January 2025 in “International Journal of Trichology” This case study reported transient localized hypertrichosis in a 26-year-old woman following cast removal from a forearm fracture, which resolved on its own after 5 months, suggesting that similar incidents of hair growth after trauma may have a benign and temporary course.
April 2017 in “Journal of Investigative Dermatology” In this study, HPH-15, a newly synthesized compound, demonstrated potential in reducing skin fibrosis in a mouse model by targeting underlying pathogenic mechanisms and exhibited a good safety profile, warranting further clinical trials for fibrotic skin disorders like systemic sclerosis.
215 citations
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November 2000 in “Journal of Investigative Dermatology” This study found that the tetracycline-regulated transcription system effectively controls conditional gene expression in the mouse epidermis, allowing suppression and activation of specific genes with doxycycline.
This study observed that stimulating the cholinergic system via muscarinic receptors in dermal papilla cells and other hair-related tissues promoted hair growth, with mechanisms involving the activation of Wnt/β-catenin signalling pathways in cell cultures and increased hair shaft elongation in mouse vibrissae treated with bethanechol.
11 citations
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September 1999 in “Journal of the European Academy of Dermatology and Venereology” This review examines various immunomodulatory therapies for cutaneous lymphoma and notes that they are most effective in the disease's early stages.
32 citations
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June 2021 in “Frontiers in Pharmacology” This study reports that Cur@CMCTS-Tk hydrogel effectively accelerated wound healing and tissue regeneration in rats by scavenging excess reactive oxygen species and protecting human fibroblasts from oxidative damage.
April 2024 in “Medicina Estética Revista Científica de la Sociedad Española de Medicina Estética (SEME)” This study clarifies the fundamental aspects of intradermotherapy or mesotherapy, tracing its historical development and highlighting its benefits as well as the negative consequences of improper use, specifically addressing its decline due to severe side effects from treatment errors.
245 citations
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October 2015 in “Nature medicine” The research found that hair follicle–derived cytokines, particularly IL-15 and IL-7, regulate skin-resident memory T cells and their role in both immune homeostasis and lymphoma in the skin.
36 citations
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January 2014 in “Elsevier eBooks” This narrative review discusses the structure and functions of the skin, focusing on its barrier role, self-repair, thermoregulation, and immune functions, and reports no new experimental results.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” This study reports that CD200R expression is significantly reduced in an experimental mouse model of scarring alopecia, suggesting a potential role for this pathway in immune regulation and hair follicle protection.
1 citations
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January 1989 This study produced and characterized four new monoclonal antibodies that specifically recognize differentiation antigens in human hair follicle and epidermal structures.
September 2025 in “Acta Biomaterialia” In this study, researchers developed injectable micropore-forming hydrogels that enhance tissue adhesion strength and promote wound healing by allowing better cell infiltration and inducing hair follicle regeneration in skin incision wound models.
April 2015 in “Plastic and Reconstructive Surgery” This article is from the ASPS Education Network and does not report any new research findings.
1 citations
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January 2025 in “Advances in Wound Care” This study identified dual epithelial and mesenchymal traits in dermal sheath cells during wound repair, suggesting they could be targeted to enhance healing.
21 citations
,
January 2018 in “Lasers in Medical Science” This study concluded that 12 sessions of fractionated thulium laser treatment improved hair density and thickness in patients with pattern hair loss, with further benefits from adding a growth factor solution post-treatment.
25 citations
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November 2015 in “Journal of Dermatological Science” In this study, researchers identified the antimicrobial peptide dermcidin in sebocyte lipid droplets, challenging the previous understanding of dermcidin as exclusively sweat-specific.
1 citations
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January 2000 in “Journal of pharmacopuncture” This study confirmed that microneedle therapy systems (MTS) significantly improve hair growth and skin conditions, including acne and acne scars, without serious side effects.
March 2019 in “Reactions Weekly”
This review discusses recent advances in using stem cells for skin repair and regeneration after severe burn injuries, but it reports no new clinical results.
January 2007 in “UKnowledge (University of Kentucky)” This study found that steers grazing on toxic tall fescue with continuous hair growth and reduced sweating had impaired thermoregulation, leading to decreased grazing activity and poor performance.
24 citations
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September 2014 in “PloS one” This study demonstrated that thyroid hormone receptors play a crucial role in hair growth and skin health, as mice lacking these receptors showed impaired hair cycling and wound healing.
26 citations
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January 1992 in “Carcinogenesis” This study suggests that chronic treatment with TPA in mouse skin selectively expands a keratinocyte subpopulation hyperinducible for ODC, which may be a key target for neoplastic transformation.
3 citations
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January 2019 in “Česká a slovenská farmacie” This review discusses various types of microneedles and their potential to expand the range of drugs delivered via the skin, but reports no new clinical results.
February 2022 in “Cosmetic Dermatology” Healthy skin prevents water loss and protects against threats.
1 citations
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December 2015 in “Dermatologic Surgery” Double trichophytic closure effectively treats thin scalp scars and reduces patient costs.
32 citations
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January 1971 in “Annals of Internal Medicine” This study observed that severe bronchitis may occur in individuals with anhidrotic ectodermal dysplasia when exposed to a dusty environment, potentially due to abnormalities in the bronchial mucosa.
77 citations
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January 1980 in “Carcinogenesis” This study found that TPA was significantly more effective than mezerein in inducing dark basal keratinocytes in mouse skin, which may be important in early tumor promotion stages.
February 1968 in “PubMed” This abstract explores the roles of dermal fibroblasts and keratinocytes in hair follicle neogenesis and regeneration but does not present new experimental results; it suggests more study is needed on the dermal sheath.
January 1990 in “The Nishinihon Journal of Dermatology” This study suggests that keratoacanthomas may be distinguished from squamous cell carcinoma by identifying hair follicle structures, based on keratin expression and histological features observed in tumor samples.
March 2026 in “Biomedicines” This review synthesizes current evidence on therapies for dissecting cellulitis of the scalp, noting that biologics show promise for treatment-resistant cases, though systemic retinoids remain the first-line therapy.