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DHT affects hair follicle cells by changing microRNA levels, leading to less cell growth and more cell death.

Allopregnanolone is needed for certain brain processing issues caused by D1 dopamine receptor activation.

Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

Male rats have more somatostatin neurons than females due to testosterone converting to estrogen during early development.

The new oral testosterone pill normalized testosterone levels and lowered SHBG in men with low testosterone.

Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Finasteride affects frog testes by increasing testosterone, decreasing 5α-DHT, and impacting genes related to reproduction and other functions.

Nandrolone and oxandrolone could help treat male health issues like muscle loss and low testosterone.

Exposure to finasteride in the womb caused lasting reproductive issues in male rats.

New treatments for male hypogonadism are effective and should be personalized.

Finasteride effectively treats male pattern baldness, improving hair growth and density.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

Benign Prostatic Hyperplasia may be caused by changes in how the body processes male hormones.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

Germacrene analogs, especially 8-Hydroxy germacrene B, are more effective than germacrone at blocking a hormone-related enzyme and could help treat hair loss.

Different substances that activate or block the androgen receptor can affect male development and treat conditions like prostate cancer.

Saw palmetto may cause erectile dysfunction and needs better safety monitoring.

Changes in skin bacteria can affect hair loss and new treatments targeting these bacteria may prevent balding without sexual side effects.

Hormones, especially testosterone and DHT, are key for penis development and function, and testosterone therapy may help with erectile dysfunction in those with low levels.

Androgens can both increase and decrease hair growth in different parts of the body.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.

Gonadal dysgenesis, like Turner's and Klinefelter's syndromes, negatively affects bone health, but hormone treatments can help.

The document explains hair biology, the causes of hair loss, and reviews various hair loss treatments.

Women's ovarian hormones and adrenal androgens change throughout life, affecting hair loss and health.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

Hormones and genetics play key roles in male and female baldness, which can affect mental health and may be linked to other health issues.