research Androgen Receptor-Mediated Inhibition of Cutaneous Wound Healing
Blocking testosterone speeds up wound healing in males.
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research Species Differences in Prostatic Steroid 5α-Reductases of Rat, Dog, and Human
Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.
research Dihydrotestosterone and the Concept of 5-Alpha-Reductase Inhibition in Human Benign Prostatic Hyperplasia
Blocking the enzyme that turns testosterone into DHT can safely and effectively treat enlarged prostate.
research Androgen Biosynthetic Pathways in the Human Prostate
DHT in the human prostate is produced through multiple pathways, not just from testosterone.
research Effects of Finasteride (MK-906), a 5α-Reductase Inhibitor, on Circulating Androgens in Male Volunteers
Finasteride safely lowers DHT levels without affecting testosterone.
research Effects of Flutamide and Finasteride on Rat Testicular Descent
Androgens, like testosterone, are crucial for early testicular descent in rats.
research The Effects of Two Doses of Spironolactone on Serum Androgens and Anagen Hair in Hirsute Women
Spironolactone reduced hair thickness and some testosterone levels in women with excessive hair growth.
research The Influence of Androgens on Insulin Resistance
Higher levels of unbound testosterone are linked to increased insulin resistance, especially in women with polycystic ovary syndrome.
research Investigation, Treatment, And Monitoring Of Late-Onset Hypogonadism In Males: ISA, ISSAM, And EAU Recommendations
Men with low testosterone should be carefully evaluated and monitored before and during treatment.
research Androgen Receptor-Mediated Inhibition of Cutaneous Wound Healing
Lowering testosterone speeds up wound healing in male mice.
research Hormonal Effects on Hair Follicles
Hormones like testosterone and estrogen significantly affect hair growth and structure.
research Endocrine Aspects of Female Sexual Dysfunction
Hormones like estrogen, testosterone, progesterone, and prolactin play complex roles in female sexual function, with testosterone potentially improving sexual desire, arousal, and satisfaction. However, more research is needed to establish safe and effective hormone treatments for female sexual dysfunction.
research The Antiandrogenic Action of 4-Androsten-3-One-17β-Carboxylic Acid and Its Methyl Ester on Hamster Flank Organ
The chemicals 17βC and its methyl ester can block the effects of testosterone on hamster skin but not the effects of DHT.
research Genome-Wide Association Study Identifies a New Locus JMJD1C at 10q21 That May Influence Serum Androgen Levels in Men
A new gene, JMJD1C, may affect testosterone levels in men.
research Androgens and Female Sexual Function and Dysfunction—Findings From the Fourth International Consultation of Sexual Medicine
Androgens play a role in female sexual function, and testosterone therapy can help women with low sexual desire, but more research is needed on treatments and long-term safety.
research Physiology of the Hypothalamic Pituitary Gonadal Axis in the Male
The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.
research Steroidogenesis of the Testis: New Genes and Pathways
New genes and pathways are important for testosterone production and male sexual development.
research Anti-Androgenic Activities of Ganoderma Lucidum
Ganoderma lucidum, a type of mushroom, may help treat enlarged prostate by blocking testosterone conversion.
research Anti-Androgenic Activities of the Triterpenoids Fraction of Ganoderma Lucidum
The triterpenoids from Ganoderma lucidum can block testosterone effects and may help treat enlarged prostate.
research Hypogonadism as a Reversible Cause of Torsades de Pointes in Men
Low testosterone can cause a heart rhythm problem in men, but fixing it can prevent the issue.
research Clinical, Metabolic, and Endocrine Parameters in Response to Metformin and Lifestyle Intervention in Women with Polycystic Ovary Syndrome: A Randomized, Double-Blind, and Placebo-Controlled Trial
Metformin combined with lifestyle changes improves insulin resistance and reduces testosterone levels in women with PCOS more than lifestyle changes alone.
research Epitestosterone: Regulatory Roles in Androgen-Dependent Processes
Epitestosterone may counteract testosterone's effects and has roles in body processes like prostate growth and hair distribution.
research Regulatory Roles of Androgens in Cutaneous Wound Healing
Testosterone may slow down wound healing and increase inflammation.
research The Dihydrotestosterone Hypothesis of Prostate Cancer and Its Therapeutic Implications
The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.
research Dihydrotestosterone Stimulates 5α-Reductase Activity in Pubic Skin Fibroblasts
Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.
research Male Androgenetic Alopecia
DHT, a testosterone byproduct, causes male pattern baldness.
research Hair Follicles and Associated Glands as Androgen Targets
Androgens like testosterone affect hair growth and oil production differently across body parts and individuals.
research Effects of a Low-Dose Desogestrel-Ethinylestradiol Combination on Hirsutism, Androgens, and Sex Hormone Binding Globulin in Women with Polycystic Ovary Syndrome
Low-dose oral contraceptives reduced hair growth and testosterone levels in women with polycystic ovary syndrome.
research Anti-Androgenic Activity of Myricae Cortex: Isolation of Active Constituents from Bark of Myrica Rubra
The bark of Myrica rubra contains compounds that can block testosterone effects and might help prevent hair loss.
research The Effect of Spironolactone on Genital Skin 5α-Reductase Activity
Spironolactone reduces the enzyme activity that converts testosterone to DHT, helping treat excessive hair growth in women.