research FOXN1 Deficiency: From the Discovery to Novel Therapeutic Approaches
New treatments for immune disorders caused by FOXN1 deficiency are promising.
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research Inherited Epidermolysis Bullosa: Clinical and Therapeutic Aspects
The document concludes that inherited epidermolysis bullosa is a challenging genetic condition requiring multidisciplinary care and new treatments.
research Melatonin-Loaded Nanocarriers: New Horizons for Therapeutic Applications
Melatonin-loaded nanocarriers improve melatonin delivery and effectiveness for various medical treatments.
research Extra Virgin Olive Oil as Nutritional Therapeutic Immune Enhancer
Extra virgin olive oil may boost the immune system and help fight infections like COVID-19.
research The Effect of Cilostazol on Hair Growth: A Novel Therapeutic Option for the Treatment of Hair Loss
Cilostazol may help hair grow and could be a new treatment for hair loss.
research The Dihydrotestosterone Hypothesis of Prostate Cancer and Its Therapeutic Implications
The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.
research Harnessing Neuroendocrine Controls of Keratin Expression: A New Therapeutic Strategy for Skin Diseases?
Using neurohormones to control keratin can lead to new skin disease treatments.
research A Cell Membrane-Level Approach to Cicatricial Alopecia Management: Is Caveolin-1 a Viable Therapeutic Target in Frontal Fibrosing Alopecia?
Targeting the protein Caveolin-1 might help treat a type of scarring hair loss called Frontal Fibrosing Alopecia.
research Epidermal Stem Cells Manipulated by pDNA-VEGF165/CYD-PEI Nanoparticles Loaded Gelatin/β-TCP Matrix as a Therapeutic Agent and Gene Delivery Vehicle for Wound Healing
The gelatin/β-TCP scaffold with nanoparticles improves wound healing and skin regeneration.
research The Phenotype of Circulating Follicular-Helper T Cells in Patients with Rheumatoid Arthritis Defines CD200 as a Potential Therapeutic Target
Targeting CD200 could be a new treatment for rheumatoid arthritis.
research Therapeutic Potential of Hair Follicle-Derived Stem Cell Intranasal Transplantation in a Rat Model of Ischemic Stroke
Transplanted hair follicle stem cells improved brain function and reduced damage after a stroke in rats.
research Dissolving Microneedles: Applications and Growing Therapeutic Potential
Dissolving microneedles show promise for delivering medication through the skin but face challenges like manufacturing complexity and regulatory hurdles.
research TGFβ and Cancer Metastasis: An Inflammation Link
TGFβ's manipulation of inflammation and immune cells affects cancer spread, suggesting new treatment strategies and biomarkers.
research Hormonal Manipulation of Benign Prostatic Hyperplasia
Finasteride and dutasteride are equally effective and safe for treating benign prostatic hyperplasia.
research Therapeutic Effects of Stem Cells in Different Body Systems: A Comprehensive Review
Stem cell therapy is promising for treating various health conditions, but more research is needed to understand its full potential and address challenges.
research Targeting Smoothened for Therapeutic Gain
Targeting the Smoothened receptor shows promise for treating certain cancers.
research Crafting Polymeric and Peptidic Hydrogels for Improved Wound Healing
Advanced hydrogel systems with therapeutic agents could greatly improve acute and chronic wound treatment.
research Adult Female Acne: Clinical and Therapeutic Particularities
Adult female acne is complex and requires a combination of treatments for effective management.
research Stem Cell-Derived Exosomes: Emerging Therapeutic Opportunities for Wound Healing
Tiny vesicles from stem cells could be a new treatment for healing wounds.
research Effects of Dobutamine on Cyclic AMP Accumulation Induced by the Stimulation of Dopamine Receptors in Rabbit Retina In Vitro
Dobutamine does not mimic dopamine at therapeutic doses but may at very high concentrations; microfilaments, not microtubules, are important for wound healing in Xenopus embryos.
research Exploiting the Origins of Ras-Mediated Squamous Cell Carcinoma to Develop Novel Therapeutic Interventions
Researchers found that hair follicle stem cells can become squamous cell carcinoma due to Ras activation, which could lead to new treatments.
research In Vitro and Ex Vivo Hair Follicle Models to Explore Therapeutic Options for Hair Regeneration
New methods to test hair growth treatments have been developed.
research Dysregulated Behavior of Hair Follicle Stem Cells Triggers Alopecia and Provides Potential Therapeutic Targets
Misbehaving hair follicle stem cells can cause hair loss and offer new treatment options.
research Wnt/β-Catenin Signaling: Function, Biological Mechanisms, and Therapeutic Opportunities
The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.
research Hair Follicle Stem Cells: Walking the Maze
Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.
research Gonadal Sex Steroids: Production, Action, and Interactions in Mammals
The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.
research Development of an Intrinsic Skin Sensor for Blood Glucose Level with CRISPR-Mediated Genome Editing in Epidermal Stem Cells
Researchers created a skin graft that senses blood glucose and could treat diabetes using CRISPR-edited stem cells.
research The Nuclear Vitamin D Receptor: Biological and Molecular Regulatory Properties Revealed
The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.
research Hidradenitis Suppurativa: Pathogenesis and Management
Hidradenitis suppurativa, a chronic skin disease, can be managed with antibiotics, lifestyle changes, and in severe cases, surgery. Early diagnosis and careful planning are key, and laser treatment can be an efficient solution for mild to severe cases.
research Learning From Nudity: Lessons From The Nude Phenotype
The Foxn1 gene mutation causes hairlessness and immune system issues, and understanding it could lead to hair growth disorder treatments.