research The Latest Options and Future Agents for Treating Male Hypogonadism
New and future treatments for male hypogonadism include various forms of testosterone therapy and emerging drugs.
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research Scalp Hair Regrowth in Hormone-Treated Transgender Woman
Hormone therapy with estradiol and spironolactone can regrow scalp hair in transgender women by lowering testosterone to female levels.
research Detection of Urine Metabolites in Polycystic Ovary Syndrome by UPLC Triple-TOF-MS
Researchers found potential urine markers for polycystic ovary syndrome, including testosterone-glucuronide and 11α-hydroxyprogesterone, which may help diagnose the condition.
research Circulating Androgen Levels Before and After Oophorectomy in Premenopausal and Postmenopausal Women
Oophorectomy lowers testosterone and estrogen levels in both premenopausal and postmenopausal women, with postmenopausal women still producing significant testosterone.
research The Hirsute Woman: Challenges in Evaluation and Management
Most hirsutism cases are due to PCOS, and treatment focuses on lowering testosterone and blocking its effects.
research New Progesterone Esters as 5α-Reductase Inhibitors
Some new progesterone derivatives are better at blocking testosterone conversion than a common drug.
research Effects of Finasteride, a 5 Alpha-Reductase Inhibitor, on Circulating Androgens and Gonadotropin Secretion in Hirsute Women
Finasteride reduces dihydrotestosterone, increases testosterone, and may treat hirsutism in women.
research Chromium Supplementation in Women with Polycystic Ovary Syndrome: Systematic Review and Meta-Analysis
Chromium supplements don't improve insulin, hormone levels, or cholesterol in women with PCOS but raise testosterone levels.
research Detection of Male Hypogonadism in Patients with Post COVID-19 Condition
Nearly half of the studied men with long COVID had low testosterone, including younger men.
research Postmenopausal Virilization After Spousal Use of Topical Androgens
A woman developed male traits from accidental contact with her husband's testosterone gel.
research What Is the Rationale for Androgen Therapy for Women?
Testosterone therapy can help improve mood, sexual function, and bone health in women with low androgen levels, but more research is needed to establish safe and effective guidelines.
research Are Sex Hormones Promising Candidates to Explain Sex Disparities in the COVID-19 Pandemic?
Sex hormones like estrogen and testosterone may affect COVID-19 severity differently in men and women, potentially influencing prevention and treatment strategies.
research Polycystic Ovary Syndrome and the Differential Diagnosis of Hyperandrogenism
The document concludes that careful evaluation is needed to diagnose PCOS correctly due to similar symptoms in other conditions, and accurate testosterone level measurement is crucial.
research Curcumin Derivatives Inhibit Testicular 17β-Hydroxysteroid Dehydrogenase 3
Curcumin and its derivatives can block an enzyme important for making testosterone, with one derivative being particularly strong.
research Estrogen-Dependent Development of Sex Differences in Somatostatin Neurons of the Hypothalamic Periventricular Nucleus
Male rats have more somatostatin neurons than females due to testosterone converting to estrogen during early development.
research Clinical Characterization of Men with Long QT Syndrome and Torsades de Pointes Associated with Hypogonadism: A Review and Pharmacovigilance Study
Low testosterone in men is a risk factor for a specific heart rhythm issue, and testosterone treatment may help prevent it.
research No Metabolic Impact of Surgical Normalization of Hyperandrogenism in Postmenopausal Women with Ovarian Androgen-Secreting Tumors
Surgery to lower high testosterone in postmenopausal women with certain ovarian tumors doesn't significantly affect their metabolism.
research Immuno-Endocrinology of COVID-19: The Key Role of Sex Hormones
Sex hormones may affect COVID-19 severity, with estrogen possibly reducing risk and testosterone potentially increasing it.
research Observation of Phenotypic Variation Among Indian Women With Polycystic Ovary Syndrome (PCOS) From Delhi and Srinagar
Indian women with PCOS from Delhi and Srinagar show different symptoms, with Delhi women having higher obesity and blood sugar issues, and Srinagar women showing more hair growth and testosterone levels.
research Safety Aspects of Androgen Treatment with 5α-Dihydrotestosterone
DHT is a strong androgen that may pose less risk to the prostate compared to testosterone.
research Androgen Binding to Cytosol and Nuclei of Hamster Sebaceous Glands
Dihydrotestosterone specifically binds to hamster sebaceous glands, with a higher affinity than testosterone.
research Cross-Sex Hormone Therapy in Australia: The Prescription Patterns of Clinicians Experienced in Adult Transgender Healthcare
Australian doctors experienced in adult transgender healthcare mostly prescribe intramuscular testosterone and oral estradiol, recommend mental health assessments before hormone therapy, and support improved training and guidelines.
research Antiandrogenic Activities of Glycyrrhiza Glabra in Male Rats
Liquorice may reduce testosterone and affect male reproductive organs, potentially helping treat conditions like prostate cancer.
research The Effect of Alfacalcidiol and Metformin on Phenotype Manifestations in Women with Polycystic Ovary Syndrome – A Preliminary Study
Alfacalcidiol and metformin together lowered testosterone in women with PCOS, but did not significantly improve acne, hair growth, or pregnancy rates.
research Urinary Steroids in Men with Male-Pattern Alopecia
Men with male-pattern baldness have higher levels of certain testosterone metabolites and may have more active androgen metabolism.
research An Ovarian Leydig Cell Tumor Undetected by Ultrasound in a Postmenopausal Woman with Hirsutism and Hyperandrogenism
A postmenopausal woman's hirsutism and high testosterone levels improved after surgery for an ovarian tumor not seen on ultrasound.
research Molecular Basis of Androgen Action on Human Sexual Desire
Testosterone significantly affects sexual desire in both men and women, but its impact on women is more complex and influenced by psychological factors.
research Polymorphisms in Androgen and Estrogen Receptor Genes: Effects on Male Aging
Changes in testosterone and estrogen receptor genes can affect how men age, influencing body fat, hair patterns, and possibly leading to skin disorders.
research Inhibitory Effects of Serenoa Repens on the Kinetics of Pig Prostatic Microsomal 5α-Reductase Activity
Saw palmetto extract can block the enzyme that converts testosterone in pig prostate cells.
research Association Between Severity of Depression and Clinico-Biochemical Markers of Polycystic Ovary Syndrome
Depression severity is not linked to PCOS markers like BMI, insulin resistance, or testosterone levels.