1 citations
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January 2019 in “Turk Dermatoloji Dergisi” This study found that oxidative stress, measured through thiol/disulfide balance, is closely linked to the pathogenesis of telogen effluvium.
January 2019 in “AYBU AVESIS” In this study, individuals with androgenetic alopecia showed higher serum levels of oxidative stress markers and lower levels of antioxidants, indicating disrupted redox balance and suggesting oxidative stress may accelerate hair loss.
December 2021 in “Journal of Cosmetic Dermatology” This study found that thiol disulfide homeostasis is balanced in male patients with androgenetic alopecia, though oxidative stress may be more prominent with emotional stress and vitamin D deficiency.
September 2016 in “Journal of Engineering and Technological Science” Women with telogen effluvium have an imbalance in thiol-disulphide, suggesting oxidative stress may contribute to hair loss.
3 citations
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January 2019 in “International Journal of Trichology” This study found no statistical difference in thiol-disulfide balance between telogen effluvium patients and controls, suggesting oxidative stress may not affect telogen effluvium through this mechanism.
75 citations
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September 2015 in “Acta biomaterialia” This study found that alkylation of kerateine cysteine residues created a cell-compatible method for controlling hydrogel erosion rates and therapeutic agent release in keratin-based systems.
40 citations
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July 2015 in “Journal of Cellular Biochemistry” This study found that cysteine supplementation significantly increases keratin expression in human keratinocytes, and counteracts the negative impact of iron deficiency on keratin production by enhancing iron availability for cellular processes.
4 citations
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December 2013 in “Acupuncture and related therapies” This review summarizes the potential of N-acetyl-cysteine in managing diseases linked to redox imbalance, discussing its effects from cellular mechanisms to clinical applications, though further research is suggested for broader use.
6 citations
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October 2016 This article reviews the complex structure and molecular composition of hair keratins, highlighting their self-assembly process and implications for keratin extraction techniques, but reports no new experimental results.
18 citations
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July 2021 in “Molecular Medicine Reports” This review summarizes existing knowledge of how the WNT signaling pathway affects mesenchymal stem cells under various conditions, highlighting challenges and mechanisms for clinical applications.
9 citations
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March 2019 in “Molecular & cellular proteomics” In this study, around 1% of proteins in skin fibroblasts significantly changed in response to reductive stress, affecting collagens and MAPK signaling pathways.
July 2026 in “Advanced Science” In this study, researchers found that a scallop adhesive protein (Sbp9 Δ) forms strong adhesive coatings via disulfide-sticker strategies, which also promote hair regeneration in mouse models by activating Wnt signaling and enhancing angiogenesis, proving more effective than minoxidil for androgenetic alopecia.
April 2024 in “Research Square (Research Square)” This study found that bioconjugating 16-methylheptadecanoic acid (16-MHA) to damaged hair can mimic the protective properties of 18-methyleicosanoic acid (18-MEA), restoring the hair's structural integrity and moisture homeostasis, even after washing.
4 citations
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December 2020 in “Tissue Barriers” This review explores the immunological aspects of epidermal differentiation in loricrin knockout mice, offering insights into keratinization and potential intrinsic factors affecting immune function, but provides no new clinical findings.
April 2024 in “Advances in Redox Research” In this study, researchers found that polysulfides in human hair keratin contribute to hair strength and antioxidant capacity, with sulfur supplementation enhancing hair strength and cuticle structure amid oxidative stresses such as UV radiation.
10 citations
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August 2023 in “Advanced Science” This review discusses nitric oxide's physiological roles and the development of strategies for delivering it exogenously, without presenting new clinical results.
27 citations
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April 2020 in “Journal of Experimental Botany” This study found that glutathione deficiency affects lateral root and root hair responses to indole butyric acid in plants, but not to indole acetic acid, indicating its role in auxin pathway regulation.
37 citations
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March 2018 in “Trends in Plant Science” This review discusses the role of reactive oxygen species in regulating oscillating apoplastic pH gradients and growth in plant root hairs and pollen tubes, reporting no new experimental results.
166 citations
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November 2008 in “Expert Review of Endocrinology & Metabolism” This review discusses biotin and biotinidase deficiencies, their symptoms, and methods of medical management, without presenting new clinical findings.
August 2025 in “BMC Genomics” In this study, researchers found distinct gene expression patterns in Standardbred trotters capable of racing barefoot, suggesting a genetic basis for hoof strength and identifying specific genes involved in hoof biology, which could enhance equine performance and wellbeing through targeted genetic research.
7 citations
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September 2020 in “Journal of Cosmetic Dermatology” This study found that patients with androgenetic alopecia had increased oxidative stress and microinflammation, contributing to hair loss, due to elevated levels of specific serum biomarkers compared to controls.
August 2018 in “Biomedical Journal of Scientific & Technical Research” This study found that covalently binding antimicrobial agents to hair shafts provided antibacterial activity against dandruff and odor-associated bacteria, which remained effective even after several washes.
January 2025 in “Advances in Dermatology and Allergology” This study suggests that foods and drugs containing sulfhydryl groups may induce or worsen pemphigus vulgaris.
February 2026 in “Frontiers in Medical Technology” This review discusses current knowledge of keratinocyte stem cell dynamics, including their regenerative roles and potential applications beyond wound healing, but presents no new clinical findings.
This study explored the structure and function of lipocalin prostaglandin D synthase, revealing its dual role in substrate catalysis and as a lipophilic ligand carrier, potentially informing future drug delivery design.
9 citations
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May 2021 in “Molecules” This review discusses indole-based bifunctional aldose reductase inhibitors and antioxidants for diabetic complications and chronic inflammation-related pathologies, but reports no new clinical results.
January 2026 in “In Vivo” This study found that hidradenitis suppurativa is associated with an elevated risk of developing urolithiasis, suggesting shared inflammatory pathways and the need for vigilant kidney monitoring in affected individuals.
June 2025 in “Turkish Journal of Dermatology” This study found that patients with acne vulgaris had significantly lower serum paraoxonase 1 (PON1) activity compared to healthy controls, suggesting that oxidative stress might play a role in the condition's development.
March 2023 in “Journal of the turkish academy of dermatology” This study found that patients with onychomycosis had higher serum ceruloplasmin levels than healthy controls, which were also positively correlated with both disease duration and severity.
October 2023 in “Animal production science” This study investigated how vitamin A deficiency, certain diseases, and pregnancy affect cattle coat hair structure, finding notable keratin fibril interference under vitamin A deficiency and structural modifications in chronic renal failure, while pregnant cows exhibited superior hair tensile strength compared to non-pregnant ones.