53 citations,
October 1984 in “Endocrine reviews” Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.
52 citations,
November 2013 in “European Journal of Pharmaceutical Sciences” Chitosan-decorated polymersomes improve finasteride delivery for hair loss treatment.
51 citations,
May 2013 in “The Journal of Steroid Biochemistry and Molecular Biology” Certain drugs that block specific enzymes can help treat prostate diseases.
50 citations,
November 2010 in “Plastic and Reconstructive Surgery” Botox increased hair count in men with baldness and might work by improving scalp blood flow.
49 citations,
June 1998 in “Journal of Endocrinological Investigation” Cyproterone acetate plus ethinyl estradiol is generally more effective in treating hirsutism, but consider side effects and patient characteristics.
48 citations,
January 2017 in “Skin Pharmacology and Physiology” Finasteride-loaded nanoparticles may help treat alopecia.
47 citations,
February 2014 in “Aaps Pharmscitech” Improved hair loss treatment using special particles and surfactants.
44 citations,
October 2011 in “Gynecological Endocrinology” Menopause significantly reduces skin collagen, leading to thinner, less elastic skin, and hormone replacement may help but requires careful consideration.
42 citations,
May 2013 in “Oral Diseases” Kennedy's disease leads to muscle weakness without a cure, but exercise and managing symptoms may help patients live a normal lifespan.
42 citations,
January 2014 in “Cold Spring Harbor Perspectives in Medicine” Hair growth is influenced by various body and external factors, and neighboring hairs communicate to synchronize regeneration.
37 citations,
October 2006 in “Steroids” New sulfur-containing steroid analogs show promise for more targeted medical treatments.
37 citations,
November 1995 in “Journal of Investigative Dermatology” Topical finasteride and flutamide reduce gland size and enzyme activity, with flutamide being more potent, potentially treating acne, seborrhea, hirsutism, and androgenic alopecia.
35 citations,
May 2012 in “Expert Opinion on Pharmacotherapy” The document concludes that there are various treatments for different types of alopecia, but more research is needed for evidence-based treatments.
34 citations,
November 2013 in “Breast Cancer Research and Treatment” Aromatase inhibitor therapy for breast cancer increases the risk of hair loss and thinning.
33 citations,
May 2013 in “Andrologia” Some herbs show promise as antiandrogenic agents.
33 citations,
January 2009 in “Contraception” Chlormadinone acetate is a strong, well-tolerated hormone used in birth control and hormone therapy with benefits for menstrual pain and skin conditions.
31 citations,
March 2015 in “The Journal of Steroid Biochemistry and Molecular Biology” Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.
30 citations,
April 1997 in “European journal of endocrinology” The document concludes that managing hirsutism involves identifying the cause, using a scoring system for severity, combining cosmetic and medical treatments, encouraging weight loss, and providing psychological support, while noting the need for more research on drug treatments.
29 citations,
July 2012 in “The Journal of Sexual Medicine” Rats had lasting erectile problems after stopping a certain medication.
28 citations,
November 2007 in “Medical Clinics of North America” Obesity worsens Polycystic Ovary Syndrome symptoms, and weight loss is a key treatment.
28 citations,
January 1991 in “Reproductive Toxicology” Finasteride temporarily lowers male rat fertility without affecting libido.
27 citations,
October 2016 in “The Journal of Clinical Endocrinology and Metabolism” Daughters of women with PCOS generally experience normal puberty but may have more body hair and different body fat distribution.
27 citations,
January 1984 in “Pharmacology & Therapeutics” Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.
27 citations,
November 1998 in “Journal of Endocrinological Investigation” Finasteride significantly reduces hair growth in women with idiopathic hirsutism.
26 citations,
December 2019 in “Neurobiology of Stress” Post-finasteride syndrome causes lasting sexual, neurological, and physical side effects in some people after taking finasteride.
25 citations,
November 2014 in “Ageing Research Reviews” Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.
25 citations,
January 2000 in “Hormone Research in Paediatrics” Mutations in the androgen receptor gene cause Androgen Insensitivity Syndrome, affecting sexual development.
25 citations,
June 2017 in “Molecular and Cellular Endocrinology” Using anabolic androgenic steroids can cause serious, lasting health problems in many parts of the body.
23 citations,
December 2012 in “ChemistryOpen” Probe detects finasteride with high selectivity and low detection limit.
22 citations,
March 2020 in “Cosmetics” Nanotechnology improves minoxidil treatment for hair loss.