research Effects of Non-Contingent Cocaine on 3alpha-Androstanediol: Disruption of Male Sexual Behavior
Cocaine impairs male sexual behavior and alters testosterone metabolism in the brain.
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research Rare Presentation of Precocious Puberty Secondary to LH-Secreting Adenoma
An 8-year-old boy's early puberty was caused by a rare hormone-secreting brain tumor, which was successfully treated with surgery.
research Androgen Receptor Ligands: Agonists and Antagonists
Different substances that activate or block the androgen receptor can affect male development and treat conditions like prostate cancer.
research Observation of Phenotypic Variation Among Indian Women With Polycystic Ovary Syndrome (PCOS) From Delhi and Srinagar
Indian women with PCOS from Delhi and Srinagar show different symptoms, with Delhi women having higher obesity and blood sugar issues, and Srinagar women showing more hair growth and testosterone levels.
research Relationship Between Plasma Sex Hormones and Severity of Coronary Artery Disease
Lower testosterone levels in men may be linked to a higher risk of severe coronary artery disease.
research Serum Testosterone And Dihydrotestosterone And Incidence And Progression Of Lower Urinary Tract Symptoms: Results From The Reduce Study
Higher testosterone and DHT levels are not linked to urinary symptoms in men.
research Effect of Lifestyle Modifications on Reproductive Function Among Infertile Obese Women with Polycystic Ovarian Syndrome
Lifestyle changes improve reproductive function and hormonal balance in obese women with PCOS.
research Prevalence and Predictors of Impaired Glucose Tolerance and Type 2 Diabetes Mellitus in Patients with Polycystic Ovary Syndrome
Many women with polycystic ovary syndrome have normal blood sugar, but some may have higher blood sugar levels or diabetes, especially if they are older, overweight, and have certain hormone levels.
research Testosterone: Functions, Uses, Deficiencies, and Substitution
Testosterone is important for male development and health, and careful replacement can treat low levels.
research Effect of Petroleum Ether and Ethanol Fractions of Seeds of Abrus Precatorius on Androgenic Alopecia
The seeds of Abrus precatorius, when processed, can prevent hair loss more effectively than common treatments.
research Short- and Long-Term Clinical Skin Effects of Testosterone Treatment in Trans Men
Testosterone treatment in trans men increases body and facial hair and may lead to hair loss over time, but severe skin issues are rare.
research Testosterone in COVID-19: An Adversary Bane or Comrade Boon
Testosterone's effects on COVID-19 are unclear and need more research.
research Biochemical Roles of Testosterone and Epitestosterone to 5α-Reductase as Indicators of Male-Pattern Baldness
High testosterone to epitestosterone ratio in hair could predict male-pattern baldness.
research Determination of Some Sex Hormones in Health Supplements by Liquid Chromatography with Tandem Mass Spectrometry
The method detected sex hormones in some health supplements, with one containing banned testosterone.
research Dihydrotestosterone Induces Arterial Stiffening in Female Mice
Dihydrotestosterone makes arteries stiffer in female mice by reducing estrogen receptor expression.
research Selective Induction of Apoptosis in the Hamster Flank Sebaceous Gland Organ by a Topical Liposome 5-Alpha-Reductase Inhibitor: A Treatment Strategy for Acne
A topical treatment safely and effectively reduced acne by causing targeted cell death in sebaceous glands without side effects.
research Incidence of Female Androgenetic Alopecia (Female Pattern Alopecia)
Female pattern alopecia is common, starts in late 20s, and is not androgen dependent.
research Structural Basis for the Catalysis and Inhibition of Human Steroid 5α-Reductase 2
The research gives new understanding on how human steroid 5α-reductases work and how drugs like finasteride inhibit them, which could help in creating new drugs.
research Features of Hyperandrogenism in Men
Androgen levels can increase at any age, affecting symptoms like acne, hair loss, and prostate size.
research Cardiovascular Risk in Women with Premature Ovarian Insufficiency Compared to Premenopausal Women at Middle Age
Women with premature ovarian insufficiency have a worse cardiovascular risk profile than premenopausal women.
research A Clinical Study of the Effects of Finasteride on Androgenetic Alopecia
Finasteride effectively treats hair loss in men with minimal side effects.
research Cardiac and Brainstem Neuroinflammatory Pathways Account for Androgenic Incitement of Cardiovascular and Autonomic Manifestations in Endotoxic Male Rats
Testosterone plays a big role in heart and nervous system damage caused by inflammation in male rats, suggesting that blocking testosterone production could help manage this condition.
research Evaluation of the Role of Soluble Receptors for Advanced Glycosylated End-Products in Polycystic Ovarian Syndrome
Women with PCOS had higher SRAGE levels, possibly linked to BMI, not PCOS.
research Hospitalists for the NHS: The Role of Androgens and Antiandrogen Therapy in Hidradenitis Suppurativa
Antiandrogen therapy may help treat hidradenitis suppurativa.
research Development of a Liquid Chromatography/Mass Spectrometry-Based Inhibition Assay for Screening Steroid 5-Alpha Reductase in Human and Fish Cell Lines
A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.
research Effects of Sex Steroid Deprivation and Administration on Hair Growth and Skin Sebum Production in Transsexual Males and Females
Hormone treatments in transsexual individuals reduce hair growth and oil production in male-to-females and increase them in female-to-males.
research Investigation, Treatment, And Monitoring Of Late-Onset Hypogonadism In Males: ISA, ISSAM, And EAU Recommendations
Men with low testosterone should be carefully evaluated and monitored before and during treatment.
research Female Androgenetic Alopecia: A Separate Entity
Female and male AGA are different diseases.
research Androgenetic Alopecia and Microinflammation
Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.
research Effects of the Anti-Androgen Finasteride on 5α-Reduction of Androgens in the Presence of Progesterone in Human Gingival Fibroblasts: Modulatory Actions of the Alkaline Phosphatase Inhibitor Levamisole
Finasteride reduces testosterone conversion, progesterone lessens this, and levamisole enhances finasteride's effect.