signaling, influenced by androgens, plays a role in causing acne.
research Notch Signaling Regulates Late-Stage Epidermal Differentiation and Maintains Postnatal Hair Cycle Homeostasis
Notch signaling is essential for healthy skin and hair follicle maintenance.
research Proliferative and Non-Proliferative Lesions of the Rat and Mouse Integument
The project created a standardized system for classifying skin lesions in lab rats and mice.
research RANKL Induces Organized Lymph Node Growth by Stromal Cell Proliferation
RANKL causes lymph nodes to grow by making certain cells multiply.
research Mesenchymal Stromal Cell-Conditioned Medium for Skin Diseases: A Systematic Review
The review suggests that a special cell-derived treatment shows promise for various skin conditions and hair growth but needs more research for confirmation.
research Nagashima-Type Palmoplantar Keratosis: A Common Asian Type Caused by SERPINB7 Protease Inhibitor Deficiency
Nagashima-type palmoplantar keratosis in Asians is caused by a SERPINB7 gene mutation.
research New Developments in the Molecular Treatment of Ichthyosis: Review of the Literature
New treatments for ichthyosis, like protein replacement and gene therapy, show promise and may become standard care.