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The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.

Fat tissue-derived cells show promise for repairing body tissues, but more research and regulation are needed for safe use.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

New nanofiber technology improves wound healing by supporting cell growth and delivering treatments directly to the wound.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Blood vessels and specific genes help turn cartilage into bone when bones heal.

Fat cells in the skin help start healing and form important repair cells after injury.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

A wearable device using electric stimulation can significantly improve hair growth.

New methods for skin and nerve regeneration can improve healing and feeling after burns.

Mannosylerythritol lipids are good for skin and hair care products.

Smart biomaterials that guide tissue repair are key for future medical treatments.

HFMs can help study hair growth and test potential hair growth drugs.

Fat-derived stem cells, platelet-rich plasma, and biomaterials show promise for healing chronic skin wounds and improving soft tissue with few side effects.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

PRP injections may be a safe, effective alternative for hair loss treatment compared to minoxidil and finasteride.

Platelet-Rich Plasma (PRP) increases the number of new hair follicles and speeds up hair formation.

Multiphoton microscopy is a promising tool for detailed skin imaging and could improve patient care if its challenges are addressed.

Blocking Wnt signaling in young mice causes thymus shrinkage and cell loss, but recovery is possible when the block is removed.

Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.

Human liver cells stick to hair protein materials mainly through the liver's asialoglycoprotein receptor.

Polyamines help fix DNA damage accurately in cells.

Skin cell clumping for hair growth is improved by a protein called fibronectin, which helps cells stick and move better.

Microneedle arrays with nanotechnology show promise for painless drug delivery through the skin but need more research on safety and effectiveness.

Growing hair follicles have high mitochondrial activity and ROS in specific regions, aiding hair formation.

Using fat stem cells and blood cell-rich plasma together improves healing in diabetic wounds by affecting cell signaling.

Gene therapy has potential as a future treatment for Hutchinson-Gilford progeria syndrome.