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FOXN1 gene mutations cause a rare, severe immune disease treatable with cell or tissue transplants.

Minoxidil and finasteride combo maintains hair density effectively.

Antiandrogens can help treat skin conditions like acne and excessive hair in women when used carefully.

Hormonal treatments are effective as a second-line option for moderate-to-severe acne in females, but should be used with caution due to health risks.

Fully regenerating human hair follicles not yet achieved.

Rats had lasting erectile problems after stopping a certain medication.

Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.

Finasteride poorly inhibits type 1 5AR, affecting its effectiveness.

New treatments for psoriasis have improved effectiveness and may reduce long-term side effects when combined with standard therapies.

GMG-43AC may help reduce unwanted hair growth and treat certain hair loss conditions.

Gene therapy, especially using atoh1, shows promise for creating functional sensory hair cells in the inner ear, but dosing and side effects need to be managed for clinical application.

AIRE-deficient rats developed severe autoimmune disease similar to APECED, useful for testing treatments.

Antidepressants might help with skin inflammation and improve conditions like psoriasis and eczema.

PEVs effectively deliver minoxidil through skin.

Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.

Minoxidil in HA-PLGA nanoparticles effectively treats alopecia through skin delivery.

Chitosan/LiCl composite scaffolds help heal deep skin wounds better.

Skin lymphatic vessels are essential for hair growth.

Testosterone therapy can help improve mood, sexual function, and bone health in women with low androgen levels, but more research is needed to establish safe and effective guidelines.

Liposomes can make the antiandrogen RU 58841 more effective for skin application by reducing absorption, increasing skin retention, and targeting sebaceous structures.

Androgen excess disorders in women were effectively treated with spironolactone, estrogen, and dexamethasone.

Quercetin-loaded nanoparticles can penetrate skin, minimize hair loss, and promote hair regrowth, showing slightly better results than a marketed product.

The document concludes that PK/PD modeling is important for determining the safe and effective dosages of drugs.

Taking metformin with intense-pulsed-light therapy improves hair removal for people with PCOS.

A compound made by Pfizer can potentially stimulate hair growth and reduce oil production, making it a good candidate for topical use.

The document concludes that low-dose oral contraceptives and hormonal therapies can manage perimenopause symptoms and reduce some health risks, but lifestyle changes and disease screening are also important.

Minoxidil can stop the growth of ovarian cancer cells without harming the heart.

Scientists created keratinocyte cell lines from human hair that can differentiate similarly to normal skin cells, offering a new way to study skin biology and diseases.

RNA aptamers can specifically block FGF5-related cell growth, potentially treating related diseases or hair disorders.

Tofacitinib nanoparticles can safely and effectively treat alopecia areata by targeting hair follicles.