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This study found that women with androgenic alopecia often have increased dihydrotestosterone levels, suggesting potentially enhanced activity of 5-alpha-reductase, with the saliva free testosterone level providing valuable hormonal background information.

This study describes a postmenopausal woman's diagnosis with ovarian hyperthecosis, confirmed by a GnRHa test normalizing testosterone, highlighting hormone therapy as a therapeutic option when surgery is not feasible.

This report describes a patient with trichothiodystrophy exhibiting both specific hair abnormalities and developmental delay, contributing to the understanding of this rare disorder's clinical presentation.

This study describes the enzymatic processes through which DHEA is converted to active sex steroids in human skin, highlighting an androgenic effect on sebaceous glands and estrogenic effects in the vagina.

In this study, researchers found that the thyroxine receptor agonist TDM10842 accelerated the onset of anagen, a hair growth phase, in C3H mice, potentially through activation of the Wnt/beta-catenin and Hedgehog pathways, with Pclaf playing a key role in this process.

This review examines the molecular mechanisms by which the proapoptotic protein ARTS inhibits tumorigenesis and discusses prospects for developing drugs that mimic its function, with no new experimental results reported.

This study found that administering adipose-derived stem cells with ATP improved hair regrowth in male mice with androgenetic alopecia, while the combination was less effective in female mice.

In this study, researchers demonstrated that CD4 T cells from skin-draining lymph nodes in mice with alopecia areata can transfer the disease to recipient mice, revealing a critical role for CD4 T cells in disease development and suggesting potential therapeutic targets.

This study found that treatment with cyproterone acetate and ethinylestradiol in hirsute women reduced testosterone and androstenedione levels, decreased hair growth, and increased cortisol levels without changing catecholamine excretion.

This study found that local androgen biosynthesis and metabolism in human sebaceous glands play a crucial role in sebum synthesis and secretion.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

This case report describes a 4.5-year-old boy with steroid-resistant nephrotic syndrome linked to X-linked recessive ichthyosis, where remission was achieved using cyclosporine, suggesting STS deficiency as a potential genetic cause of the condition.

GABAergic steroid precursors reduce ethanol withdrawal symptoms in certain mice.

This study reports that in a case of benign Brenner tumor, elevated androgens may originate from luteinized stromal cells, as these cells do not convert androgen to estrogen due to suppressed aromatase biosynthesis.

This study found that all-trans and 9-cis retinoic acids increase steroid sulfatase activity in HL60 cells through mechanisms involving RARα/RXR heterodimers and multiple signaling pathways.

This case report describes an unusual variant of Turner Syndrome in a 20-year-old female that required comprehensive medical and psychological care, including hormonal therapy that resolved symptoms like alopecia.

This review examines the negative effects of anabolic-androgenic steroid use on the male reproductive system, including impaired testosterone production, sperm production issues, and adverse metabolic consequences without reporting new clinical results.

This study found that cyproterone acetate, given with ethinyl oestradiol, significantly reduced hirsutism in women after 12 months, although improvements reversed once cyproterone acetate was stopped.

This study observed that combined treatment with thyroxine and hydrocortisone increased lipid accretion and fat cell development in hypophysectomized fetal pigs, suggesting a key role of these hormones in fetal adipogenesis.

This study found that Hashimoto's thyroiditis and alopecia areata show distinct gut microbial patterns, with specific microbes like Bacteroides fragilis and Microbacterium sp. T32 potentially linked to autoimmune activity.

This study used an in silico/in vitro approach to identify potential inhibitors of the enzyme SRD5A2, finding that the androgen receptor modulator MK-0773 is a moderate inhibitor, although it does not act as a covalent inhibitor like finasteride.

This case report details a functioning adrenocortical oncocytoma in a 3-year-old girl with hirsutism and virilization, highlighting its rarity in childhood and including a literature review without new clinical data.

This review discusses the role of anti-androgen therapies in cancer and other diseases and reports no new clinical results, highlighting both old and new generations of anti-androgens.

This article describes the DOAJ as a comprehensive index of diverse open access journals, emphasizing its commitment to freely providing quality content online, and reports no new findings.

HPT axis hormones boost mitochondrial function and growth in hair follicles, potentially aiding hair health.

This source describes clascoterone, a new topical treatment for acne vulgaris that blocks androgen receptors to reduce sebaceous gland activity and inflammation, offering a lower risk of systemic side effects compared to oral treatments.

This study introduced a novel nonsteroidal androgen receptor antagonist that effectively controls sebum production in the golden Syrian hamster ear model through targeted follicular delivery.

This study reports that TFM-4AS-1, a selective androgen receptor modulator, promoted bone and muscle growth with reduced effects on reproductive organs in ovariectomized rats.